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Therapy: Radiation Therapy

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Total 11968 results found since Jan 2013.

Radiation therapy in the thoracic region: Radio-induced cardiovascular disease, cardiac delineation and sparing, cardiac dose constraints, and cardiac implantable electronic devices
This article will summarize available cardiac dose constraints in various clinical settings and the types of radio-induced cardiovascular diseases encountered as well as delineation of cardiac subheadings and management of cardiac devices. Although still not completely deciphered, heart dose constraints remain intensively investigated and the mean dose to the heart is no longer the only dosimetric parameter to consider since the left anterior descending artery as well as the left ventricle should also be part of dosimetry constraints.PMID:37648559 | DOI:10.1016/j.canrad.2023.06.027
Source: Cancer Radiotherapie - August 30, 2023 Category: Cancer & Oncology Authors: C Petit A Escande T Sarrade L Vaugier Y Kirova A Tallet Source Type: research

Selecting the optimal radiation modality in prostate cancer
Clin Adv Hematol Oncol. 2023 Sep;21(9):494-501.ABSTRACTThere are numerous radiation modalities for the definitive treatment of localized prostate cancer. Classic clinical trials have established the basic tenets of treatment approaches, and emerging data have generated new potential avenues of treatment that optimize the therapeutic ratio by increasing prostate cancer tumor control while minimizing treatment-related toxicity. In the definitive setting, the selection of the optimal radiation therapy approach depends largely on the appropriate up-front risk stratification of men with prostate cancer, with greater intensifica...
Source: Clinical Prostate Cancer - August 30, 2023 Category: Cancer & Oncology Authors: Luca F Valle Amar U Kishan Antonio Franco Ting Martin Ma John Nikitas Matthew Farrell Albert J Chang Nicholas G Nickols Michael L Steinberg Source Type: research

Definitive ablative stereotactic partial breast irradiation in early stage inoperable breast cancer
CONCLUSIONS: Our case series suggests that definitive ablative radiation therapy may serve as a safe and effective treatment option for non-operable patients with early stage breast cancer. The observed durable treatment responses and minimal toxicity support the potential of this approach. Furthermore, a longer interval between ablative radiation therapy and surgery may enhance treatment response, potentially leading to increased complete pathologic response rates.PMID:37648809 | DOI:10.1007/s00432-023-05053-x
Source: Clinical Breast Cancer - August 30, 2023 Category: Cancer & Oncology Authors: Mihailo Miljanic Chika Nwachukwu Assal Rahimi Source Type: research

Radiation therapy in the thoracic region: Radio-induced cardiovascular disease, cardiac delineation and sparing, cardiac dose constraints, and cardiac implantable electronic devices
This article will summarize available cardiac dose constraints in various clinical settings and the types of radio-induced cardiovascular diseases encountered as well as delineation of cardiac subheadings and management of cardiac devices. Although still not completely deciphered, heart dose constraints remain intensively investigated and the mean dose to the heart is no longer the only dosimetric parameter to consider since the left anterior descending artery as well as the left ventricle should also be part of dosimetry constraints.PMID:37648559 | DOI:10.1016/j.canrad.2023.06.027
Source: Cancer Radiotherapie - August 30, 2023 Category: Cancer & Oncology Authors: C Petit A Escande T Sarrade L Vaugier Y Kirova A Tallet Source Type: research

Selecting the optimal radiation modality in prostate cancer
Clin Adv Hematol Oncol. 2023 Sep;21(9):494-501.ABSTRACTThere are numerous radiation modalities for the definitive treatment of localized prostate cancer. Classic clinical trials have established the basic tenets of treatment approaches, and emerging data have generated new potential avenues of treatment that optimize the therapeutic ratio by increasing prostate cancer tumor control while minimizing treatment-related toxicity. In the definitive setting, the selection of the optimal radiation therapy approach depends largely on the appropriate up-front risk stratification of men with prostate cancer, with greater intensifica...
Source: Adv Data - August 30, 2023 Category: Epidemiology Authors: Luca F Valle Amar U Kishan Antonio Franco Ting Martin Ma John Nikitas Matthew Farrell Albert J Chang Nicholas G Nickols Michael L Steinberg Source Type: research

Radiation therapy in the thoracic region: Radio-induced cardiovascular disease, cardiac delineation and sparing, cardiac dose constraints, and cardiac implantable electronic devices
This article will summarize available cardiac dose constraints in various clinical settings and the types of radio-induced cardiovascular diseases encountered as well as delineation of cardiac subheadings and management of cardiac devices. Although still not completely deciphered, heart dose constraints remain intensively investigated and the mean dose to the heart is no longer the only dosimetric parameter to consider since the left anterior descending artery as well as the left ventricle should also be part of dosimetry constraints.PMID:37648559 | DOI:10.1016/j.canrad.2023.06.027
Source: Cancer Radiotherapie - August 30, 2023 Category: Cancer & Oncology Authors: C Petit A Escande T Sarrade L Vaugier Y Kirova A Tallet Source Type: research

Developing a Prediction Model for Radiation Pneumonitis in Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy Combined With Clinical, Dosimetric Factors, and Laboratory Biomarkers
CONCLUSION: Age, lung volume, fractional dose, V10, and Hb levels were demonstrated to be significant factors associated with grade ≥2 RP for lung cancer patients after SBRT. A novel model combining clinical, dosimetric factors, and laboratory biomarkers improved predictive performance compared with the clinical and dosimetric model alone.PMID:37648569 | DOI:10.1016/j.cllc.2023.08.007
Source: Clinical Lung Cancer - August 30, 2023 Category: Cancer & Oncology Authors: Bao-Tian Huang Pei-Xian Lin Ying Wang Li-Mei Luo Source Type: research

Definitive ablative stereotactic partial breast irradiation in early stage inoperable breast cancer
CONCLUSIONS: Our case series suggests that definitive ablative radiation therapy may serve as a safe and effective treatment option for non-operable patients with early stage breast cancer. The observed durable treatment responses and minimal toxicity support the potential of this approach. Furthermore, a longer interval between ablative radiation therapy and surgery may enhance treatment response, potentially leading to increased complete pathologic response rates.PMID:37648809 | DOI:10.1007/s00432-023-05053-x
Source: Clinical Genitourinary Cancer - August 30, 2023 Category: Cancer & Oncology Authors: Mihailo Miljanic Chika Nwachukwu Assal Rahimi Source Type: research

Selecting the optimal radiation modality in prostate cancer
Clin Adv Hematol Oncol. 2023 Sep;21(9):494-501.ABSTRACTThere are numerous radiation modalities for the definitive treatment of localized prostate cancer. Classic clinical trials have established the basic tenets of treatment approaches, and emerging data have generated new potential avenues of treatment that optimize the therapeutic ratio by increasing prostate cancer tumor control while minimizing treatment-related toxicity. In the definitive setting, the selection of the optimal radiation therapy approach depends largely on the appropriate up-front risk stratification of men with prostate cancer, with greater intensifica...
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Luca F Valle Amar U Kishan Antonio Franco Ting Martin Ma John Nikitas Matthew Farrell Albert J Chang Nicholas G Nickols Michael L Steinberg Source Type: research

Evaluation and correlation of patient movement during online adaptive radiotherapy with CBCT and a surface imaging system
CONCLUSION: Surface imaging should be used to monitor and quantify patient movement during adaptive radiotherapy.PMID:37643456 | DOI:10.1002/acm2.14133
Source: Journal of Applied Clinical Medical Physics - August 29, 2023 Category: Physics Authors: Dennis N Stanley Elizabeth Covington Joseph Harms Joel Pogue Carlos E Cardenas Richard A Popple Source Type: research

Whole-pelvic irradiation with boost to involved nodes and prostate in node-positive prostate cancer-long-term data from the prospective PLATIN-2  trial
CONCLUSION: Definitive radiation to the lymphatic drainage with SIB to the involved nodes and prostate is a safe and effective treatment approach for patients with treatment-naïve, node-positive prostate cancer with excellent infield tumor control rates and tolerable toxicity. Location rather than number of involved nodes is a major risk factor for progression.PMID:37640867 | DOI:10.1007/s00066-023-02129-y
Source: Methods of Information in Medicine - August 28, 2023 Category: Information Technology Authors: C A Fink D Wegener L D Sauer C J äkel D Zips J Debus K Herfarth S A Koerber Source Type: research

Surgical Management of Meningiomas Involving the Torcula, Transverse Sinus, and Jugular Bulb: A Technical Note and Review of the Literature
J Neurol Surg Rep. 2023 Aug 25;84(3):e92-e102. doi: 10.1055/s-0043-1772201. eCollection 2023 Jul.ABSTRACTMeningiomas that invade the confluens sinuum are rare and require extensive preoperative planning. Here, we describe the surgical and radio-oncological management of an aggressive large occipital meningioma invading the superior sagittal sinus, torcula, right and left transverse sinus down to the level of the jugular bulb in a 21-year-old female patient. Details of the surgical approach are presented to highlight the planned staged resection of this tumor at the level of the torcula to initially debulk the lesion while ...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Robert G Power Fred C Lam Anthony C Whitton Sunjay Sharma Ekkehard M Kasper Source Type: research

The 5-Year Disease-Free Survival of Third Generation Aromatase Inhibitor for Postmenopausal Women with HR-Positive HER2-Negative Non-Metastatic Breast Cancer
Conclusion: 5-year letrozole administration could be proposed as first-line therapy for postmenopausal women with HR-positive HER2-negative BC. A considerable subject and long-term follow-up are needed for validation.PMID:37638281 | PMC:PMC10448920 | DOI:10.18502/ijhoscr.v17i1.11713
Source: Cell Research - August 28, 2023 Category: Cytology Authors: Ria Etikasari Tri Murti Andayani Dwi Endarti Kartika Widayati Taroeno-Hariadi Source Type: research