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CRISPR-Equipped Bacteria Detect Tumors
Researchers at the University of California San Diego have created a bacterial sentinel system that can alert clinicians to the presence of tumors. The technology takes advantage of the specificity of the CRISPR system and the tendency of bacteria to...
Source: Medgadget - September 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Genetics Oncology UCSD Source Type: blogs

These Popular Drinks Double Risk Of Colorectal Cancer
The popular drinks linked to 100% increase in colorectal cancer risk in adults before the age of 50.
Source: PsyBlog | Psychology Blog - August 20, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Cancer Source Type: blogs

Removing workflow burdens and improving access for colorectal cancer screenings
After much outcry, UnitedHealthcare announced that they are no longer moving forward with their controversial prior authorization policy that would require members to get approval from the insurance company to receive a diagnostic colonoscopy to detect cancer. Instead, UnitedHealthcare has discussed implementing an alternative: an advanced notification process that would require physicians to collect and Read more… Removing workflow burdens and improving access for colorectal cancer screenings originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 16, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

The Top 10 Health Chatbots
This study from March 2023 reports how an app developed to help patients’ bowel preparation can increase compliance and thus, the number of successful colonoscopies. In some cases, health chatbots are also able to connect patients with clinicians for diagnosis or treatment, but that is one step further down the line. The general idea is that in the future, these talking or texting smart algorithms might become the first contact point for primary care. Patients will not get in touch with physicians or nurses or any medical professional with every one of their health questions but will turn to chatbots first. If th...
Source: The Medical Futurist - August 1, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design health chatbot Innovation List medical Personalized medicine AI technology digital health chatbots Source Type: blogs

Closing the Gap: Why Healthcare Needs More Gender Diversity in Leadership
The following is a guest article by Dr. Erica Barnell, MD, PhD, Co-Founder and Chief Science Officer at Geneoscopy Women comprise 70% of the healthcare workforce and 59% of medical, biomedical, and health sciences graduates, yet are the minority at leadership levels — holding only 25% of senior executive roles. As a result, the lack of women in significant decision-making positions is evident. According to U.S. Census estimates, no single ethnic or racial group will represent a majority of the U.S. population by 2055. The potential for more positive patient care experiences, greater innovation, and improved organizatio...
Source: EMR and HIPAA - July 26, 2023 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership Clinical Health IT Company Healthcare IT Dr. Erica Barnell Dr. Erica Barnell MD PhD Gender Bias Gender Diversity in Healthcare Leadership Geneoscopy Women in Healthcare Women in Leadership Women in STEM Women's H Source Type: blogs

Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells. Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing What is Known of the Biochemistry of Klotho Relevant to Effects on Life Span
Increased klotho expression increases longevity in mice, while reduced klotho expression accelerates aging. The most well studied effects of klotho on organ function involve the kidney and brain, where in both cases it appears protective via a number of different mechanisms. Unfortunately, klotho expression declines with age. Whether treating humans with therapies that increase levels of klotho will produce effects that are as large as those observed in mice remains to be seen. Programs that might lead to treatments remain at a preclinical stage of development, though recently advanced to the point of testing in non-human ...
Source: Fight Aging! - July 21, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

MA for Tomorrow: Moving Beyond the Status Quo to Advance Concrete Policy Changes for the Future of Medicare Advantage
BY CECI CONNOLLY AND MICHAEL BAGEL Medicare Advantage (MA) has passed the tipping point, delivering coverage and care to more than half of the senior population in the US. The Congressional Budget Office projects more than 60 percent of people 65 years and older will be in the program by 2030. As enrollment soars and interest in value-based health care grows, it is imperative policymakers modernize the program that is expected to cost $7.5 trillion over the next decade. Rather than taking the standard Washington posture of declaring victory or defending the status quo, our provider-aligned, nonprofit member pla...
Source: The Health Care Blog - June 12, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Ceci Connolly MA for Tomorrow Medicare Advantage Michael Bagel Source Type: blogs

Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How modern lifestyle changes are disrupting our immune systems
In addition to a steep increase in prevalence, in recent decades, we have seen an evolution in the ways our immune system misbehaves: eosinophilic esophagitis, mast cell disorders, and early onset colon cancer, among many others. This data alone should remind us that we are an ever-evolving species. With our rapidly changing lifestyle over the Read more… How modern lifestyle changes are disrupting our immune systems originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - June 9, 2023 Category: General Medicine Authors: Tags: Conditions Allergies & Immunology Source Type: blogs

Surveying Laboratory Tests From a Health IT Perspective
We read that “70% of today’s medical decisions depend on laboratory test results,” according to the CDC. This three-part series looks at modern tests from a health IT perspective. How can we make them more accurate and delivery faster results? Which ones can we move into the home? How do we eliminate wasteful, unnecessary tests? This first article offer an overview of tests and their context. Overview of Testing Gerry Miller, founder and CEO of Cloudticity, classifies the value of a test by several factors: How easy is the test to acquire? How complex is the test to administer? How much does it cost? Most im...
Source: EMR and HIPAA - June 7, 2023 Category: Information Technology Authors: Andy Oram Tags: Health IT Company Healthcare IT Interoperability CDC CLIA Cloudicity Direct to Consumer Lab Testing Dr. Yair Lewis Epstein Becker Green Gerry Miller Healthcare Interoperability IVD Laboratories Labs Navina Robert Hearn Sand Source Type: blogs

The Gut Microbiome Differs in Characteristic Ways in Patients with Precancerous Colon Polyps
The gut microbiome changes with age, the relative abundance of microbial populations shifting in ways that appear connected to chronic inflammation and dysfunction of the intestinal epithelium and intestinal barrier function. Cancer of the colon is an important cause of human mortality, and there is some hope that finding ways to prevent or reverse gut microbiome aging, such as via fecal microbiota transplant from young individuals, will go some way to minimizing colon cancer incidence. Colorectal cancer is the second leading cause of cancer-related death in the U.S., and rates of colorectal cancer are rising amon...
Source: Fight Aging! - June 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Intratumoral Bacteria as an Injectable Anti-Cancer Treatment
Scientists at the Japan Advanced Institute of Science and Technology in Ishikawa, Japan have developed an anti-cancer treatment that consists of bacteria that are naturally found inside some tumors. Isolating and then injecting these bacteria into ex...
Source: Medgadget - May 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology JAIST Source Type: blogs

Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species. We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs