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Total 61 results found since Jan 2013.

A Systematic Review and Meta-Analysis of Systemic Antihypertensive Medications with Intraocular Pressure and Glaucoma
: We synthesized the literature on the association between systemic antihypertensive medications with intraocular pressure (IOP) and glaucoma. Antihypertensive medications included beta blockers (BB), calcium channel blockers (CCB), angiotensin converting enzyme inhibitors (ACEi), angiotensin receptor blockers (ARB), and diuretics.
Source: American Journal of Ophthalmology - March 24, 2023 Category: Opthalmology Authors: Gareth Leung, Alyssa Grant, Andrew N. Garas, Gisele Li, Ellen E. Freeman Source Type: research

Ab-externo intraluminal stent for prolonged hypotony and choroidal detachment after Preserflo implantation
CONCLUSION: The management of hypotony and choroidal detachment after a glaucoma drainage device (GDD) implantation is still unstandardized. The ab externo insertion of a nylon suture grants multiple advantages over the other techniques when performed on a PMS tube.PMID:36348628 | DOI:10.1177/11206721221137166
Source: European Journal of Ophthalmology - November 9, 2022 Category: Opthalmology Authors: Enrico Lupardi Gian Luca Laffi Antonio Ciardella Piero Barboni Luigi Fontana Source Type: research

Janssen Presents Updated Data at EHA for Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab cohort of the Phase 1b TriMM-2 study (NCT04108195). Teclistamab, an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA) is being studied in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 Patients in the study, including a high proportion with prior anti-CD38 exposur...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Diagnostic value of culture results from aqueous tap versus vitreous tap in cases of bacterial endophthalmitis
Conclusions Even though the sensitivity and specificity of aqueous tap are low, our results show that in a few cases it identified important organisms, otherwise missed by vitreous sampling alone. Culture of vitreous sample remains the gold standard for isolation of pathogen in bacterial endophthalmitis, but aqueous samples should also be obtained as an adjunct for the diagnosis.
Source: British Journal of Ophthalmology - May 20, 2022 Category: Opthalmology Authors: AlBloushi, A. F., Ajamil-Rodanes, S., Testi, I., Wagland, C., Grant-McKenzie, N., Pavesio, C. Tags: Original articles - Clinical science Source Type: research

Safety, efficacy, and timing of Nd:YAG laser goniopuncture after nonpenetrating deep sclerectomy for glaucoma: A retrospective cohort study
CONCLUSION: Late laser goniopuncture (3-month cut-off) was associated with better intraocular pressure control and less adverse events than early laser goniopuncture.PMID:34779684 | DOI:10.1177/11206721211056585
Source: European Journal of Ophthalmology - November 15, 2021 Category: Opthalmology Authors: Grant Slagle Tyler Bahr Kyle Welburn Joshua Katuri Ezekiel Quittner-Strom William Sponsel Source Type: research

Diagnostic value of culture results from aqueous tap versus vitreous tap in cases of bacterial endophthalmitis
CONCLUSIONS: Even though the sensitivity and specificity of aqueous tap are low, our results show that in a few cases it identified important organisms, otherwise missed by vitreous sampling alone. Culture of vitreous sample remains the gold standard for isolation of pathogen in bacterial endophthalmitis, but aqueous samples should also be obtained as an adjunct for the diagnosis.PMID:33836991 | DOI:10.1136/bjophthalmol-2021-318916
Source: The British Journal of Ophthalmology - April 10, 2021 Category: Opthalmology Authors: Abdulrahman F AlBloushi Sofia Ajamil-Rodanes Ilaria Testi Catherine Wagland Nadine Grant-McKenzie Carlos Pavesio Source Type: research

Deleterious variants in genes regulating mammalian reproduction in Neanderthals, Denisovans and extant humans
This study provides a comprehensive overview of putatively deleterious variants in extant human populations and extinct individuals occurring in 1734 protein-coding genes controlling reproduction and provides the fundaments for future functional studies of extinct variants in human reproduction.STUDY FUNDING/COMPETING INTEREST(S)This study was supported by the Department of Biological Science and by the Office of Research and Sponsored Programs at the University of Tulsa (Faculty Research Grant and Faculty Research Summer Fellowship) to M.A. and the University of Tulsa, Tulsa Undergraduate Research Challenge (TURC) program...
Source: Human Reproduction - January 8, 2021 Category: Reproduction Medicine Source Type: research

Yousefi to develop artificial intelligence to improve glaucoma research, diagnosis
(University of Tennessee Health Science Center) Siamak Yousefi, Ph.D., an assistant professor in the Department of Ophthalmology and the Department of Genetics, Genomics, and Informatics at the University of Tennessee Health Science Center, has received two grants worth more than $600,000 combined to further develop artificial intelligence (AI) to help diagnose and monitor glaucoma.
Source: EurekAlert! - Medicine and Health - September 17, 2020 Category: International Medicine & Public Health Source Type: news

Upstate researcher awarded $2.7 million in grants to research eye scarring, glaucoma
One of the grants expands Dr. Audrey Bernstein ’s ongoing NIH-funded work, which is focused on developing a therapeutic target for scarring in the eye in conjunction with biotech collaborators.
Source: SUNY Upstate Medical - August 12, 2020 Category: Universities & Medical Training Tags: News Source Type: news

Professor wins $300,000 Research to Prevent Blindness Award
Grant will support Samuel Herberg ’s glaucoma research.
Source: SUNY Upstate Medical - November 21, 2019 Category: Universities & Medical Training Tags: News Source Type: news