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Join Dr. Davis ’ Infinite Health Boot Camp January 5th to the 14th
Undoctored is now Dr. Davis Infinite Health (www.DrDavisInfiniteHealth that goes live in early January) as its name suggests, puts personal control over health back in your hands. We continue many of the strategies of the Wheat Belly lifestyle but expand them with lessons learned through this worldwide experience, while adding new dimensions and practices. While we make the transition to Dr. Davis Infinite Health and away from Undoctored, the concepts and practices remain the same. The Dr. Davis’ Wild, Naked, and Unwashed program causes you to revert back to the way humans were supposed to be eating and living all ...
Source: Wheat Belly Blog - December 22, 2021 Category: Cardiology Authors: April Duval Tags: Open Undoctored Source Type: blogs

Food Intolerances: A Warning of Bad Things Ahead
I’ve recently discussed how the majority of food intolerances, whether to FODMAPs, histamine, nightshades, fructose, etc., are really manifestations of dysbiosis and SIBO. Here is another way to view these phenomena: Food intolerances are your body’s signal to you that serious deterioration in your health is coming. In other words, if all you do is choose to reduce or eliminate the offending food, you are still left with the massive disruption of your intestinal microbiome that caused the food intolerance in the first place, along with increased intestinal permeability and endotoxemia. So say you eliminate ferm...
Source: Wheat Belly Blog - November 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open microbiota prebiotic probiotic sibo small intestinal bacterial super gut undoctored wheat belly Source Type: blogs

Gastroenterology Embraces Artificial Intelligence
AI and machine learning have the potential to redefine the management of several GI disorders.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.Colonoscopy is one of the true success stories in modern medicine.Studies have demonstrated that colonoscopy screening detects the cancer at a much earlier stage, reducing the risk of invasive tumors and metastatic disease, andreducing mortality. However, while colorectal cancer is highly preventable, it is thethird leading cause of cancer-related deathsin the U.S. A...
Source: Life as a Healthcare CIO - October 13, 2021 Category: Information Technology Source Type: blogs

Fight Aging! Newsletter, September 27th 2021
This study provides causal evidence of a lipoprotein-Aß /capillary axis for onset and progression of a neurodegenerative process. The Staggering Ongoing Cost of Failing to Aggressively Pursue the Development of Rejuvenation Therapies https://www.fightaging.org/archives/2021/09/the-staggering-ongoing-cost-of-failing-to-aggressively-pursue-the-development-of-rejuvenation-therapies/ No feasible amount of funding that could be devoted to the research and development of rejuvenation therapies would be too much. If near all other projects were dropped, and institutions radically retooled on a short term basis...
Source: Fight Aging! - September 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Prevention of colon cancer begins . . . in the mouth?
The post Prevention of colon cancer begins . . . in the mouth? appeared first on Dr. William Davis.
Source: Wheat Belly Blog - September 22, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota undoctored Source Type: blogs

I Am a Decision Maker, Not a Bookkeeper
By HANS DUVEFELT Perhaps it is because I love doctoring so much that I find some of the tools and tasks of my trade so tediously frustrating. I keep wishing the technology I work with wasn’t so painfully inept. On my 2016 iPhone SE I can authorize a purchase, a download or a money transfer by placing my thumb on the home button. In my EMR, when I get a message (also called “TASK” – ugh) from the surgical department that reads “patient is due for 5-year repeat colonoscopy and needs [insurance] referral”, things are a lot more complicated, WHICH THEY SHOULDN’T HAVE TO BE! For this routine task, I can...
Source: The Health Care Blog - September 20, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care EMR Hans Duvefelt Source Type: blogs

Fight Aging! Newsletter, September 13th 2021
In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - September 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mitochondrial-Derived Peptides as Targets for Cardiovascular Disease Therapies
This review takes a look at a number of peptides related to mitochondrial function, and which are thought to potentially provide therapeutic benefit. Some are interesting in the context of aging. As is the case for most peptides with enough scientific literature to justify a review paper, availability and use is somewhat ahead of the science. Peptide manufacture is easy enough and cheap enough that most studied peptides can be purchased from established manufacturers. That certainly doesn't mean that they are in fact useful at the end of the day! This marketplace is very much like the supplement marketplace in that respect...
Source: Fight Aging! - September 10, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 6th 2021
In conclusion, patients over 90 years of age had an overall low prevalence of fractures and relative preservation of bone health, suggesting a preserved bone molecular profile in these individuals. Epigenetic factors and activity levels might also have favorably affected bone health. The low percentage of osteoporosis and fractures likely reduced the morbidity and mortality in this population, potentially contributing to their overall longevity. Building a Therapy for Aging Based on SIRT6 Upregulation https://www.fightaging.org/archives/2021/08/building-a-therapy-for-aging-based-on-sirt6-upregulation/ Ge...
Source: Fight Aging! - September 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

September is Prostate Cancer Awareness Month: Get Educated!
The prostate,  a mall organ located just below the bladder and in front of the rectum, can cause men a lot of anxiety and trouble as they age. It wraps around the urethra (the tube that carries urine and semen out of the body). As men age, the prostate tends to grow larger which can eventually cause any number of health issues including urine retention, but it can become cancerous, as well. Read more on the Egosancares blog about prostate function and why things go wrong: Minding Our Elders: Caregivers Share Their Personal Stories. “I hold onto your book as a life preserver and am reading it slowly on purpose...I d...
Source: Minding Our Elders - September 4, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Fecal Microbiota Transplant as a Treatment for Neurodegenerative Conditions
It is thought that an appreciable fraction of the chronic inflammation of aging is caused by changes in the gut microbiome. There is a bidirectional interaction between the immune system and the microbial populations of the intestinal tract. The immune system gardens these populations, destroying problematic microbes. Microbes secrete metabolites and other molecules that can either benefit or harm the function of the immune system, the harms caused particularly by those microbes capable of provoking a sustained inflammatory response. The immune system declines with age for a range of reasons, and reduced efficacy in immune...
Source: Fight Aging! - September 3, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Top 12 Health Chatbots In 2021
Over the past years, smart algorithm-powered, text- or voice-based interfaces have multiplied, and they are also taking their place in healthcare. The Medical Futurist believes Molly, Ginger, Replika and the others will ease the burden on doctors in primary care and help patients learn to take care of their health responsibly. Would you like to try one? Check out the following video about healthcare chatbots: The age of talking algorithms is here In 2018, Google stunned the world with the latest feature of the Google Assistant, Duplex, which was able to make an appointment in a hair salon in eerily hum...
Source: The Medical Futurist - August 31, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design AI chatbot digital health Innovation List medical Personalized medicine technology chatbots health chatbot Source Type: blogs

What is Primary Health?
I’ve been writing a blog post on this topic for a few months.  It’s gone through several iterations and has survived a half-dozen friendly editors.  This post isn’t that post, which still needs honing and will follow in the coming days.  This post is the personal prelude – the why that perhaps is important to share before the what. Simon Sinek says we should start with why.  Here goes: My decision to go to medical school was long-delayed.  Indeed – I took no science classes in college – assuring myself that I would not follow the path of my father and grandfathers – all of wh...
Source: Docnotes - August 25, 2021 Category: Primary Care Authors: Jacob Tags: Health Uncategorized Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Improved Manipulation of " Eat Me " and " Don ' t Eat Me " Markers in the Context of Cancer
One of the more interesting discoveries of the past few decades in cancer research has been the identity of surface markers such as CD47 that normally act to protect important cells from being attacked and destroyed by immune cells - a "don't eat me" signal. Cancers abuse such mechanisms in a variety of ways, both directly, in cancerous cells, and indirectly, via subversion of regulatory immune cells that are protected by such surface markers, in order to suppress the immune response to the cancer. Targeting CD47 has proven a promising approach to the treatment of cancer, but it has side-effects. There are always necessary...
Source: Fight Aging! - August 19, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs