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Specialty: Biochemistry
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Total 114746 results found since Jan 2013.
Conserved structures of ESCRT-III superfamily members across domains of life
Trends Biochem Sci. 2023 Sep 15:S0968-0004(23)00212-8. doi: 10.1016/j.tibs.2023.08.009. Online ahead of print.ABSTRACTStructural and evolutionary studies of cyanobacterial phage shock protein A (PspA) and inner membrane-associated protein of 30 kDa (IM30) have revealed that these proteins belong to the endosomal sorting complex required for transport-III (ESCRT-III) superfamily, which is conserved across all three domains of life. PspA and IM30 share secondary and tertiary structures with eukaryotic ESCRT-III proteins, whilst also oligomerizing via conserved interactions. Here, we examine the structures of bacterial ESCRT-...
Source: Trends in Biochemical Sciences - September 17, 2023 Category: Biochemistry Authors: Lukas Schl össer Carsten Sachse Harry H Low Dirk Schneider Source Type: research
Pheochromocytoma and paraganglioma in children and adolescents
Acta Biochim Pol. 2023 Sep 17. doi: 10.18388/abp.2020_6955. Online ahead of print.ABSTRACTPheochromocytoma (PPC) and paraganglioma (PGL) are the tumors that rarely occur in the pediatric population (PPGL). Both originate from chromaffin cells, pheochromocytoma is localized in the adrenal gland, whereas paragangliomas are regarded as the tumors present in other localizations, from head to the pelvis. The clinical image is characterized by the presence of the sustained hypertension, headaches, sweating, palpitations. The symptoms are caused by the catecholamine secretion or are related to tumor mass pressure on different org...
Source: Acta Biochim Pol - September 17, 2023 Category: Biochemistry Authors: Teresa Stachowicz-Stencel Natalia Pasikowska Anna Synakiewicz Source Type: research
Impact of diet modification on body mass and kidney function in patients with diabetic nephropathy: a pilot study
CONCLUSIONS: The study shows that obesity is a common comorbid disease in patients with DN and that dietary intervention is associated with a significant reduction in body mass and stabilization of eGFR in these patients.PMID:37717272 | DOI:10.18388/abp.2020_6889
Source: Acta Biochim Pol - September 17, 2023 Category: Biochemistry Authors: Ma łgorzata Kaczkan Sylwia Czaja-Stolc Ma łgorzata Sikorska-Wiśniewska Micha ł Chmielewski Alicja D ębska-Ślizień Sylwia Ma łgorzewicz Source Type: research
Osteosarcoma's genetic landscape painted by genes' mutations
CONCLUSIONS: Their role in cancerogenesis was confirmed by the analysis of available articles published previously. The results of the study indicate that examination of selected genes' mutations might help to identify patients' predisposition to OS development, as well as monitor the disease progression, and establish prognosis. However, to fully understand the pathogenesis of OS further studies are required.PMID:37717265 | DOI:10.18388/abp.2020_6869
Source: Acta Biochim Pol - September 17, 2023 Category: Biochemistry Authors: Wiktoria Urban Dagmara Krzysta ńska Micha ł Piekarz Jerzy Nazar Anna Jankowska Source Type: research
TORC1 mediated regulation of mitochondrial integrity and calcium ion homeostasis by Wat1/mLst8 in S. pombe
Int J Biol Macromol. 2023 Sep 15:126907. doi: 10.1016/j.ijbiomac.2023.126907. Online ahead of print.ABSTRACTThe mTOR complexes play a fundamental role in mitochondrial biogenesis and cellular homeostasis. Wat1, an ortholog of mammalian Lst8 is an important component of TOR complex and is essential for the regulation of downstream signaling. Earlier we reported the role of Wat1 in oxidative stress response. Here, we have shown that the abrogation of wat1 causes respiratory defects and mitochondrial depolarization that leads to a decrease in ATP production. The confocal and electron microscopy in wat1Δ cells revealed the fr...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Simmi Anjum Swati Srivastava Lalita Panigrahi Uzair Ahmad Ansari Arun Kumar Trivedi Shakil Ahmed Source Type: research
Bioderived cellulose fibre-guar gum grafted poly (N, N'-dimethylacrylamide) polymer network for controlled release of metformin hydrochloride
Int J Biol Macromol. 2023 Sep 15:126882. doi: 10.1016/j.ijbiomac.2023.126882. Online ahead of print.ABSTRACTAn interpenetrating polymer network (IPN) of areca cellulose and guar gum grafted with poly (N, N'-dimethylacrylamide) was made by microwave irradiation technique. N, N-methylenebisacrylamide (MBA) was used as the crosslinking agent. The network polymer was characterised using Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric Analysis (TGA), Powder X-ray Diffraction (XRD) and Field Emission Scanning Electron Microscopy (FESEM). The chemical interaction between the drug and the polymer was studied usin...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Smitha Rai Ruchira Raychaudhuri Ritu Kudarha Srinivas Mutalik B Vishalakshi K M Usha Source Type: research
Superwettable cellulose acetate-based nanofiber membrane with spider-web structure for highly efficient oily water purification
This study provides a novel strategy for the construction of the high-performance oil/water separation membrane.PMID:37717870 | DOI:10.1016/j.ijbiomac.2023.126865
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Doudou Ning Zhaoqing Lu Cuiyu Tian Ning Yan Fan Xie Nan Li Li Hua Source Type: research
Curcumin-capped gold nanorods as optical sensing platform for sequence specific detection of DNA based on their self-assembly
Int J Biol Macromol. 2023 Sep 15:126829. doi: 10.1016/j.ijbiomac.2023.126829. Online ahead of print.ABSTRACTWe are reporting curcumin-induced gold nanorods as an optical sensing platform for the detection of sequence-specific DNA target through their self-assembly. The combined effect of eco-friendly reducing agent (i.e., curcumin) and silver nitrate in a basic medium (i.e., pH 10) has been attributed for the formation of small gold nanorods (AuNRs) having approximate length and diameter i.e., 19.7 ± 0.8 nm and 6.0 ± 0.5 nm, respectively, and lower longitudinal surface plasmon resonance (SPR) enable to detect and analyse...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Sanyukta Mayuri Niki Sweta Jha Shailendra Kumar Jha Source Type: research
Distribution-according-to-work: Enhancing solar vapor generation of photothermal sponge by using cellulose-based water storage platform
This report proposes a novel approach to designing an ISVG device that incorporates effective water management strategy for achieving high-efficiency water purification in real-world scenarios.PMID:37717868 | DOI:10.1016/j.ijbiomac.2023.126830
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Changyuan Song Yin Jin Source Type: research
Carboxymethyl chitosan-TK resistant starch complex ameliorates type 2 diabetes by regulating the gut microbiota
Int J Biol Macromol. 2023 Sep 15:126930. doi: 10.1016/j.ijbiomac.2023.126930. Online ahead of print.ABSTRACTCarboxymethyl chitosan and resistant starch exhibit good performance in diabetes regulation. We prepared carboxymethyl chitosan - resistant starch complex. Test the properties of composite resistant starch by using X-ray diffraction, water contact angle, infrared spectroscopy, and scanning electron microscopy, interactions with intestinal microbiota and mouse experiments were also conducted. The results indicated that the composite resistant starch had a good effect on promoting the proliferation of probiotics on Bif...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Xin Pan Pei Liu Ye-Jun Zhang Hao-Kuang Zhang Hao Wei Jing-Yi Jiang None Hui-Yan Er-Xin Shang Wei-Wen Li Yiwei Wang Jin-Ao Duan Source Type: research
Baicalin functionalized PEI-heparin carbon dots as cancer theranostic agent
Int J Biol Macromol. 2023 Sep 15:126846. doi: 10.1016/j.ijbiomac.2023.126846. Online ahead of print.ABSTRACTThe worldwide prevalence of cancer and its significantly rising risks with age have garnered the attention of nanotechnology for prompt detection and effective therapy with minimal or no adverse effects. In the current study, heparin (HP) polymer derived heteroatom (N, S-) co-doped CDs were synthesized using hydrothermal synthesis method to efficiently deliver natural anticancer compound baicalin (BA). Heparin carbon dots (HCDs) were passivated with polyethylenimine (PEI) to improve its fluorescence quantum yield. Th...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Mukesh Kumar Meher B S Unnikrishnan Deepak Kumar Tripathi Gopinath Packirisamy Krishna Mohan Poluri Source Type: research
Preparation and characterization of polyvinyl alcohol/sodium lignosulfonate/black rice anthocyanin extract agricultural film for monitoring soil pH
This study focuses on the formulation of polyvinyl alcohol (PVA)-based films with pH-sensitive properties and ultraviolet (UV) resistance by incorporating sodium lignosulfonate (LS) and varying concentrations of black rice anthocyanin extract (BRE) into PVA matrix. The films were characterized through Fourier transform-infrared spectroscopy (FT-IR), X-ray diffraction (XRD), tensile test, water vapor permeability (WVP), and ultraviolet-visible (UV-vis) spectroscopy. The results indicated that BRE and LS effectively formed strong hydrogen bonds with PVA, leading to reduced film crystallinity, improved mechanical properties, ...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Lili Ren Siqi Yang Nan Wu Jian Xu Source Type: research
Therapeutic mechanism exploration of polysaccharides from Dendrobium officinale on unilateral ureteral obstruction operation-induced renal fibrosis based on improving oxidative stress injury mediated by AhR/NOX4 pathway
Int J Biol Macromol. 2023 Sep 15:126920. doi: 10.1016/j.ijbiomac.2023.126920. Online ahead of print.ABSTRACTDendrobium officinale polysaccharides (DOP) has been reported to possess remarkable effects on improving renal function, oxidative stress damage and fibrotic diseases. However, the role and mechanism of DOP in preventing and treating renal fibrosis remain unclear. The purpose of this paper was to explore the therapeutic effects and underlying mechanisms of DOP on renal fibrosis. Firstly, renal fibrosis model was induced by unilateral ureteral obstruction operation (UUO) in male BALB/c mice. Subsequently, the anti-ren...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Yingying Shi Li Zhou Guangzhen Zheng Yi Jing Xu Zhang Jun Yuan Qianghua Zhang Hailun Li Song Huang Tian Xie Qingping Xiong Source Type: research
Rational design for thermostability improvement of a novel PL-31 family alginate lyase from Paenibacillus sp. YN15
This study provided a promising ALyase mutant for AOS industrial production.PMID:37717863 | DOI:10.1016/j.ijbiomac.2023.126919
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Wenli Zhang Hu Ren Xinxiu Wang Quanyu Dai Xiaoyong Liu Dawei Ni Yingying Zhu Wei Xu Wanmeng Mu Source Type: research
Green synthesis of multifunctional zinc oxide nanoparticles from cordia myxa gum; and their catalytic reduction of nitrophenol, anticancer and antimicrobial activity
This study uses CMX gum as a bioreduction to produce multifunctional, environmentally friendly zinc-oxide nanocomposites (ZnO NPs). The process involves a low reaction time and temperature and utilizes CMX as a reducing and stabilizing agent. The structural, morphological, and optical properties of the CMX-ZnO nanocomposite were characterized. The biosynthetic CMX-ZnO NPs exhibited robust catalytic activity and recycling capacity for rapidly oxidizing hazardous p-NPs. The complete reduction of 4-NP to CMX-ZnO NPs in excess NaBH4 was achieved within 15 min, with recyclability and pseudo-first-order kinetics with a rate cons...
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Kasula Nagaraja O H Tae Hwan Source Type: research
