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Therapy: Corticosteroid Therapy

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Total 364 results found since Jan 2013.

Intravitreal fluocinolone acetonide 0.19  mg (ILUVIEN®) in patients with non-infectious uveitis: real-world effectiveness and safety outcomes at 12 months
ConclusionThe FAc implant is safe and effective at treating NIU over 12  months in a real-world setting in Spain.
Source: International Ophthalmology - September 12, 2023 Category: Opthalmology Source Type: research

New Concepts in Steroid Glaucoma
AbstractPurpose of ReviewIn this article, we discuss the pathophysiology underlying intraocular pressure elevation associated with corticosteroid use as well as targeted therapies for treatment.Recent FindingsSeveral signaling pathways at the level of the trabecular meshwork are altered by steroid exposure. A pre-existing diagnosis of glaucoma is the best-established risk factor for development of steroid-associated ocular hypertension. Topical, local, and systemic steroids have all been associated with ocular hypertension.SummaryCurrent management is directed at steroid-sparing alternatives to treatment, steroid cessation...
Source: Current Ophthalmology Reports - August 23, 2023 Category: Opthalmology Source Type: research

Rare case report: a 26-year-old man with Eales' disease
Conclusion: Despite the aggressive treatment with oral steroids, immunosuppressants, and anti-VEGF injections, there were many exacerbations, and remission was not achieved. As a result, aggressive neovascular glaucoma developed, which led to total blindness in the left eye and legal blindness in the right eye. Abbreviations: HLA = human leukocyte antigens, Anti-VEGF = vascular endothelial growth factor inhibitors, BCVA = best corrected visual acuity, FA = fundus angiography, HBsAg = hepatitis B surface antigen, Anti-HCV = hepatitis C antibodies, TPHA = Treponema Pallidum hemagglutination assay, PCR = polymerase chain reac...
Source: Herpes - July 31, 2023 Category: Infectious Diseases Authors: Sandra Bleidele Igors Solomatins A īda Macijevska Source Type: research

Intraocular pressure elevation and intravitreal steroid implant injection: State of the art in 2023. Recommendations of the French Glaucoma Society and French Ophthalmology Society French version
J Fr Ophtalmol. 2023 Jul 20:S0181-5512(23)00287-5. doi: 10.1016/j.jfo.2023.05.003. Online ahead of print.ABSTRACTThese are the recommendations of French glaucoma and retina experts on the management of ocular hypertension (OHT) observed in 1/3 of cases after intravitreal steroid implant injections. They are an update to the recommendations first published in 2017. There are two implants on the French market: the dexamethasone (DEXi) and fluocinolone acetonide (FAci) implants. It is important to know the pressure status before injecting a patient with a steroid implant. Monitoring of the IOP adapted to the specific drug is ...
Source: Journal Francais d Ophtalmologie - July 22, 2023 Category: Opthalmology Authors: C Dot M Poli F Aptel A Labbe L Kodjikian S Baillif B Bodaghi P Denis Source Type: research

Retinoprotective compounds, current efficacy, and future prospective
Neural Regen Res. 2023 Dec;18(12):2619-2622. doi: 10.4103/1673-5374.373662.ABSTRACTRetinal dysfunction is the most common cause of vision loss in several retinal disorders. It has been estimated a great increase in these pathologies that are becoming more globally widespread and numerous over time, also supported by the life expectancy increment. Among different types of retinopathies, we can account some that share causes, symptoms, and treatment including diabetic retinopathy, age-related macular degeneration, glaucoma, and retinitis pigmentosa. Molecular changes, environmental factors, and genetic predisposition might b...
Source: Cell Research - July 14, 2023 Category: Cytology Authors: Rachele Marino Rebecca Sappington Marco Feligioni Source Type: research

2% Ganciclovir Controlled Posner-Schlossman Syndrome Relapse and Reduced the Chance of Corticosteroid Dependence: A Large Cohort in East China
CONCLUSION: 2% GCV solutions worked effectively on PSS relapse with corticosteroids and anti-glaucoma agents. In patients suspected of CMV infection, proper GCV could reduce the chance of corticosteroid dependence.PMID:37437131 | DOI:10.1080/09273948.2023.2228404
Source: Ocular Immunology and Inflammation - July 12, 2023 Category: Allergy & Immunology Authors: Qilian Sheng Yanan Sun Ruyi Zhai Xintong Fan Yue Ying Xiangmei Kong Source Type: research

Juvenile Dermatomyositis and Infantile Cerebral Palsy: Aicardi-Gouteres Syndrome, Type 5, with a Novel Mutation in SAMHD1-A Case Report
CONCLUSIONS: Early diagnosis of AGS is highly important as it allows starting treatment in a timely manner. Timely treatment, in return, can help avoid the development/progression of end-organ damage, including severe neurological complications and early death. It is necessary to spread information about AGS among neurologists, neonatologists, infectious disease specialists, and pediatricians. A multidisciplinary team approach is required.PMID:37371788 | DOI:10.3390/biomedicines11061693
Source: Herpes - June 28, 2023 Category: Infectious Diseases Authors: Lubov S Sorokina Rinat K Raupov Mikhail M Kostik Source Type: research

Current practice in the management of ocular toxoplasmosis
Conclusion Our report presents a current management approach for ocular toxoplasmosis, as practised by a large international group of uveitis-specialised ophthalmologists.
Source: British Journal of Ophthalmology - June 22, 2023 Category: Opthalmology Authors: Yogeswaran, K., Furtado, J. M., Bodaghi, B., Matthews, J. M., International Ocular Toxoplasmosis Study Group, Smith, J. R., Accorinti, Agarwal, Agarwal, Ahn, Akyol, Alvarez, Amer, Androudi, Arcinue, Arellanes-Garcia, Fernando Arevalo, Arrieta-Bechara, Art Tags: Original articles - Clinical science Source Type: research

Ocular hypertension and intravitreal steroids injections, update in 2023. French guidelines of the French glaucoma society and the French ophthalmology society
J Fr Ophtalmol. 2023 Jun 9:S0181-5512(23)00246-2. doi: 10.1016/j.jfo.2023.05.001. Online ahead of print.ABSTRACTThese guidelines are a consensus of French glaucoma and retina experts on the management of ocular hypertension (OHT) observed in a third of the cases after corticosteroid implant intravitreal injections. They update the first guidelines published in 2017. Two implants are marketed in France: the dexamethasone implant (DEXi) and the fluocinolone acetonide implant (FAci). It is essential to assess the pressure status before injecting a patient with a corticosteroid implant. A molecule-specific monitoring of the in...
Source: Journal Francais d Ophtalmologie - June 11, 2023 Category: Opthalmology Authors: C Dot M Poli F Aptel A Labbe L Kodjikian S Baillif B Bodaghi P Denis Source Type: research