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Interview with Ori Geva, CEO of Medial EarlySign: A Healthcare Data Analytics Startup
Predictive analytics is the practice of learning from historical data in contemplation of making decisions about the future. Predictive analytics is not new to healthcare. However, in the past it has been limited by many factors, including data avail...
Source: Medgadget - March 22, 2018 Category: Medical Devices Authors: Kenan Raddawi Tags: Exclusive Informatics Medicine Public Health Source Type: blogs
Yi Gang to Head China ’s Central Bank
Yi Gang, an American-trained economist who taught at the University of Indiana, will take over as governor of the People ’s Bank of China. Since 2008, he has been deputy governor under Zhou Xiaochuan, who became head of the bank in 2002. The unexpected appointment of Mr. Yi will provide continuity at the PBOC and lend credibility to the pledge for financial liberalization.Following his appointment,Yi Gang declared: “The main task is that we should implement prudent monetary policy, push forward the reform and opening-up of the financial sector, and maintain the stability of the entire financial sector.”In November 20...
Source: Cato-at-liberty - March 19, 2018 Category: American Health Authors: James A. Dorn Source Type: blogs
Scientists Develop Technique to Mass Produce Drug Delivery Nanovesicles
Numerous technologies that use and help nanovesicles to deliver drugs to disease sites have been developed over the past few years, as any regular reader of Medgadget can attest to. We’re now at a stage when figuring out how to manufacture so-c...
Source: Medgadget - March 15, 2018 Category: Medical Devices Authors: Editors Tags: Materials Nanomedicine Source Type: blogs
Fight Aging! Newsletter, March 12th 2018
This study identifies the missing link between Lewy bodies and the type of damage that's been observed in neurons affected by Parkinson's. Parkinson's is a disorder of the mitochondria, and we discovered how Lewy bodies are releasing a partial break-down product that has a high tropism for the mitochondria and destroys their ability to produce energy."
Lewy bodies were described a century ago, but it was not until 1997 that scientists discovered they were made of clumps of a misfolded protein called α-synuclein. When it's not misfolded, α-synuclein is believed to carry out functions related to the transmission of...
Source: Fight Aging! - March 11, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Senolytic Peptide FOXO4-DRI
The objective is to wind up with the right amount of FOXO4-DRI dissolved in phosphate buffered saline in a sealed vial, ready to be used with the injection system, and with as little contamination as possible from the environment. Depending on the size of the vial, it might contain doses for multiple injections - in fact it is much easier to set things up this way. FOXO4-DRI dissolves very readily in saline, so placing a single human dose into 0.5ml or 1ml is quite feasible. A 3ml vial can hold three doses for the treatment without issue.
One approach is to measure out FOXO4-DRI by weight using a suitable microscale...
Source: Fight Aging! - March 5, 2018 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
Fight Aging! Newsletter, February 26th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - February 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How Would One Go About Building a Company to Bring Cheap Senolytics to the World?
Let us for a moment choose to believe that the dasatinib and quercetin combination is a senolytic treatment that does as well in humans as it does in mice. This is to say it kills about 25-50% of senescent cells in the tissues usually most affected by oral medications, meaning the kidney, liver, and cardiovascular system, and some unknown but lower fraction elsewhere. Whether or not this is the case has yet to be determined; the first pilot studies are still running at Betterhumans, and they likely won't tell us the size of the effect in terms of fraction of cells removed. Viable assays for cellular senescence that can be ...
Source: Fight Aging! - February 21, 2018 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
Andrographolide and bone destruction
This study shows that andrographolide inhibits the development of osteoclasts ( = the cells that chew away at our bones, which is fine in a healthy situation, not fine in cancer where everything goes nutso), while increasing the presence of osteoblasts (bone builders).
The researchers say that the current therapies used to treat osteolytic diseases have many unwanted side effects. And they’re not just referring to bisphosphonates (which can cause osteonecrosis of the jaw) but also to new treatments such as the monoclonal antibody denosumab, Denosumab can cause low calcium levels, weakness, constipation, back/arm/leg pa...
Source: Margaret's Corner - February 21, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll Source Type: blogs
Fermented foods to beat back SIBO and dysbiosis
If you’ve been following the Wheat Belly discussions, you already know that efforts to cultivate healthy bowel flora in the wake of wheat/grain elimination is a key factor in regaining health. While I’ve emphasized the importance of a high-potency (e.g., 50 billion or more CFUs per day), multi-species probiotic supplement and prebiotic fibers, I’ve not focused on the importance of fermented foods. This issue comes to light in particular with our experience in battling small intestinal bacterial overgrowth, or SIBO.
Dysbiosis, or disrupted composition of bowel flora in the colon, is exceptionally common, e...
Source: Wheat Belly Blog - February 19, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle bowel flora fermented foods grain-free Inflammation kefir kimchi kombucha probiotic sibo small intestinal bacterial overgrowth yogurt Source Type: blogs
Sunday Sermonette: Utter Absurdity
Genesis 7 doesn ' t really add much information to what we already got in chapter 6, but it does give us the opportunity for further ridicule.7 TheLord then said to Noah, “Go into the ark, you and your whole family, because I have found you righteous in this generation.2 Take with you seven pairs of every kind of clean animal, a male and its mate, and one pair of every kind of unclean animal, a male and its mate,3 and also seven pairs of every kind of bird, male and female, to keep their various kinds alive throughout the earth.4 Seven days from now I will send rain on the earth for forty days and for...
Source: Stayin' Alive - February 18, 2018 Category: American Health Source Type: blogs
Nanomachines Create Clots Inside Vessels Feeding Cancer Tumors
Researchers from Arizona State University and National Center for Nanoscience and Technology of the Chinese Academy of Sciences have developed a remarkable new way of killing tumors. They’ve developed robot-like nanoscale devices that cling to ...
Source: Medgadget - February 16, 2018 Category: Medical Devices Authors: Editors Tags: Nanomedicine Oncology Source Type: blogs
Fight Aging! Newsletter, January 15th 2018
This study is the longest, prospective randomized controlled trial that has documented the physiological effects of supervised, structured exercise training in a group of sedentary but healthy middle-aged adults. The key finding is that 2 years of exercise training performed for at least 30 minutes, 4 to 5 days per week, and including at least 1 high-intensity interval session per week results in a significant reduction in LV chamber and myocardial stiffness. The use of high-resolution, invasively measured LV pressure-volume curves and comparison with an attention control group enhances the confidence in this conclusion. T...
Source: Fight Aging! - January 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Chemotherapeutic Senolytic Drug Candidates
The objective here is a set of tests that anyone can run without the need to involve a physician, as that always adds significant time and expense. Since we are really only interested in the identification of large and reliable effects as the result of an intervention, we can plausibly expect a collection of cheaper and easier measures known to correlate with age to be useful. Once that hill has been climbed, then decide whether or not to go further - don't bite off more than is easy to chew for a first outing.
From an earlier exploration of likely tests, I picked the following items on the basis of a likely connect...
Source: Fight Aging! - January 12, 2018 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
Tai Chi For Seniors: Exercises, Benefits, and Tips For The Elderly
View Original Article Here: Tai Chi For Seniors: Exercises, Benefits, and Tips For The Elderly
Tai chi, a form of Chinese martial arts that focuses on slow, controlled movements. It’s low impact and gives people with limited mobility a chance to improve their balance, range of motion and coordination. Research shows that tai chi for seniors can reduce the incidence of falls in elderly and at-risk adults by about 43 percent. With fewer than 34 percent of aging adults getting enough exercise, it’s important for caregivers, older individuals and people who work with seniors to know about this gentle but effective activity...
Source: Shield My Senior - January 8, 2018 Category: Geriatrics Authors: Vin Tags: Senior Safety Source Type: blogs
