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Fight Aging! Newsletter, June 4th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - June 3, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 28th 2018
This study indicates that frailty and other age-related diseases could be prevented and significantly reduced in older adults. Getting our heart risk factors under control could lead to much healthier old ages. Unfortunately, the current obesity epidemic is moving the older population in the wrong direction, however our study underlines how even small reductions in risk are worthwhile." The study analysed data from more than 421,000 people aged 60-69 in both GP medical records and in the UK Biobank research study. Participants were followed up over ten years. The researchers analysed six factors that could impact on...
Source: Fight Aging! - May 27, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Koalas, Chlamydia, Microbiomania, Katie Dahlhausen, John Oliver, Russell Crowe, and me.
This study aimed to use 16S rRNA gene sequences derived from koala feces to characterize the intestinal microbiome of koalas throughout antibiotic treatment and identify specific taxa associated with koala health after treatment. Although differences in the alpha diversity were observed in the intestinal flora between treated and untreated koalas and between koalas treated with different antibiotics, these differences were not statistically significant. The alpha diversity of microbial communities from koalas that lived through antibiotic treatment versus those who did not was significantly greater, however. Beta diversity...
Source: The Tree of Life - May 18, 2018 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs

Fight Aging! Newsletter, May 14th 2018
This study found that professional chess players had shorter lifespans than those players who had careers outside of chess and argued that this might be due to the mental strain of international chess competition. In the present study, we focused on survival of International Chess Grandmasters (GMs) which represent players, of whom most are professional, at the highest level. In 2010, the overall life expectancy of GMs at the age of 30 years was 53.6 years, which is significantly greater than the overall weighted mean life expectancy of 45.9 years for the general population. In all three regions examined, mean life...
Source: Fight Aging! - May 13, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Patient Modesty: Volume 87
EO, a visitor writing in the Comment section of Volume 86 of this thread title has set the stage for further discussion-- particularly the way male patients are treated within the medical system. I thought his narrative would be appropriate to start this Volume. ..Maurice.Graphic: My composition using ArtRage and appearing as the graphic on the thread "Order vs Chaos in Medical Practice"At Sunday, May 06, 2018 3:55:00 PM,  Though I am encouraged that many of the contributors to this blog have become activists as regards affording male clients (patients) the same rights as female clients when it comes to mode...
Source: blog.bioethics.net - May 7, 2018 Category: Medical Ethics Authors: Maurice Bernstein, M.D. Tags: Health Care syndicated Source Type: blogs

Fight Aging! Newsletter, April 30th 2018
In conclusion, in the Framingham Heart Study population, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated. Recent Research on the Benefits of Exercise in Later Life https://www.fightaging.org/archives/2018/04/recent-research-on-the-benefits-of-exercise-in-later-life/ A sizable body of work points to the ability of older individuals to continue to obtain benefits through regular physical activity, and particularly in the case ...
Source: Fight Aging! - April 29, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Does Immune System Decline Determine the Contribution of Senescent Cells to Aging?
The self-experimentation rumor mill has it that presently available senolytic pharmaceuticals, repurposed chemotherapeutics that can selectively destroy some fraction of senescent cells, can show results for inflammatory conditions in elderly individuals. Equally, they don't appear to produce evident benefits in basically healthy 40-somethings. While senescent cells are indeed a source of chronic inflammation, one should never act on whispers: wait until data from the present or near future clinical studies is published and ratified. We can certainly debate and hypothesize, however, where anecdotes overlap with existing an...
Source: Fight Aging! - April 27, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Does Medical Virtual Reality Make Healthcare More Pleasant?
Medical virtual reality goes entirely against conventional beliefs about technology making healthcare less human, less empathetic and less caring. Virtual reality teaches empathy to med students, makes vaccination for children more sufferable, helps get rid of fears by treating phobias, relieves chronic pain or fulfills the last wishes of the dying. The many faces of medical virtual reality Although the use of virtual reality in healthcare is not widespread yet, the technology holds great promise. Goldman Sachs estimated in its 2016 report that 8 million physicians and medical technicians could make use of augmented reali...
Source: The Medical Futurist - April 24, 2018 Category: Information Technology Authors: nora Tags: Future of Medicine Virtual Reality in Medicine chronic pain empathy Healthcare pain management pediatrics psychology trauma vaccination VR Source Type: blogs

Fight Aging! Newsletter, April 16th 2018
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - April 15, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, April 2nd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - April 1, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What Causes the Chronic Inflammation of Aging?
Many mechanisms of aging are two-way streets: A accelerates B, but B also makes A worse. Or A leads to B that causes C which aggravates A. Chronic inflammation, a persistent and damaging activation of the immune system, is a player in many of these sorts of circular relationships and feedback loops. The open access paper noted here briefly covers some of the known contributions to increased inflammation in aging. Inflammation is a vital part of the way in which the immune system coordinates with tissues in order to repel invaders and respond to injury; it is beneficial when temporary. When inflammation is constant, however...
Source: Fight Aging! - March 26, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, March 19th 2018
In this study, we did not observe significant age-dependent upregulation of the prominent SASP cytokine Il6 in any tissue, although an upward trend was observed that was consistent in magnitude with previous observations in the heart and kidney. This modest age-related upward trend could be explained by a previous report which demonstrated that senescent cell-secreted IL-6 acts in an autocrine manner, reinforcing the senescent state, rather than inducing senescence or promoting dysfunction in neighboring cells. The decreased expression of Il6 with age we observed in the hypothalamus could be indicative of a lack or ...
Source: Fight Aging! - March 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Undoing Aging: An Interview with Aubrey de Grey
The Undoing Aging conference in Berlin is presently underway, a gathering of everyone who is anyone in the rejuvenation research community. It is hosted jointly by the SENS Research Foundation and the Forever Healthy Foundation, and is a unification of the varied themes of the past fifteen years of SENS conferences: the science of aging and its treatment from the earlier SENS conference series mixed with the industry, startup, and commercial development focus of the Rejuvenation Biotechnology series of recent years. The first rejuvenation therapies to be implemented and shown to work, those based on clearance of sen...
Source: Fight Aging! - March 16, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Notes from WIRED Health 2018 at Francis Crick Institute
Set in its new home of the Francis Crick Institute, WIRED Health 2018 brought together world leaders and change-makers in cancer, aging, artificial intelligence, government, medical devices, and pharmaceuticals, to name but a few. Alongside the main...
Source: Medgadget - March 16, 2018 Category: Medical Devices Authors: Tom Peach Tags: Exclusive Source Type: blogs