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Libella Gene Therapeutics to Run a Patient Paid Trial of Telomerase Gene Therapy
After Bioviva Science, Libella Gene Therapeutics is the second company to take a run at commercializing telomerase gene therapy treatments for human use. Telomerase is the enzyme responsible for lengthening telomeres, repeated DNA sequences at the ends of chromosomes, though it may have other roles. Telomeres are a part of the mechanism that limits the number of times that a somatic cell can replicate. Telomeres shorten with each cell division, and when too short they trigger programmed cell death or cellular senescence followed by destruction by the immune system. Ordinary somatic cells in humans do not express telomerase...
Source: Fight Aging! - November 22, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Improving Medical AI Safety by Addressing Hidden Stratification
Jared Dunnmon Luke Oakden-Rayner By LUKE OAKDEN-RAYNER MD, JARED DUNNMON, PhD Medical AI testing is unsafe, and that isn’t likely to change anytime soon. No regulator is seriously considering implementing “pharmaceutical style” clinical trials for AI prior to marketing approval, and evidence strongly suggests that pre-clinical testing of medical AI systems is not enough to ensure that they are safe to use.  As discussed in a previous post, factors ranging from the laboratory effect to automation bias can contribute to substantial disconnects between pre-clinical performance of AI systems and dow...
Source: The Health Care Blog - October 18, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Data Health Tech Health Technology AI Jared Dunnmon Luke Oakden-Rayner machine learning Source Type: blogs

Gene testing to guide antidepressant treatment: Has its time arrived?
Depressive disorders are among the most common conditions that disrupt lives. Fortunately, medications, psychotherapies, and lifestyle changes are usually successful in treating depression and related disorders, even if symptoms are not entirely eliminated. Sometimes people don’t gain sufficient relief from treatment, or must try several medications before finding one that works well. In an age of exciting advances, including brain imaging and genetic testing, many doctors and patients reasonably hope that new technologies will offer answers. And in fact, for antidepressant choice, several companies sell genetic testing ...
Source: Harvard Health Blog - October 9, 2019 Category: Consumer Health News Authors: Bruce M. Cohen, MD, PhD Tags: Anxiety and Depression Health Mental Health Tests and procedures Source Type: blogs

Cells & Oxygen Availability | Nobel Special | Episode 54 Bonus
Host Kevin Patton summarizes the 2019 Nobel Prize in Physiology or Medicine to three scientists "for their discoveries of how cells sense and adapt to oxygen availability." A special bonus episode.00:41 | Introduction to Bonus Episode02:00 | Sponsored by HAPS02:24 | Summary of Discovery04:13 | Oxygen at Center Stage05:24 | HIF Enters the Scene08:08 | Sponsored by AAA08:26 | VHL - An Unexpected Partner11:37 | Oxygen sHIFts the Balance13:20 | Oxygen Shapes Physiology& Pathology15:15 | Sponsored by HAPI Online Graduate Program15:48 | Our Course23:46 | Staying ConnectedIf you cannot see or activate...
Source: The A and P Professor - October 6, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs

From Theranos To Google Glass: The Biggest Flops In Digital Health
The tech start-up scene, investors, and news-reading audiences reward great stories on the edge of human capabilities – sometimes even on the boundary of science and science fiction – with their attention, money, or invested energy. However, sometimes marketing machines are better than actual technologies, and the ‘little bubbles’ around companies burst. Here, we collected the most promising digital health ideas and companies over the years that proved to be the greatest flops in medical innovation so far. ‘Big little bubbles’ that turned into digital health failures Humans love great sto...
Source: The Medical Futurist - October 2, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Health Sensors & Trackers AI artificial intelligence companies development device digital digital health digital health market gadgets google google glass hype Innovation invention medical device promis Source Type: blogs

How to Amplify Learning in the A & P Course | Episode 53
Host Kevin Patton summarizes many strategies from learning science that can amplify learning in our courses. Also, updates in the role of exosomes in the spread of cancer and how activity type affects the shape of our heart.00:48 | Jargon: Show Notes& Episode Pages05:07 | Sponsored by HAPS07:01 | Role of Exosomes in Spread of Cancer13:20 | Sponsored by AAA13:44 | Activity Type Affects Heart Shape18:03 | Sponsored by HAPI Online Graduate Program18:35 | Amplifying Learning in A&P: ANSWER53:30 | Staying ConnectedIf you cannot see or activate the audio playerclick here. Questions& Feedback:1-833...
Source: The A and P Professor - September 29, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs

23andMe Moving into Clinical Trial Recruitment, a Potential Source of New Income
I have been blogging about23andMe for about six years (see:Update on 23andMe; Time for a Review of FDA Definition of Medical Devices). During that time, I have seen the company evolve from the first major consumer genomics enterprise to a clinical laboratory authorized by the FDA to perform testing for ten diseases or conditions. These are the first direct-to-consumer (DTC) tests authorized by the FDA that provide information about an individual ’s genetic predisposition to certain medical diseases or conditions (see:FDA allows marketing of first direct-to-consumer tests that provide genetic risk information for ce...
Source: Lab Soft News - September 27, 2019 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Food and Drug Administration Genomic Testing Healthcare Information Technology Healthcare Innovations Lab Industry Trends Lab Regulation Lab Standards Medical Consumerism Medical Research Pharmaceutical Industry Source Type: blogs

Episode 53 Intro | TAPP Radio Preview
A brief preview of the upcoming full episode 53, featuring upcoming topics that include tips for amplifying learning in the A&P course, updates regarding the role of exosomes in the spread of cancer and how heart shape relates to human activity.There's more... someword dissections and Kevin's recommendation forThe A&P Professor Book Club.If you cannot see or activate the audio playerclick here.Questions& Feedback:1-833-LION-DEN (1-833-546-6336)FollowThe A&P Professor onTwitter,Facebook,Blogger,Nuzzel,Tumblr, orInstagram!Topics1 minuteStrategies to amplify learning in the A&P courseThe role of exosomes i...
Source: The A and P Professor - September 24, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs

Announcing GuideWell ’s Caring for Caregivers Challenge
SPONSORED POST By CATALYST @ HEALTH 2.0 Caregivers who care for aging, ill and disabled adult family members face a broad array of challenges within their daily lives. These challenges include stress, burnout, financial burdens, career sacrifices, sleep deprivation, depression, isolation, and lack of privacy. GuideWell believes it “takes a village” to sustainably support family caregivers, and that single point solutions are typically not broad enough to provide comprehensive relief to family caregivers. GuideWell, in collaboration with Catalyst @ Health 2.0, is excited to announce the Caring for Caregive...
Source: The Health Care Blog - September 23, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Catalyst @ Health 2.0 Health Tech Health Technology Start-Ups Caring for Caregivers GuideWell home based care Source Type: blogs

The Stress of Choosing the “Right” Food
Does trying to choose the "right" food stress you out? In our information-saturated landscape, choosing what to eat has become more and more complicated.  Food stress is the pressure of making the right choice often makes us self-limit choices.  We avoid buying this food because a television doctor said it is terrible for us.  We choose to eat only certain foods because a celebrity lost weight doing that.  Or we stand in the grocery aisle wondering if we’ll be judged by our family, friends, or community because we don’t buy something with the “right” label.Eating well shoul...
Source: Embrace Your Heart Wellness Initiative - September 18, 2019 Category: Cardiology Authors: Eliz Greene Tags: Diet and Nutrition Tips Stress Management Source Type: blogs

Inside Schizophrenia: Working With Schizophrenia
Everyone complains about work. Having to go to work every day, working too much, not getting paid enough- working can be challenging for so many reasons. Today’s episode focuses on working while having schizophrenia.  Host Rachel Star Withers, a diagnosed schizophrenic, and co-host Gabe Howard share antidotes from their own work lives and speak with fellow schizophrenic Michelle Hammer. Michelle, an award-winning graphic designer and entrepreneur, discusses her struggles working full time and transitioning to working for herself. Cheryl Wallace the Vice President of Programs at Rose Hill Center, a psychiatric treatm...
Source: World of Psychology - September 18, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: A Bipolar, A Schizophrenic, and a Podcast Inside Schizophrenia Mental Health and Wellness Self-Help Employment life with schizophrenia Living With Schizophrenia mental illness at work Psychology working working and schizophrenia Source Type: blogs

Do Virtual Simulations Prepare For Medical Realities?
How do you study organs and complex living structures in two dimensions? It’s like trying to piece together life on the planet in the age of the dinosaurs from fossils – almost impossible. So why do medical schools require students to learn the tricks of the trade from densely written books and PowerPoint presentations? Luckily, the advancement of technology brought in another dimension: virtual reality. So, we looked around to what extent VR as a three-dimensional teaching tool can support medical education. Let’s dive into virtual laparoscopy, simulated empathy, and co. Can simulated realities trick your senses...
Source: The Medical Futurist - September 7, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Medical Education Virtual Reality doctor Health Healthcare medical student nurse study surgeon Surgery technology VR Source Type: blogs

Inside Schizophrenia: Families Impacted by Schizophrenia
 Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, a diagnosed...
Source: World of Psychology - August 21, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Children and Teens Family Inside Schizophrenia Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Mental Disorder Mental illness and Source Type: blogs

Families Impacted by Schizophrenia
  Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, a diagno...
Source: World of Psychology - August 21, 2019 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Children and Teens Family General Inside Schizophrenia Mental Health and Wellness Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Source Type: blogs

Podcast: Is Mental Illness a Made up Disorder?
In this episode, our hosts discuss whether or not mental illness is a real disorder or if it’s just something that medical and pharmaceutical companies made up to make a profit.  SUBSCRIBE & REVIEW “Instead of taking my psychiatric medications this morning, should I have just gone to yoga?” – Michelle Hammer Highlights from ‘Mental Illness Made Up’ Episode [2:00] Is mental illness real? [4:00] Yoga doesn’t cure all mental illnesses, just like it wouldn’t cure cancer. [16:00] Dealing with people who think mental illness is not real. [19:30] Eating disorders are such a stigmatized mental...
Source: World of Psychology - August 5, 2019 Category: Psychiatry & Psychology Authors: Gabe Howard Tags: A Bipolar, A Schizophrenic, and a Podcast Brain and Behavior Disorders General Source Type: blogs