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Therapy: Radiation Therapy
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Total 11968 results found since Jan 2013.
ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
Curr Issues Mol Biol. 2023 Jul 27;45(8):6262-6271. doi: 10.3390/cimb45080394.ABSTRACTRadiation therapy is commonly used to treat head and neck squamous cell carcinoma (HNSCC); however, recurrence results from the development of radioresistant cancer cells. Therefore, it is necessary to identify the underlying mechanisms of radioresistance in HNSCC. Previously, we showed that the inhibition of karyopherin-β1 (KPNB1), a factor in the nuclear transport system, enhances radiation-induced cytotoxicity, specifically in HNSCC cells, and decreases the localization of SCC-specific transcription factor ΔNp63. This suggests that Δ...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Kota Sato Hironori Yoshino Yoshiaki Sato Manabu Nakano Eichi Tsuruga Source Type: research
Efficacy of sesame oil versus placebo in the management of acute radiation-induced dermatitis in breast cancer patients: A double-blind randomized clinical trial
CONCLUSION: Based on the findings, sesame oil, as a cheap and available herbal treatment, may be utilized in treating acute dermatitis caused by radiotherapy. However, an investigation with a larger sample size in several centers should be conducted to examine sesame oil effects in treating acute radio dermatitis more comprehensively.PMID:37620987 | DOI:10.1111/ajco.13999
Source: Clinical Breast Cancer - August 24, 2023 Category: Cancer & Oncology Authors: Dariush Moslemi Sepehr Ramezany Ali Akbar Moghadamnia Saba Ebrahimian Source Type: research
A Case of Locally Advanced, Unresectable Pancreatic Cancer with Superior Mesenteric Artery Invasion Treated with FOLFIRINOX plus Radiation Therapy, followed by Conversion Surgery
We report a case of a woman in her 70s who underwent conversion surgery after FOLFIRINOX, followed by radiation therapy for initially locally advanced unresectable pancreatic cancer. She visited her local doctor with a chief complaint of upper abdominal pain. Contrast-enhanced CT scan of the abdomen revealed an irregular mass invading the superior mesenteric artery, and the first and second jejunal arteries(>180°)in the pancreatic uncinate region. Based on imaging, she was diagnosed as UR-LA(sm), cT4N0M0, cStage Ⅲ pancreatic cancer, and underwent 5 courses of modified FOLFIRINOX. Radiation therapy of 50.4 Gy was adde...
Source: Cancer Control - August 23, 2023 Category: Cancer & Oncology Authors: Hiroki Tani Hiroyuki Kato Yukio Asano Masahiro Ito Satoshi Arakawa Masahiro Shimura Daisuke Koike Takayuki Ochi Kenshiro Kamio Toki Kawai Hironobu Yasuoka Takahiko Higashiguchi Yoshiki Kunimura Kazuma Horiguchi Hidetoshi Nagata Yuka Kondo Yutaro Kato Tsun Source Type: research
In vivo dosimetry in cancer patients undergoing intraoperative radiation therapy
Phys Med Biol. 2023 Aug 22. doi: 10.1088/1361-6560/acf2e4. Online ahead of print.ABSTRACTIn vivo dosimetry (IVD) is an important tool in external beam radiotherapy to detect major errors by assessing differences between expected and delivered dose and to record the received dose by individual patients. Also, in intraoperative radiation therapy (IORT), IVD is highly relevant to register the delivered dose. This is especially relevant in low-risk breast cancer patients since a high dose of IORT is delivered in a single fraction. In contrast to external beam radiotherapy, online treatment planning based on intraoperative imag...
Source: Physics in Medicine and Biology - August 22, 2023 Category: Physics Authors: Anna L Petoukhova Roland Snijder Thomas Vissers Heleen Ceha Henk Struikmans Source Type: research
