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Total 241 results found since Jan 2013.

A Nanoparticle Cancer Vaccine Effective Against Multiple Varieties of Cancer
The most important projects in cancer research are those that might produce therapies effective against many different types of cancer. There are too many varieties of cancer and individual tumors can evolve too rapidly for the research community to achieve its goals by working on highly specific therapies. To defeat cancer within the next few decades, the aim must be to produce broadly effective therapies, targeting common mechanisms and vulnerabilities shared by many or all cancers. There projects cost the same as more narrowly applicable approaches, but are much more cost-effective for the results they might produce. Th...
Source: Fight Aging! - April 26, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 3rd 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - April 2, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

When Considering Aging, Don ' t Forget the Microbes
The environment surrounding our tissues and various complex systems such as organs incorporates a great deal of microbial life. We are surrounded by microbes, we have a whole cooperative ecosystem on our skins and another in our guts, and are constantly under attack by less friendly species. From the point of view of a great many classes of microbial life, we mammals are just another resource to be exploited as a basis for unfettered replication. Before the advent of modern medicine, life expectancy was largely determined by infectious disease and other environmental pathogens rather than the fundamental processes of aging...
Source: Fight Aging! - December 22, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Some Adaptive Immune Cells Become More Innate-Like in the Aged Immune System
I stumbled upon an interesting open access paper a few days ago, linked below, in which the authors present their view of immunosenescence, the age-related failure of the immune system, as being in part a process wherein some cells of the adaptive immune system change their characteristics and function to become more like innate immune system cells. It makes for interesting reading, though it is worth bearing in mind that the immune system as a whole is fantastically complex, and in many ways still a dark and unmapped forest. It is easy to theorize unopposed when there is such a lot of empty space remaining on the map, mak...
Source: Fight Aging! - November 24, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Age-Related Decline in Thymic Activity Correlates with Life Span in Dog Breeds
Researchers here report on thymic activity in dog breeds of varying longevity. The thymus plays an important role in the creation of new T cells, but its activity declines with age, most notably in early adulthood via the process of thymic involution, but then further in later life. A lower supply of new immune cells contributes to the age-related decline of the immune system, which is in part a structural problem of too many memory T cells dedicated to specific pathogens and too few naive T cells capable of dealing with new threats. Those threats are not just invading microorganisms, but also harmful senescent and cancero...
Source: Fight Aging! - November 14, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 19th 2016
In conclusion, we found that IS status was associated with a significant increase in Hannum DNA methylation, likely as a consequence of the accumulation of cardiovascular risk factors, and near signification with Horvath method. Patients with IS were biologically older than controls, a difference that was more obvious in young stroke. This could open up the possibility of useful new biomarker of stroke risk. Latest Headlines from Fight Aging! A Profile of Kelsey Moody and Ichor Therapeutics https://www.fightaging.org/archives/2016/09/a-profile-of-kelsey-moody
Source: Fight Aging! - September 18, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Visual Introduction to SENS Rejuvenation Research
The SENS Research Foundation has assembled a set of narrated cellular biochemistry animations that serve as an introduction to the various distinct projects that make up the field of rejuvenation biotechnology. The videos outline the forms of cell and tissue damage that are the root cause of aging and age-related disease, as well as the classes of therapy that could, once constructed, either repair that damage or bypass it entirely. Since aging is exactly an accumulation of damage and the consequences of that damage, repair of the damage is the basis for rejuvenation, the reversal and prevention of degenerative aging and a...
Source: Fight Aging! - September 15, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

New Study Warns of the Dangers of Multiple Vaccinations
Conclusion Neil Z. Miller has outlined some extremely alarming facts and the situation could be far worse, with many adverse reactions left unreported. However, despite his efforts, no mainstream media outlet has reported on this factual and evidence-based paper. Facts are facts, and we, at VacTruth, believe that the time has come to put a stop to this madness. We urge parents to send a copy of Miller’s paper to all relevant health and government departments before it is too late. References https://vactruth.com/2015/04/23/baby-dies-after-13-vaccines/ http://www.jpands.org/vol21no2/miller.pdf http://www.harpocratesspeak...
Source: vactruth.com - September 8, 2016 Category: Allergy & Immunology Authors: Christina England, BA Hons Tags: Christina England Logical Top Stories Multiple Vaccines truth about vaccines Vaccine Death vaccine injury Source Type: blogs

Fight Aging! Newsletter, September 5th 2016
This study is a good example of the degree to which the choice to remain active in later life makes a difference. That implies a range of other choices over the decades in order to raise the odds that you can in fact choose to remain active when older, such as avoiding weight gain. Moderate physical activity is associated with a greater than 50% reduction in cardiovascular death in over-65s. The 12 year study in nearly 2500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30%. High levels of physical activity led to greater risk reducti...
Source: Fight Aging! - September 4, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

8 Ways to Safely Take Charge of Your Health While Avoiding Toxic Vaccines
CONCLUSION Conventional medicine has plans to develop more vaccines targeting every disease imaginable. Diseases targeted include diabetes, autoimmune disorders and cancer. Vaccinations have been causally linked to these diseases. No evidence supports that vaccines are safe or effective at preventing any disease. Instead of using more toxic vaccinations to theoretically prevent a disease, we should avoid all vaccines like the plague. We can then focus on leading a healthy lifestyle, by eating a clean, nutrient dense diet, exercising, sleeping and getting lots of sun.   About the Author: Michelle Goldstein is a mental ...
Source: vactruth.com - September 1, 2016 Category: Allergy & Immunology Authors: Michelle Goldstein Tags: Logical Michelle Goldstein Top Stories Healthy Living Pro Biotics Weston Price Source Type: blogs

Fight Aging! Newsletter, August 29th 2016
This study demonstrates that TNTs play a significant part in the intercellular transfer of α-synuclein fibrils and reveals the specific role of lysosomes in this process. This represents a major breakthrough in understanding the mechanisms underlying the progression of synucleinopathies. These compelling findings, together with previous reports from the same team, point to the general role of TNTs in the propagation of prion-like proteins in neurodegenerative diseases and identify TNTs as a new therapeutic target to combat the progression of these incurable diseases. Shorter Period of Rapamycin Treatment in Mice...
Source: Fight Aging! - August 28, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 1st 2016
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - July 31, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Review of Telomerase as a Therapeutic Target
Telomerase provides the primary mechanism by which cells lengthen their telomeres. In our species only stem cells and cancer cells do this, while in mice more types of cell use more telomerase. Telomere length determines the limit to cell divisions, a little of the length being lost each time a cell divides. Cells that can lengthen their telomeres can continue dividing indefinitely, and that is how stem cells can continually deliver a useful supply of daughter cells to support surrounding tissues. It is also how cancer grows. Cancer and regeneration are the two sides of the same coin of growth and regeneration, one control...
Source: Fight Aging! - July 30, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, July 25th 2016
This study builds on preliminary findings from the first phase of the INTERSTROKE study, which identified ten modifiable risk factors for stroke in 6,000 participants from 22 countries. The full-scale INTERSTROKE study included an additional 20,000 individuals from 32 countries in Europe, Asia, America, Africa and Australia, and sought to identify the main causes of stroke in diverse populations, young and old, men and women, and within subtypes of stroke. To estimate the proportion of strokes caused by specific risk factors, the investigators calculated the population attributable risk for each factor (PAR; an esti...
Source: Fight Aging! - July 24, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Introducing Viral Cancer Therapies into the Spleen Greatly Improves Outcomes
There are plenty of results from the past decade to illustrate that the methodology by which a therapy is delivered makes a great deal of difference to the outcome in patients. Here, for example, researchers have found a way to improve the performance of viruses engineered to preferentially target cancer cells. We've been hearing less of this approach to cancer in the past few years, given the progress and more widespread support for cancer immunotherapy as a technology platform, but there are still many researchers working on the use of viruses in targeted cancer therapy, and a number of promising studies have resulted. ...
Source: Fight Aging! - July 19, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs