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THCB 20th Birthday Classic: As I’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT
Our 20th birthday continues with a few classics coming out. Back in 2005 I was really cutting a lyrical rug, and would never miss a chance to get that Cambridge training in Marxism into use. This essay about whether health care should be a public or private good has always been one of my favorites, even if I’m not sure Starbucks is still making Frappuccinos. And 18 years later the basic point of this essay remains true, even if many of you will not have a clue who Vioxx or Haliburton were or why they mattered back then!
Those of you who think I’m an unreconstructed commie will correctly suspec...
Source: The Health Care Blog - August 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Communism Frappuccinos Source Type: blogs
Fight Aging! Newsletter, July 24th 2023
In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells.
Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Ligature placement caused progressive periodontal disease and bone resorption that was already significant on day 1 post-ligation and continued to increase until day 30. The severity of periodontal disease increased the frequency of activated microglia in the brains on day 30 by 36...
Source: Fight Aging! - July 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Altis Labs Raises US $6 Million in Seed Funding Co-Led by Debiopharm and Benchstrength to Advance AI Platform for Clinical Trials
Debiopharm Innovation Fund and Benchstrength Co-Lead Seed Funding Round Supporting Altis’ AI-Powered Imaging Biomarker Platform
Altis Labs, Inc. (Altis), the computational imaging company accelerating clinical trials with artificial intelligence, today announces the closing of its US $6 million seed financing. Benchstrength and Debiopharm Innovation Fund co-led the round with participation from strategic angels including Doug Foster, the former CEO at digital health company Verana Health, and Richard Gliklich, MD, the Founder and CEO at real-world data company OM1.
“We are thrilled to partner with Benchstrength and Deb...
Source: EMR and HIPAA - July 14, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Altis Labs Bayer Pharmaceuticals Benchstrength Carolina Haefliger MD Debiopharm Debiopharm Innovation Fund Doug Foster Felix Baldauf-Lenschen Health IT Funding Health IT Fundings Health IT Investment Source Type: blogs
Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation.
Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field
https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/
Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred year...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
High-Throughput Testing of Hundreds of Anti-Cancer Drug Combinations
Researchers at ETH Zurich in Switzerland have developed a high-throughput screening method for anti-cancer drugs that they have called “pharmascopy”. To date, the researchers have tested the system with multiple myeloma samples, a cancer ...
Source: Medgadget - May 11, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology ETH Zurich ethz Nature Cancer Source Type: blogs
Emergency Spending Is on the Rise: Here ’s How Congress Can Stop It
Romina Boccia and Dominik LettCongress has spent a combined $1 trillion through supplemental appropriations over the last five years in inflation‐adjusted 2021 dollars. While most of the supplemental spending since 2020 was in response to COVID-19, supplemental appropriations are on the rise over the long term (chart below).Supplemental appropriations are primarily emergency spending that falls outside of regular budgeting procedures. Congress is increasingly using crises as justifications to spend more. Now, the Biden administration has asked Congress to tack on an additional$85 billion in emergency spending to dis...
Source: Cato-at-liberty - December 20, 2022 Category: American Health Authors: Romina Boccia, Dominik Lett Source Type: blogs
Top 8 Most Controversial Stories About Medical Innovations
I spend my days monitoring progress, analysing new trends, and learning about spectacular new initiatives. Needless to say: not just me, but the whole team of The Medical Futurist is fascinated by what we learn. And then sometimes there is a story that just melts the fuses at one or more team members – and our readers.
Below I picked 8 of our favourite controversial stories from – almost exclusively – this year. It’s important to note that controversial doesn’t equal bad/useless. Sometimes it’s just not widely accepted (yet) and so exotic that they can surely provide a unique talking point at a...
Source: The Medical Futurist - December 13, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF 3d printing AI artificial intelligence bioprinting digital health CRISPR designer baby designer babies robotics in healthcare assisted dying DIY blood draw DIY blood test medical innovation deepfake Source Type: blogs
Our Plants Should Be Plants
BY KIM BELLARD
It seems like most of my healthcare Twitter buddies are enjoying themselves at HLTH2022, so I don’t suppose it much matters what I write about, because they’ll all be too busy to read it anyway. That’s too bad, because I was sparked by an article on one of my favorite topics: synthetic biology.
Elliot Hershberg, a Ph.D. geneticist who describes his mission as “to accelerate the Century of Biology,” has a great article on his Substack: Atoms are local. The key insight for me was his point that, while we’ve been recognizing the power of biology, we’ve been going about it ...
Source: The Health Care Blog - November 15, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Public Health HLTH2022 Industrialization Kim Bellard synthetic biology Source Type: blogs
Magnetic Bacteria Target Tumors
Scientists at ETH Zurich in Switzerland have unveiled a technique that weaponizes bacterial cells against tumors. The approach involves using bacteria called Magnetospirillum that are naturally magnetic by virtue of the iron oxide particles they cont...
Source: Medgadget - November 3, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine Oncology ETH Zurich ethz Source Type: blogs
Fight Aging! Newsletter, October 24th 2022
This study shows the uncoupling of lifespan and healthspan parameters (aerobic fitness and spontaneous activity) and provides new insights into SIRT3 function in CR adaptation, fuel utilization, and aging.
HDL Level, Age, and Smoking are the Largest Determinants of Mortality Risk in Old People
https://www.fightaging.org/archives/2022/10/hdl-level-age-and-smoking-are-the-largest-determinants-of-mortality-risk-in-old-people/
An interesting epidemiological study here stratifies the contributions of various metrics to mortality in later life, age 70 and older. The authors find that the largest effects arise ...
Source: Fight Aging! - October 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
There is Such a Thing as Too Much of a Focus on Low-Hanging Fruit in the Longevity Industry
The longevity industry includes a few companies that will genuinely revolutionize the medical industry, such as Maia Biotechnology, the first deployment of a near-universal cancer therapy based on targeting telomerase activity. For every such gem there are, unfortunately, a half dozen companies that are marketing dietary supplements and the like that will do just about nothing to change the human condition. It is a great deal easier to market a supplement than it is to revolutionize the medical industry by developing a completely new biotechnology, and this truth has a significant impact on the funding available to a compa...
Source: Fight Aging! - October 21, 2022 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Fight Aging! Newsletter, September 12th 2022
Discussion of Present Drug Development to Target Senescent Cells
Targeting Senescent Cells to Better Address Cancer and Consequences of Cancer Therapy
Calorie Restriction Suppresses Generation of Immune Cells via Changes to the Gut Microbiome
Arguing for an Expansion of the Hallmarks of Aging
https://www.fightaging.org/archives/2022/09/arguing-for-an-expansion-of-the-hallmarks-of-aging/
The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. This i...
Source: Fight Aging! - September 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 25, 2022 Edition-----The big story this week has been the multiple PM story in Australia with ScoMo. What an amazing saga!In the UK there seems to be an impending collapse of the economy coming unless some-one takes some really smart steps real soon now.Relatively the US has seemed pretty calm this week – just waiting for an impending recession – along with China and Europe.Fair to say things globally are pretty messy!-----Major Issues.-----https://www.afr.com/markets/equity-markets/every-investing-trend-misfires-as-stock-bears-are-crushed-20220814-p5b9o2Every investing trend misfires as stock bears are crushedD...
Source: Australian Health Information Technology - August 25, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines.
Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Career Conversations: Q & A with Medicinal Inorganic Chemist Eszter Boros
Dr. Eszter Boros. Credit: Courtesy of Dr. Eszter Boros.
“As a researcher, you get to learn something new every day, and that knowledge feeds more questions. It’s this eternal learning process, and I find that really enticing about being in science,” says Eszter Boros, Ph.D., an assistant professor of chemistry at Stony Brook University in Stony Brook, New York. Our interview with Dr. Boros highlights her journey of becoming a scientist and her research on biomedical applications of metals.
Q: What drew you to science?
A: I was born and raised in Switzerland, and I went to a linguistics-focused high school the...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 22, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Profiles Source Type: blogs
