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Two cases of extensively drug-resistant (XDR) < em > Neisseria gonorrhoeae < /em > infection combining ceftriaxone-resistance and high-level azithromycin resistance, France, November 2022 and May 2023
We report two extensively drug-resistant (XDR) Neisseria gonorrhoeae (NG) isolates combining high-level resistance to azithromycin and resistance to ceftriaxone, obtained in France from two heterosexual patients, one of whom returned from Cambodia. Whole genome sequencing identified MLST ST16406, the mosaic penA-60.001 which caused ceftriaxone resistance in the internationally spreading FC428 clone, and the A2059G mutation in the 23S rRNA gene. The NG isolates F93 and F94 were related to XDR isolates detected in Austria and the United Kingdom in 2022.PMID:37707979 | DOI:10.2807/1560-7917.ES.2023.28.37.2300456
Source: Euro Surveill - September 14, 2023 Category: Infectious Diseases Authors: Clara Maubaret Fran çois Caméléna Manel Mrim èche Aymeric Braille Mathilde Liberge Mary Mainardis Cl émence Guillaume Franck Noel C écile Bébéar Jean-Michel Molina Florence Lot Emilie Chazelle B éatrice Berçot Source Type: research
Normative Data for the Alternating and Orthographic Constraint Semantic Fluency Tests in the Adult French-Quebec Population and Validation Study in Mild Cognitive Impairment and Alzheimer's Disease
Arch Clin Neuropsychol. 2023 Sep 14:acad065. doi: 10.1093/arclin/acad065. Online ahead of print.ABSTRACTVerbal fluency tests, known to elicit executive functions (EFs), have proven useful in distinguishing healthy individuals from those with cognitive impairment. The present study addresses two new tests of verbal fluency that elicit EFs, namely, extradimensional alternating fluency (EAF) and extradimensional orthographic constraint semantic fluency (EOCSF). The aim of Study 1 was to provide normative data in the adult and elderly population of French Québec for the two fluency tests. The aim of Study 2 was to determine t...
Source: Archives of Clinical Neuropsychology - September 14, 2023 Category: Psychiatry & Psychology Authors: Jo ël Macoir Carol Hudon Source Type: research
Two cases of extensively drug-resistant (XDR) < em > Neisseria gonorrhoeae < /em > infection combining ceftriaxone-resistance and high-level azithromycin resistance, France, November 2022 and May 2023
We report two extensively drug-resistant (XDR) Neisseria gonorrhoeae (NG) isolates combining high-level resistance to azithromycin and resistance to ceftriaxone, obtained in France from two heterosexual patients, one of whom returned from Cambodia. Whole genome sequencing identified MLST ST16406, the mosaic penA-60.001 which caused ceftriaxone resistance in the internationally spreading FC428 clone, and the A2059G mutation in the 23S rRNA gene. The NG isolates F93 and F94 were related to XDR isolates detected in Austria and the United Kingdom in 2022.PMID:37707979 | DOI:10.2807/1560-7917.ES.2023.28.37.2300456
Source: Euro Surveill - September 14, 2023 Category: Infectious Diseases Authors: Clara Maubaret Fran çois Caméléna Manel Mrim èche Aymeric Braille Mathilde Liberge Mary Mainardis Cl émence Guillaume Franck Noel C écile Bébéar Jean-Michel Molina Florence Lot Emilie Chazelle B éatrice Berçot Source Type: research
Navigating carbon emissions in G-7 economies: a quantile regression analysis of environmental-economic interplay
This study employs panel data from 1990 to 2020 for the G-7 countries (Canada, France, Germany, Italy, Japan, the UK, and the USA) and employs the examination of heterogeneous slope coefficients and cross-sectional dependence tests as preliminary steps before conducting cointegration analysis and second-generation unit-root tests. This study employs the method of movement quantile regression (MMQR) to analyze long-run and short-run relationships. The findings from the MMQR model indicate that economic growth and imports have a negative impact on consumption-based CO2 (CCO2) emissions, which worsens at higher quantiles. On ...
Source: Environmental Science and Pollution Research International - September 14, 2023 Category: Environmental Health Authors: Bowen Luo Arshad Ahmad Khan Xiaoming Wu Hongxia Li Source Type: research
What altitude is safe for infants? An expert panel survey
CONCLUSION: This survey revealed a certain consensus about the maximum travel altitude to be recommended for infants.PMID:37704526 | DOI:10.1016/j.arcped.2023.06.011
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Corentin Tann é Blandine Peyret Sophia Cherif-Alami Manon Navarre Isabelle Pruvost Marie-H élène Said Marie Baret Estelle Le Fur Am élie Basso Sarah Bonnet-Ducrot Cecile Desbruyeres Guillaume Mortamet Source Type: research
Clinics dedicated to transition preparation for adolescents and young adults with chronic conditions: Factors influencing their use
Arch Pediatr. 2023 Sep 11:S0929-693X(23)00144-6. doi: 10.1016/j.arcped.2023.08.004. Online ahead of print.ABSTRACTTo pool resources and reduce inequalities in access to transition preparation for patients, transition clinics were created in France. They are places in hospitals, independent of the usual care departments, offering multiple resources and services for adolescents and their parents. Of the 24 physicians from care departments who were surveyed, half of them do not use transition clinics. The implementation of transition clinics in hospitals did not lead to their adoption by the care departments that needed the m...
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Enora Le Roux Aur élie Bourmaud Paul Jacquin Nizar Mahlaoui Aur élien Guffroy Alexandre Belot M élanie Romier Jane Sattoe AnneLoes Van Staa Corinne Alberti H élène Mellerio Agn ès Dumas Source Type: research
Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels
CONCLUSIONS: Novel loss-of-function mutations in DLK1 gene were identified in two French girls with CPP. Additionally, we demonstrated a pattern of dynamic changes in circulating DLK1 serum levels in humans and mice during pubertal stages, reinforcing the role of this factor in pubertal timing.PMID:37703313 | DOI:10.1093/ejendo/lvad129
Source: European Journal of Endocrinology - September 13, 2023 Category: Endocrinology Authors: Luciana Montenegro Carlos Seraphim Fl ávia Tinano Maiara Piovesan Ana P M Canton Ken McElreavey Severine Brabant Natalia P Boris Melissa Magnuson Rona S Carroll Ursula B Kaiser Jes ús Argente Vicente Barrios Vinicius N Brito Raja Brauner Ana Claudia Lat Source Type: research
Kinetics of metal and metalloid concentrations in holopelagic Sargassum reaching coastal environments
This study measures the kinetics of metal trace elements (MTE) in Sargassum reaching different coastal environments. In July 2021, over a period of 25 days, fixed experimental floating cages containing the three Sargassum morphotypes (S. fluitans III and S. natans I and VIII) were placed in three different coastal habitats (coral reef, seagrass, and mangrove) in Guadeloupe (French West Indies). Evolution of biomasses and their total phenolic content of Sargassum reveals that environmental conditions of caging were stressful and end up to the death of algae. Concentrations of 19 metal(loid) trace elements were analyzed and ...
Source: Environmental Science and Pollution Research International - September 13, 2023 Category: Environmental Health Authors: Oc éanne-Amaya Cipolloni Magalie Baudrimont Beno ît Simon-Bouhet Émilie Pauline Dassié Julien Gigault Sol ène Connan Pierre-Yves Pascal Source Type: research
Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels
CONCLUSIONS: Novel loss-of-function mutations in DLK1 gene were identified in two French girls with CPP. Additionally, we demonstrated a pattern of dynamic changes in circulating DLK1 serum levels in humans and mice during pubertal stages, reinforcing the role of this factor in pubertal timing.PMID:37703313 | DOI:10.1093/ejendo/lvad129
Source: European Journal of Endocrinology - September 13, 2023 Category: Endocrinology Authors: Luciana Montenegro Carlos Seraphim Fl ávia Tinano Maiara Piovesan Ana P M Canton Ken McElreavey Severine Brabant Natalia P Boris Melissa Magnuson Rona S Carroll Ursula B Kaiser Jes ús Argente Vicente Barrios Vinicius N Brito Raja Brauner Ana Claudia Lat Source Type: research
What altitude is safe for infants? An expert panel survey
CONCLUSION: This survey revealed a certain consensus about the maximum travel altitude to be recommended for infants.PMID:37704526 | DOI:10.1016/j.arcped.2023.06.011
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Corentin Tann é Blandine Peyret Sophia Cherif-Alami Manon Navarre Isabelle Pruvost Marie-H élène Said Marie Baret Estelle Le Fur Am élie Basso Sarah Bonnet-Ducrot Cecile Desbruyeres Guillaume Mortamet Source Type: research
Clinics dedicated to transition preparation for adolescents and young adults with chronic conditions: Factors influencing their use
Arch Pediatr. 2023 Sep 11:S0929-693X(23)00144-6. doi: 10.1016/j.arcped.2023.08.004. Online ahead of print.ABSTRACTTo pool resources and reduce inequalities in access to transition preparation for patients, transition clinics were created in France. They are places in hospitals, independent of the usual care departments, offering multiple resources and services for adolescents and their parents. Of the 24 physicians from care departments who were surveyed, half of them do not use transition clinics. The implementation of transition clinics in hospitals did not lead to their adoption by the care departments that needed the m...
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Enora Le Roux Aur élie Bourmaud Paul Jacquin Nizar Mahlaoui Aur élien Guffroy Alexandre Belot M élanie Romier Jane Sattoe AnneLoes Van Staa Corinne Alberti H élène Mellerio Agn ès Dumas Source Type: research
Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1)
CONCLUSION: In the context of CRT for LAVC, the present study reports encouraging results even if there is clearly room for further improvements, in terms of both treatment outcomes, toxicity and treatment interruption management.PMID:37700153 | DOI:10.1007/s11547-023-01712-8
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Gabriella Macchia Valentina Lancellotta Martina Ferioli Calogero Cas à Donato Pezzulla Brigida Pappalardi Concetta Laliscia Edy Ippolito Jacopo Di Muzio Alessandra Huscher Francesca Tortoreto Mariangela Boccardi Roberta Lazzari Anna Myriam Perrone France Source Type: research
Epidemiology of Spinocerebellar Ataxias in Europe
Cerebellum. 2023 Sep 12. doi: 10.1007/s12311-023-01600-x. Online ahead of print.ABSTRACTSpinocerebellar ataxias (SCAs) are a heterogenous group of rare neurodegenerative conditions sharing an autosomal dominant pattern of inheritance. More than 40 SCAs have been genetically determined. However, a systematic review of SCA epidemiology in Europe is still missing. Here we performed a narrative review of the literature on the epidemiology of the most common SCAs in Europe. PubMed, Embase, and MEDLINE were searched from inception until 1 April 2023. All English peer-reviewed articles published were considered and then filtered ...
Source: Cerebellum - September 12, 2023 Category: Neuroscience Authors: Filippo De Mattei Fabio Ferrandes Salvatore Gallone Antonio Canosa Andrea Calvo Adriano Chi ò Rosario Vasta Source Type: research
