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Why are mRNA vaccines so exciting?
The very first vaccines for COVID-19 to complete Phase 3 testing are an entirely new type: mRNA vaccines. Vaccines of this type have never before been approved for use in any disease. How do they differ from traditional vaccines, and what makes them so exciting? How traditional vaccines work The main goal of a vaccine for a particular infectious agent, such as the virus that causes COVID-19, is to teach the immune system what that virus looks like. Once educated, the immune system will vigorously attack the actual virus, if it ever enters the body. Viruses contain a core of genes made of DNA or RNA wrapped in a coat of pro...
Source: Harvard Health Blog - December 10, 2020 Category: Consumer Health News Authors: Anthony Komaroff, MD Tags: Coronavirus and COVID-19 Health Vaccines Source Type: blogs

Fight Aging! Newsletter, November 16th 2020
This study conclusively demonstrates the long-speculated relationship between aging, gene regulation, and somatic damage. The results open up new avenues of research with practical implications. If the same level of coordination reduction between genes is indeed a leading cause for aging phenomena, there may be a need to change course in current efforts to develop aging treatments. Using Oligodendrocyte Extracellular Vesicles to Induce Tolerance to Myelin as a Treatment for Multiple Sclerosis https://www.fightaging.org/archives/2020/11/using-oligodendrocyte-extracellular-vesicles-to-induce-tolerance-to-myelin-a...
Source: Fight Aging! - November 15, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Extreme shock and cardiac arrest in COVID patient
This is a 30-something healthy patient presented with COVID pneumonia who presented to the ED.  He was moderately hypoxic.  He had the following EKG recorded:Low voltage, suggests effusion.(see Ken ' s discussion of low voltage below)There is a QS-wave in V2.There is minimal, probably normal STE in V2-V6.A bedside cardiac ultrasound was normal, with no effusion. He had troponins ordered, and the first returned at 72 ng/L (Abbott Architect hs cTnI; URL for males = 34 ng/L).  An elevated troponin in a COVID patient confers about 4x the risk of mortality than a normal one.He was admitted on oxygen and was&...
Source: Dr. Smith's ECG Blog - November 12, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

9 Technologies That Will Shape The Future Of Dentistry
One of the most common childhood fears is going to the dentist. Who would not relate? Sitting in a huge chair illuminated by blinding light; enduring lengthy seated sessions with someone looking and poking inside your mouth using edgy and frightening devices. And finally, when the torture is over, that same someone tells you not to eat your favourite sweets and instructs you to brush your teeth regularly.  We’ve all been through this as a kid and childhood memories stick with us; just recalling this might send a shiver down your spine. No one likes to go to the dentist in spite of the fact that everyone knows how crucia...
Source: The Medical Futurist - November 3, 2020 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Artificial Intelligence in Medicine Biotechnology E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Medical Education Telemedicine & Smartphones Virtual Reality AI augmented reality dig Source Type: blogs

The hidden long-term cognitive effects of COVID-19
This study also found that a number of patients with COVID suffered strokes. In fact, COVID infection is a risk factor for strokes. A group of Canadian doctors found that individuals over 70 years of age were at particularly high risk for stroke related to COVID infection, but even young individuals are seven times more likely to have a stroke from this coronavirus versus a typical flu virus. Autopsy data from COVID patients in Finland suggests that another major cause of brain damage is lack of oxygen. Particularly worrisome is that several of the patients who were autopsied did not show any signs of brain injury during t...
Source: Harvard Health Blog - October 8, 2020 Category: Consumer Health News Authors: Andrew E. Budson, MD Tags: Brain and cognitive health Coronavirus and COVID-19 Memory Neurological conditions Source Type: blogs

Fight Aging! Newsletter, October 5th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 4, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Trying to Make AI Less Squirrelly
By KIM BELLARD You may have missed it, but the Association for the Advancement of Artificial Intelligence (AAAI) just announced its first annual Squirrel AI award winner: Regina Barzilay, a professor at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL).   In fact, if you’re like me, you may have missed that there was a Squirrel AI award.  But there is, and it’s kind of a big deal, especially for healthcare – as Professor Barzilay’s work illustrates.  The Squirrel AI Award for Artificial Intelligence for the Benefit of Humanity (Squirrel AI is a Chinese-based AI-powere...
Source: The Health Care Blog - September 29, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Kim Bellard Regina Barzilay Squirrel AI award Source Type: blogs

What if Politicians Are the Biggest Medical Supply Chain Risk?
Scott LincicomeThe onset of COVID-19 has amplified public concerns about the supposed fragility of global supply chains, and fueled proposals on the left and the right to boost supply chain “resiliency” through government policies (subsidies, tariffs, “Buy American” mandates, etc.) that are intended encourage the domestic production of essential goods, especially pharmaceuticals and medical devices. Indeed, such “re‐​shoring” plans are one of the few issues on which bot hPresident Trump and Democratic challengerJoe Biden agree. A  lengthy new McKinseyreport on global supply chains, however, shows just how ...
Source: Cato-at-liberty - September 9, 2020 Category: American Health Authors: Scott Lincicome Source Type: blogs

Does the U.S. Semiconductor Industry Really Need Urgent Taxpayer Support to Stop China?
Scott LincicomeToday, the United States Senateapproved the FY2021 National Defense Authorization Act (NDAA), which contains anamendment passed earlier this week, with little floor debate and by a 96-4 margin, that would provide billions of dollars in new federal support for the U.S. semiconductor industry, most notably tax credits and grants for the construction of new domestic manufacturing facilities. The Housepassed a similar bill with asimilar amendment earlier this week, so the legislation now goes to conference, where the subsidies are expected to survive.   The two main reasons for the Senate and House amendments (...
Source: Cato-at-liberty - July 23, 2020 Category: American Health Authors: Scott Lincicome Source Type: blogs

Does air pollution cause Alzheimer ’s disease?
Have you ever spent the day in a city with such bad air pollution that when you blew your nose the mucus had a black tinge? Have you ever coughed as you breathed in diesel fumes from a passing bus and thought to yourself, “Well, that’s a year gone from my life”? Could it actually be true — that air pollution leads to an early death? The answer, in fact, is an unqualified yes. Air pollution causes heart disease, lung disease, and early death It has been known for some time that air pollution causes lung cancer, chronic obstructive pulmonary disease, emphysema, asthma, heart disease, and stroke. One recent study in C...
Source: Harvard Health Blog - July 23, 2020 Category: Consumer Health News Authors: Andrew E. Budson, MD Tags: Alzheimer's Disease Environmental health Healthy Aging Memory Neurological conditions Source Type: blogs

Fight Aging! Newsletter, July 20th 2020
This study was the first to demonstrate a causal relationship between glial senescence and neurodegeneration. In this study, accumulations of senescent astrocytes and microglia were found in tau-associated neurodegenerative disease model mice. Elimination of these senescent cells via a genetic approach can reduce tau deposition and prevent the degeneration of cortical and hippocampal neurons. Most recently, it was shown that clearance of senescent oligodendrocyte progenitor cells in AD model mice with senolytic agents could lessen the Aβ plaque load, reduce neuroinflammation, and ameliorate cognitive deficits. This...
Source: Fight Aging! - July 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Functional dyspepsia: Causes, treatments, and new directions
Functional dyspepsia (FD) is a common condition, loosely defined by some physicians as a stomach ache without a clear cause. More specifically, it is characterized by the feeling of fullness during or after a meal, or a burning sensation in the mid-upper abdomen, just below the rib cage (not necessarily associated with meals). The symptoms can be severe enough to interfere with finishing meals or participating in regular daily activities. Those with FD often go through multiple tests like upper endoscopy, CT scan, and gastric emptying study. But despite often-severe symptoms, no clear cause (such as cancer, ulcer disease, ...
Source: Harvard Health Blog - July 6, 2020 Category: Consumer Health News Authors: Vikram Rangan, MD Tags: Digestive Disorders Mind body medicine Pain Management Source Type: blogs

Podcast: Using Nature and Animals to Manage Anxiety
 When was the last time you simply enjoyed being in nature? Whether it’s a camping trip to the mountains, a walk in the park or just watching the squirrels from your backyard, being in nature is profoundly healing. In today’s Psych Central Podcast, our guest Richard Louv, a journalist, author and co-founder of the nonprofit Children & Nature Network, discusses the science behind nature’s healing powers. What counts as “nature?” Are pets included? What are some modern barriers to accessing nature, and how can we overcome them? Join us for the answers to these questions and more. SUBSCRIBE & REVIEW Gu...
Source: World of Psychology - May 21, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Anxiety and Panic General Green and Environment Interview LifeHelper Mental Health and Wellness Podcast Stress The Psych Central Show Source Type: blogs

Covid-19 Reuters Q & A with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time. These are essentially my notes from Haseltines’s talk. Might we ever achieve herd immunity? There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs

Covid-19 Reuters Newsmaker Broadcast with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time. These are essentially my notes from Haseltines’s talk. Might we ever achieve herd immunity? There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs