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Age-Related Diseases are Just the Names we Give to Portions of Aging
Aging is a process of damage accumulation in cells and tissue structures, followed by reactions to that damage, some of which are compensatory and some of which make matters worse, and lastly the consequent failure of biological systems necessary to support health and life. Age-related diseases are names we give to some of the aspects of system failure, but they are not distinct from aging. One cannot draw a line between aging and age-related disease; it is a futile endeavor, and that the medical industry and regulatory bodies are set up to do so is one of the major challenges facing those who want to develop commercial re...
Source: Fight Aging! - February 6, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Race, ethnicity and social history
People often talk past each other because they ascribe different meanings to the same word. Sometimes they don ' t realize they are doing this, sometimes they ought to know better. For example, I knew a guy who insisted that the concept of " organic food " was nonsensical because " organic " means carbon compounds, and all food consists of carbon compounds. He could not be made to see that the word was being used in a different sense. (You could also say that all food is organic because it comes from organisms. Same mistake.)Here in the U.S. we use " white people " as a shorthand term, but most people, most of the time, ar...
Source: Stayin' Alive - February 1, 2019 Category: American Health Source Type: blogs

Fight Aging! Newsletter, January 28th 2019
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - January 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 14th 2019
In conclusion, reduction of LDL-C to less than 50 mg/dl seems safe and provides greater CV benefits compared with higher levels. Data for achieved LDL-C lower than 20-25 mg/dl is limited, although findings from the above mentioned studies are encouraging. However, further evaluation is needed for future studies and post-hoc analyses. Wary of the Beautiful Fairy Tale of Near Term Rejuvenation https://www.fightaging.org/archives/2019/01/wary-of-the-beautiful-fairy-tale-of-near-term-rejuvenation/ One might compare this interview with researcher Leonid Peshkin to last year's discussion with Vadim Gladyshev. ...
Source: Fight Aging! - January 13, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The OMICS Universe And Its Future
The OMICS acronym crawled into the hive mind of the life science community as the Marvel universe onto the movie screens: slowly but successfully. Genomics, transcriptomics, proteomics, metabolomics, methylomics or surfaceomics occupy a growing field of research in systems biology lately. It will be an even more significant strand in the future with practical ramifications, such as transcriptomic tests for disease risks. Thus, it is recommended to get familiar with the OMICS universe. Here’s a glimpse of it. Systems biology and the messenger game When I was in fourth grade, a fun game sometimes referred to as the ‘...
Source: The Medical Futurist - January 5, 2019 Category: Information Technology Authors: nora Tags: Biotechnology Future of Medicine big data biology cancer clinical research genetics genomics metabolome metabolomics precision medicine proteome proteomics systems biology transcriptome transcriptomics treatment Source Type: blogs

Philips HealthWorks Supports Startups Using AI for Radiology, Ultrasound, and Oncology: Interview
In Philips innovation hubs located in Cambridge, Massachusetts, Eindhover, Netherlands, Bangalore, India, and Shanghai, China, 19 startups out of 750 applicants are taking part in an intensive, 12-week Philips HealthWorks program to accelerate their ...
Source: Medgadget - December 19, 2018 Category: Medical Devices Authors: Michael Batista Tags: Exclusive Informatics Medicine Net News Oncology Radiology Society Source Type: blogs

Heart failure and salt: The great debate
“Let there be work, bread, water, and salt for all.” — Nelson Mandela Salt: without it, food can seem tasteless. It is the reason sea water burns our eyes and skin. Some people enjoy salt water baths. Is it good for us? Is it not? Do we really know? In modern medicine, we tend to have a generally negative feeling about sodium, the element found in salt. Excessive sodium intake is linked to water retention, and it is also a risk factor for high blood pressure. Both excessive sodium intake and high blood pressure are major risk factors for developing heart failure, and for causing complications in those with existing h...
Source: Harvard Health Blog - December 18, 2018 Category: Consumer Health News Authors: James Januzzi, MD Tags: Diet and Weight Loss Health Healthy Eating Heart Health Source Type: blogs

Designer Babies: A Dystopian Sidetrack of Gene Editing
A Chinese scientist shocked the scientific community a couple of days ago with the announcement of having modified the very blueprint of life. If his claims are true, he tried to bestow two baby girls the ability to resist possible future infections with HIV. The outrage shows that humanity is not prepared to utilize the power of gene editing on embryos yet. We have no idea about the biological consequences, and we haven’t tackled the necessary legal and ethical issues. Genes to become toys of the “Gods”? Humanity has come a long way since Aldous Huxley pinned down how methods of genetic engineering, biological cond...
Source: The Medical Futurist - December 15, 2018 Category: Information Technology Authors: nora Tags: Bioethics Future of Medicine Genomics designer babies designer baby Gene gene editing genes Genome genome sequencing Health Healthcare healthcare system Innovation technology Source Type: blogs

The Power of Mobile Health
2018 was a very busy year, requiring extensive international travel —I racked up more than 400,000 miles this fall.  But now that my schedule is a bit more manageable, I plan to start posting again to “Life as a Healthcare CIO”. In addition to my travels to China, Japan, Australia and a long list of other countries, I managed to find the time to work with my esteemed co-author Paul Cerrato on our third book, The Transformative Power of Mobile Medicine. We wanted to share the Preface with readers and have included it below, along with a link to Elsevier ’s web site for those interested in reading the entire boo...
Source: Life as a Healthcare CIO - December 14, 2018 Category: Information Technology Source Type: blogs

The Macro View – Health, Financial And Political News Relevant To E-Health And The Health Sector In General.
December 13, 2018 Edition.Trump is at is again firing his Chief of Staff, which by my count, leaves only one adult in the room (Jim Mattis). This week we will see how the extradition from Canada of a ‘Chinese Princess’ will go – China is, of course, furious and so have grabbed a Canadian citizen. At least she is now out on bail. In parallel the trade issues with China seem to be a bit better in the last few days.Brexit looked like it would come to a head this week, but May survived and the mess seems worse - . Angela Merkel also has a successor.In OZ we have the pollies on holidays until Feb 12, 2019 after a chaotic ...
Source: Australian Health Information Technology - December 13, 2018 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Spray Gel Helps Prevent Cancer Spread Following Surgery
All too often after tumor resections cancers end up spreading to other parts of the body. Metastasis is not well understood, but researchers at University of California, Los Angeles, University of North Carolina, Chapel Hill, South China University...
Source: Medgadget - December 11, 2018 Category: Medical Devices Authors: Editors Tags: Nanomedicine Source Type: blogs