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Specialty: Cancer & Oncology
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Total 126553 results found since Jan 2013.
Comparison of Effectiveness of Moringa Oleifera Leaves Extract Gel (2%) with Retino A (0.1%) Cream for Treatment of Oral Leukoplakia: Double Blinded Randomized Control Trial
CONCLUSION: This study showed that M. oleifera mucoadhesive gel (2%) is an effective and safe treatment option for oral leukoplakia patients. It demonstrated a significant reduction in lesion size compared to Retino-A cream (0.1%) after 3 months of therapy, without any reported adverse effects. However, long-term follow-up studies are needed to evaluate its long-term effectiveness. The potent antioxidant property of M. oleifera makes it a promising candidate for further studies with concentration variations and in other potentially malignant oral disorders, such as lichen planus and OSMF. The development of chemotherapeuti...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Sulem Ansari Shivayogi Charantimath Anabelle Fernandes Jayraj B Malik Prashanth Panta Source Type: research
The Role of En Bloc Resection in the Modern Era for Primary Spine Tumors
CONCLUSION: Choosing the optimal approach to primary spine tumors is complex. A comprehensive and up-to-date assessment of the evidence is required to guide patient care and to balance the often-competing goals of prolonging life and preserving quality of life.PMID:37732462 | DOI:10.1097/BRS.0000000000004821
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Caleb M Yeung Mark Bilsky Patrick J Boland Max Vaynrub Source Type: research
Benefits beyond cardiometabolic health: the potential of frequent high intensity 'exercise snacks' to improve outcomes for those living with and beyond cancer
J Physiol. 2023 Sep 21. doi: 10.1113/JP284985. Online ahead of print.ABSTRACTHigh intensity interval training (HIIT) has been shown to consistently elicit rapid and significant adaptations in a number of physiological systems, across many different healthy and clinical populations. In addition, there is increasing interest in how some acute, yet transient responses to high intensity exercise potentially reduce the risks of particular diseases. Recent work has shown that discrete, brief bouts of high intensity exercise (termed 'exercise snacks') can improve glucose control and vascular health and thus counter the negative c...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: David G Jenkins James L Devin Kathryn L Weston Joseph G Jenkins Tina L Skinner Source Type: research
Unique Considerations in Early Detection, Risk, and Awareness of Endometrial Cancer in Black Women
Cancer Control. 2023 Jan-Dec;30:10732748231202952. doi: 10.1177/10732748231202952.ABSTRACTEndometrial cancer is the most common gynecologic cancer in the United States. Over the last several decades, the incidence of aggressive tumors, and thus the rate of death from disease, has increased significantly. The population most affected by these epidemiologic shifts are Black women. Symptom awareness, lack of treatment access, and failure of providers to provide guideline-concordant care are just some of the drivers behind these changes. Race as a social construct has historically categorized women into groups that are not ref...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Matthew Schlumbrecht Kallia Wright Sophia George Source Type: research
Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
CONCLUSION: Th22, Th17, Th1, and Th2 subsets may play an essential role in BC patients. Th22, Th17, Th1, and Th2 cells may have potential significance to be used as clinical markers in BC patients with different molecular classification. Th22 cells may have potential value in BC patients' outcomes prediction, providing clinical value.PMID:37732365 | DOI:10.1111/1759-7714.15119
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Zhiguo Peng Xinyue Dong Miao He Yajing Zhao Yujia Liu Mo Li Guosheng Li Xiuwen Wang Li Li Yu Hu Source Type: research
Is cervical dysplasia a major concern in women with inflammatory bowel disease? A Spanish retrospective study
Rev Esp Enferm Dig. 2023 Sep 21. doi: 10.17235/reed.2023.9890/2023. Online ahead of print.ABSTRACTCervical cancer (CC) is the fourth most common cancer affecting women worldwide. The risk of women immunosuppressed due to AIDS or organ transplantation is well documented, as most cases are caused by persistent human papillomavirus (HPV) infection and immunosuppression can prevent clearing HPV. Although European guidelines advise that inflammatory bowel disease (IBD) women under immunosuppression should be screened for CC as regularly as high-risk patients, quality evidence is lacking in our country. We performed a retrospect...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lorena Jara Fern ández Juan Ángel Ferrer Jos é Lázaro Pérez Calle Pilar L ópez Serrano Source Type: research
Boiling histotripsy induces dendritic cell activation and acquisition of antigen in tumor draining lymph nodes
bioRxiv. 2023 Sep 6:2023.09.02.552844. doi: 10.1101/2023.09.02.552844. Preprint.ABSTRACTBoiling histotripsy (BH), a mechanical focused ultrasound ablation strategy, can elicit intriguing signatures of anti-tumor immunity. However, the influence of BH on dendritic cell function is unknown, compromising our ability to optimally combine BH with immunotherapies to control metastatic disease. Here, by applying BH to B16F10 melanoma expressing a ZsGreen antigen in a monotherapy protocol that elicits abscopal tumor control, we observed a marked increase in antigen acquisition by multiple phagocytic immune cells, including convent...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Eric A Thim Lydia E Petricca F átima Rivera-Escalera Alexander S Mathew Michael R Elliott Timothy N J Bullock Richard J Price Source Type: research
Restoring Balance: a physical activity intervention for Native American cancer survivors and their familial support persons
CONCLUSION: Exercise improved cardiorespiratory fitness and physical function among Native American cancer survivors and familial supporters. A longer intervention may influence other important health outcomes among Native American survivors. Additional improvements demonstrated among Native American family members may have a meaningful impact on cancer prevention in this underserved population with shared heritable and environmental risks.PMID:37731941 | PMC:PMC10508873 | DOI:10.1249/esm.0000000000000007
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Jennifer W Bea Hendrik 'Dirk' de Heer Taylor Lane Brenda Charley Etta Yazzie Janet Yellowhair Jennifer Hudson Brian Kinslow Betsy C Wertheim Denise J Roe Anna Schwartz Source Type: research
Population effectiveness of endoscopy screening for mortality reduction in gastric cancer
CONCLUSIONS: In addition to the effectiveness of the used modality, the disease burden and screened rate were important in the population effectiveness of cancer screening. Regarding the high NNSs and the low expected mortality-rate reduction, population-based endoscopic screening seems not to be effective in many countries, and these results are meaningful in decision-making regarding the introduction of endoscopic screening.PMID:37731836 | PMC:PMC10508325 | DOI:10.1002/deo2.296
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Naoki Ishii Yasutoshi Shiratori Masahiro Ishikane Fumio Omata Source Type: research
Comparison of hepatic arterial infusion chemotherapy with mFOLFOX vs. first-line systemic chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma
Conclusion: Our study revealed that HAIC was a safe and effective therapeutic regimen for unresectable iCCA with better intrahepatic tumor control when compared to SC. Meanwhile, patients with single tumor were more likely to benefit from HAIC than SC.PMID:37731737 | PMC:PMC10508288 | DOI:10.3389/fphar.2023.1234342
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Zhenyun Yang Yizhen Fu Weijie Wu Zili Hu Yangxun Pan Juncheng Wang Jinbin Chen Dandan Hu Zhongguo Zhou Minshan Chen Yaojun Zhang Source Type: research
Lifestyle habits and gastric cancer in an East Asian population: a Mendelian randomization study
CONCLUSIONS: Our study suggests that tea intake may reduce the risk of GC, for which smoking is a potential risk factor. Nevertheless, a larger and more diverse sample size is needed for further validation.PMID:37731647 | PMC:PMC10507616 | DOI:10.3389/fonc.2023.1224753
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Yuegui Tan Zhao Wei Kun Liu Yuzhen Qin Wenqi Hui Source Type: research
Clinical outcomes of ramucirumab plus docetaxel in the treatment of patients with non-small cell lung cancer after immunotherapy: a systematic literature review
CONCLUSIONS: Cumulatively, these results support the combination of ramucirumab plus docetaxel as an effective and safe subsequent therapy for the treatment of patients with metastatic NSCLC with disease progression irrespective of previous ICI treatment.PMID:37731641 | PMC:PMC10507469 | DOI:10.3389/fonc.2023.1247879
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Edward B Garon Carla Visseren-Grul Maria Teresa Rizzo Tarun Puri Suresh Chenji Martin Reck Source Type: research
Effectiveness and safety of Shenqi Fuzheng injection combined with platinum-based chemotherapy for treatment of advanced non-small cell lung cancer: a systematic review and meta-analysis
CONCLUSION: SFI combined with PBC for the treatment of advanced NSCLC improved the ORR, DCR, and quality of life, and reduced the incidence of myelosuppression and gastrointestinal adverse reactions. However, considering the limitations of existing evidence, further verification using high-quality RCTs is required.SYSTEMATIC REVIEW REGISTRATION: https://inplasy.com/inplasy-2022-7-0026, identifier INPLASY202270026.PMID:37731634 | PMC:PMC10507621 | DOI:10.3389/fonc.2023.1198768
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Chenxi Qiao Shuaihang Hu Dandan Wang Kangdi Cao Zhuo Wang Xinyan Wang Xiumei Ma Zheng Li Wei Hou Source Type: research
Serum basic fibroblast growth factor and interleukin-1 β predict the effect of first-line chemotherapy in patients with advanced gastric cancer
CONCLUSION: The FLOT regimen was effective in reducing the serum CEA, CA199, and TPS levels as well as in improving the 1-year survival rate of patients with good tolerability, making it worthy of clinical promotion and application.PMID:37731570 | PMC:PMC10507556 | DOI:10.12998/wjcc.v11.i26.6083
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Li Zheng Li-Hong Gan Ling Yao Bin Li Ya-Qin Huang Fu-Bao Zhang Meng-Qi Kuang Nian Fang Source Type: research
Topical Calcipotriol Plus Imiquimod Immunotherapy for Nonkeratinocyte Skin Cancers
In this study, we demonstrate that topical TSLP cytokine inducers-calcipotriol and retinoic acid-synergize with IMQ to activate CD4+ T-cell immunity against nonkeratinocyte cutaneous malignancies. Topical calcipotriol plus IMQ treatment reduced breast tumor growth compared with calcipotriol or IMQ alone (P < 0.0001). Calcipotriol plus IMQ-mediated tumor suppression was associated with significant infiltration of CD4+ effector T cells in the tumor microenvironment. Notably, topical calcipotriol plus IMQ immunotherapy enabled immune checkpoint blockade therapy to effectively control immunologically cold breast tumors, whi...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Marjan Azin Kenneth H Ngo Jennet Hojanazarova Shadmehr Demehri Source Type: research
