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Total 442 results found since Jan 2013.

Incidence of thromboembolic events after use of gelatin-thrombin-based hemostatic matrix during intracranial tumor surgery
This study evaluates the relationship between flowable hemostatic matrix and deep vein thrombosis in a large cohort of patients treated for brain tumor removal. The authors conducted a retrospective, multicenter, clinical review of all craniotomies for tumor removal performed between 2013 and 2014. Patients were classified in three groups: group I (flowable gelatin hemostatic matrix with thrombin), group II (gelatin hemostatic without thrombin), and group III (classical hemostatic). A total of 932 patients were selected: tumor pathology included 441 gliomas, 296 meningiomas, and 195 metastases. Thromboembolic events were i...
Source: Neurosurgical Review - April 24, 2017 Category: Neurosurgery Source Type: research

A Method for Minimizing Rotational Errors of Implant Prostheses.
CONCLUSION: The CW-Hs method was found to be the most suitable for minimizing rotational error between implants and analogs. PMID: 28518184 [PubMed - as supplied by publisher]
Source: International Journal of Oral and Maxillofacial Implants - May 19, 2017 Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research

The education of a surgeon
The Education of a Surgeon is one surgeon's view of how medicine has progressed through several centuries. However, one problem is that it does not mention several major events, including Medicare. Also, some paragraphs seem written expressly for the nonphysician, whereas others clearly require medical education. Some heroes go unnamed or ignored. The importance of the hemostat is noted, but not that it was made practical by Jules- Émile Péan who introduced a toothed locking mechanism in the handle.
Source: Journal of Pediatric Surgery - May 24, 2017 Category: Surgery Authors: Michael D. Klein Tags: Book Review Source Type: research

Slug slime inspires new surgical glue
(Reuters) – Scientists have developed an experimental surgical glue inspired by the mucus secreted by slugs that could offer an alternative to sutures and staples for closing wounds. While some medical glues already exist, they often adhere weakly, are not particularly flexible and frequently cannot be used in very wet conditions. To get around those problems, a group of scientists from Harvard and other research centers decided to learn from slugs, which – as well as making slime to glide on – can produce extremely adhesive mucus as a defense mechanism. The slugs’ trick is to generate a substance t...
Source: Mass Device - July 28, 2017 Category: Medical Devices Authors: MassDevice Tags: Research & Development Surgical Wound Care Source Type: news

How slugs are creating better medical adhesives
[Image from Jianya Li, Adam D. Celiz, David J. Mooney]Slug mucus is the inspiration behind a new adhesive to close surgical wounds and reduce the use of surgical staples, according to new research out of Harvard. Some of the current adhesives on the market can be toxic and stick together tissues weakly. Some can’t be used in wet environments altogether, which can pose a problem for closing tissues in the body. Harvard University engineering researcher Jianya Li and his team used the defensive mucus secreted by slugs to develop a surgical glue that addresses the challenges associated with previous adhesives. Li and his te...
Source: Mass Device - August 4, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Research & Development Surgical hemostat MedTech surgical adhesive Source Type: news

J & J ’ s Ethicon launches ProxiSure laparoscopic suturing device
Johnson & Johnson (NYSE:JNJ) subsidiary Ethicon said today it launched the ProxiSure laparoscopic suturing device. Ethicon said the device features its endomechanical, suture and curved needle technologies to improve suturing precision in tight spaces. The device allows surgeons to reach desired angles, control bites and secure nots during suturing and knot tying to reduce the risk of needle loss, the company added. “With the patient’s health at the forefront of our thinking, we aimed to introduce a suturing device that will help reduce the margin of error in minimally-invasive surgery. Surgeons will now b...
Source: Mass Device - August 21, 2017 Category: Medical Devices Authors: Fink Densford Tags: Blog Ethicon johnsonandjohnson Source Type: news

Zeolite ‐loaded alginate‐chitosan hydrogel beads as a topical hemostat
Abstract Hemorrhage is the leading cause of preventable death after a traumatic injury, and the largest contributor to loss of productive years of life. Hemostatic agents accelerate hemostasis and help control hemorrhage by concentrating coagulation factors, acting as procoagulants and/or interacting with erythrocytes and platelets. Hydrogel composites offer a platform for targeting both mechanical and biological hemostatic mechanisms. The goal of this work was to develop hydrogel particles composed of chitosan, alginate, and zeolite, and to assess their potential to promote blood coagulation via multiple mechanisms: eryth...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - August 26, 2017 Category: Materials Science Authors: Parinaz Fathi, Michael Sikorski, Katerina Christodoulides, Kristen Langan, Yoon Sun Choi, Michael Titcomb, Anjali Ghodasara, Omasiri Wonodi, Hemi Thaker, Mert Vural, Adam Behrens, Peter Kofinas Tags: Original Research Report Source Type: research

Vascular Trauma Revisited
Trauma with bleeding from named vessels has been treated since antiquity. Many of the techniques used in the modern era to control bleeding such as manual compression, cauterization, and proximal and distal ligatures were described before 1000 AD. Even the earliest version of a hemostat, Ambrose Pare ’s “Bec de Corbin”, was described in the 1500s.
Source: Journal of the American College of Surgeons - August 30, 2017 Category: Surgery Authors: David V. Feliciano Tags: Scudder Oration on Trauma Source Type: research

Selective Stimulation of Facial Muscles Following Chronic Intraneural Electrode Array Implantation and Facial Nerve Injury in the Feline Model
Conclusion: We have established in the animal model the ability of a chronically implanted MEA to selectively stimulate restricted FN fiber populations and elicit activations in specific facial muscles. Likewise, after FN injury, selective stimulation of restricted FN fiber populations and subsequent activation of discrete facial muscles can be achieved after acute MEA implantation.
Source: Otology and Neurotology - September 16, 2017 Category: ENT & OMF Tags: Basic Science Source Type: research

Wrist Arthroscopy Under Portal Site Local Anesthesia Without Tourniquet and Sedation
We had developed the technique of portal site local anaesthesia (PSLA) for wrist arthroscopy. Two percent lidocaine with 1:200,000 epinephrine is injected through a 25G needle to various portal sites. The radiocarpal joint is then distended with saline injection and portal is created with transverse superficial skin incision followed by dilation with curved hemostat. The patient is neither sedated, nor under general or regional anaesthesia. Tourniquet is not routinely used. PSLA can achieve satisfactory comfort level in 88% of our 111 patients without any complication. In well-selected patients, it is a safe and comfortable procedure.
Source: Hand Clinics - October 7, 2017 Category: Orthopaedics Authors: Siu-cheong Jeffrey Justin Koo, Pak-cheong Ho Source Type: research

Comparison of 2 modified methods for the active removal of silicone oil with a 23-gauge transconjunctival vitrectomy system
Abstract To report and compare 2 modified approaches for the active removal of silicone oil (ROSO) with a 23-gauge transconjunctival vitrectomy system. This prospective single blinded study was conducted from January 2015 to December 2016. Eighty-nine eyes of 86 patients who underwent silicone oil removal were enrolled. Patients were randomly divided into either group A or B. In group A, the fluid–air exchange tube was connected to a 1 mL syringe with the plunger removed and the tip was dilated with a hemostat so that it fit into the cap of the 23-gauge cannula to form a seal for oil drainage. In group B, the tip of t...
Source: Medicine - October 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Excision of sebaceous cyst by intraoral approach: A case report
Rationale: Surgical removal of a sebaceous cyst is usually accomplished through an external incision, which inevitably results in a scar. Herein, we described an intraoral approach for excising sebaceous cysts located in the lip or cheek near lip commissure, to avoid a skin scar. Patient concerns: Removal of the cyst but without leaving a scar on the face. Diagnoses: Six patients were diagnosed with a subcutaneous cyst located in the lip or cheek near lip commissure. Interventions: We implemented an intraoral approach to excise the cyst, wherein an intraoral incision was made and blunt dissection was performed t...
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Porous chitosan microspheres containing zinc ion for enhanced thrombosis and hemostasis
Publication date: 1 April 2018 Source:Materials Science and Engineering: C, Volume 85 Author(s): Meng Pan, Zonghao Tang, Jianbing Tu, Zhengchao Wang, Qinhui Chen, Rongdong Xiao, Haiqing Liu Quick hemostats for non-lethal massive traumatic bleeding in battlefield and civilian accidents are important for reducing mortality and medical costs. Chitosan (CS) has been widely used as a clinic hemostat. To enhance its hemostatic efficiency, Zn2+ in the form of zinc alginate (ZnAlg) was introduced to CS to make porous CS@ZnAlg microspheres with ZnAlg component on the surface. Such microspheres were prepared by successive steps of ...
Source: Materials Science and Engineering: C - December 19, 2017 Category: Materials Science Source Type: research

Potent Hemostatic Efficacy of a Novel Recombinant Fibrin Sealant Patch (KTF-374) in Rabbit Bleeding Models.
CONCLUSIONS: These results suggest that KTF-374 possesses more potent hemostatic properties than FCCF for various patterns of bleeding. KTF-374 is a promising hemostat due to its potent efficacy and good visibility of the wound site through the patch. PMID: 29260920 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - December 22, 2017 Category: Surgery Tags: J Invest Surg Source Type: research

Baxter buys Mallinckrodt ’ s Recothrom, Preveleak sealants for $153m
Baxter (NYSE:BAX) said today it inked an agreement with Mallinckrodt Pharmaceuticals (NYSE:MNK) to acquire its Recothrom and Preveleak hemostat and sealant products for approximately $153 million up front with a potential for contingent payments in the future. Mallinckrodt’s Recothorm is a stand-alone recombinant thrombin-based product with indications as an aid to hemostasis to control oozing blood and minor bleeding from capillaries and small venules when control of bleeding by standard surgical techniques is ineffective or impractical. The Preveleak sealant is designed to seal suture holes during surgical repai...
Source: Mass Device - January 8, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Surgical Baxter Mallinckrodt Source Type: news