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Infectious Disease: Cytomegalovirus

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Total 111 results found since Jan 2013.

Unilateral acute iris transillumination syndrome with glaucoma and iris pigment epithelium dispersion simulating iris melanoma
CONCLUSION AND IMPORTANCE: Unilateral acute iris transillumination syndrome with diffuse iris pigment epithelial loss can simulate iris melanoma. Prompt herpes viral studies may be informative.PMID:37680309 | PMC:PMC10481171 | DOI:10.1016/j.ajoc.2023.101912
Source: Herpes - September 8, 2023 Category: Infectious Diseases Authors: Orlando G Gonzalez Martinez Carol L Shields Jerry A Shields Patricia Ch évez-Barrios Debbie Rigney Walley Ralph C Eagle Tatyana Milman Source Type: research

Clinical differences between Posner-Schlossman syndrome patients with intermittent intraocular pressure elevation and glaucomatous damage
CONCLUSION: Distinctive characteristics existed between PSS patients with secondary glaucoma and those with intermittent IOP elevation. Compound trabeculectomy appears to be an effective treatment option when IOP cannot be controlled through topical medications.PMID:37634490 | DOI:10.1159/000533495
Source: Cell Research - August 27, 2023 Category: Cytology Authors: Qian Wang Wen Zeng Weijuan Zeng Yang Liu Min Ke Source Type: research

Rare case report: a 26-year-old man with Eales' disease
Conclusion: Despite the aggressive treatment with oral steroids, immunosuppressants, and anti-VEGF injections, there were many exacerbations, and remission was not achieved. As a result, aggressive neovascular glaucoma developed, which led to total blindness in the left eye and legal blindness in the right eye. Abbreviations: HLA = human leukocyte antigens, Anti-VEGF = vascular endothelial growth factor inhibitors, BCVA = best corrected visual acuity, FA = fundus angiography, HBsAg = hepatitis B surface antigen, Anti-HCV = hepatitis C antibodies, TPHA = Treponema Pallidum hemagglutination assay, PCR = polymerase chain reac...
Source: Herpes - July 31, 2023 Category: Infectious Diseases Authors: Sandra Bleidele Igors Solomatins A īda Macijevska Source Type: research

Juvenile Dermatomyositis and Infantile Cerebral Palsy: Aicardi-Gouteres Syndrome, Type 5, with a Novel Mutation in SAMHD1-A Case Report
CONCLUSIONS: Early diagnosis of AGS is highly important as it allows starting treatment in a timely manner. Timely treatment, in return, can help avoid the development/progression of end-organ damage, including severe neurological complications and early death. It is necessary to spread information about AGS among neurologists, neonatologists, infectious disease specialists, and pediatricians. A multidisciplinary team approach is required.PMID:37371788 | DOI:10.3390/biomedicines11061693
Source: Herpes - June 28, 2023 Category: Infectious Diseases Authors: Lubov S Sorokina Rinat K Raupov Mikhail M Kostik Source Type: research

Janssen to Highlight Scientific Advances and Commitment to Transform Cancer Care at ASCO and EHA with More than 90 Presentations Showcasing Robust, Differentiated Portfolio and Pipeline in Hematologic Malignancies and Solid Tumors
This study evaluates an investigational combination regimen of IMBRUVICA® (ibrutinib) plus venetoclax (I+V) for newly diagnosed chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), (Abstracts #7535 and #P617, respectively).Advancing the Science of Solid Tumors Through Precision MedicineJanssen’s continued innovation in solid tumors focuses on advancing precision medicine options for patients with biomarker-driven disease who have limited targeted treatment options and moving patients into earlier lines of therapy when treatments may be more effective. Lung CancerAn oral presentation will report ...
Source: Johnson and Johnson - May 18, 2023 Category: Pharmaceuticals Tags: Innovation Source Type: news

Murine cytomegalovirus localization and uveitic cell infiltration might both contribute to trabecular meshwork impairment in Posner-Schlossman syndrome: Evidence from an open-angle rat model
Exp Eye Res. 2023 May 1:109477. doi: 10.1016/j.exer.2023.109477. Online ahead of print.ABSTRACTAs a special type of glaucoma, Posner-Schlossman syndrome (PSS) is characterized by elevated intraocular pressure (IOP) and anterior uveitis. Cytomegalovirus (CMV) anterior chamber infection has now been considered the leading cause of PSS. We used murine CMV (MCMV) intracameral injection to establish a rat model manifested in IOP elevation and mild anterior uveitis, much like PSS; viral localization and gene expression at various time points and inflammatory cell infiltration derived from innate and adaptive immunity were invest...
Source: Cell Research - May 3, 2023 Category: Cytology Authors: Qilian Sheng Yanan Sun Ruyi Zhai Xintong Fan Yue Ying Zhijun Liu Xiangmei Kong Source Type: research

Long-Term Surgical Outcomes and Possible Postoperative Complication with Severe Corneal Endothelial Cell Loss After Trabeculectomy for Cytomegalovirus-Associated Anterior Uveitis with Secondary Glaucoma
CONCLUSION: Trabeculectomy effectively controlled IOP in CMV-SG, but attention must be paid to corneal endothelial cell loss.PMID:37093974 | DOI:10.1080/09273948.2023.2197497
Source: Ocular Immunology and Inflammation - April 24, 2023 Category: Allergy & Immunology Authors: Masaaki Yoshida Yu Yokoyama Taiki Kokubun Satoru Tsuda Noriko Himori Shigeto Maekawa Shunji Yokokura Takehiro Hariya Wataru Kobayashi Kazuki Hashimoto Toru Nakazawa Source Type: research