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Vaccination: Veterinary Vaccinations

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Total 7225 results found since Jan 2013.

3Rs implementation in veterinary vaccine batch-release testing: Current state-of-the-art and future opportunities. A webinar and workshop report
Biologicals. 2023 Jul 27;83:101695. doi: 10.1016/j.biologicals.2023.101695. Online ahead of print.ABSTRACTRegulatory authorities require veterinary batch-release testing to confirm vaccine potency and safety, but these tests have traditionally relied on large numbers of laboratory animals. Advances in vaccine research and development offer increasing opportunities to replace in vivo testing, and some stakeholders have made significant progress in incorporating 3Rs elements in quality control strategies. A three-part event series entitled "3Rs Implementation in Veterinary Vaccine Batch-Release Testing: Current state-of-the-...
Source: Biologicals : Journal of the International Association of Biological Standardization - July 29, 2023 Category: Biotechnology Authors: Laura Viviani Elisabeth Balks Sonja Beken Anna-Maria Brady Rick Clayton Florence Cliquet Liys Desmayanti Silvia Fragoeiro Terrie Jo Hamtak David John Carmen Jungba ëck M Kalaivani Imke Kross Catherine Lang Ni Made Ria Isriyanthi Laurent Mallet Catherine Source Type: research

Cancers, Vol. 15, Pages 3836: Cancer Bioenergetics and Tumor Microenvironments & mdash;Enhancing Chemotherapeutics and Targeting Resistant Niches through Nanosystems
Cancers, Vol. 15, Pages 3836: Cancer Bioenergetics and Tumor Microenvironments—Enhancing Chemotherapeutics and Targeting Resistant Niches through Nanosystems Cancers doi: 10.3390/cancers15153836 Authors: Aisha Farhana Abdullah Alsrhani Yusuf Saleem Khan Zafar Rasheed Cancer is an impending bottleneck in the advanced scientific workflow to achieve diagnostic, prognostic, and therapeutic success. Most cancers are refractory to conventional diagnostic and chemotherapeutics due to their limited targetability, specificity, solubility, and side effects. The inherent ability of each cancer to evolve throug...
Source: Cancers - July 28, 2023 Category: Cancer & Oncology Authors: Aisha Farhana Abdullah Alsrhani Yusuf Saleem Khan Zafar Rasheed Tags: Review Source Type: research

Scientists reprogram blood cells with fat balls that target bone marrow
Some people with sickle cell disease are now healthy thanks to an experimental treatment: Researchers edit the DNA of their defective blood stem cells in a lab dish, then infuse the cells back into the body. This “ex vivo” procedure is costly and complex, however, putting it out of reach for many patients in poor countries. Now, scientists have shown they can reprogram blood cells directly inside the body by targeting genetically loaded balls of fat to the bone marrow. The advance, described today in Science , only works in mice so far and hasn’t yet cured a disease in the animals. But if it translat...
Source: Science of Aging Knowledge Environment - July 27, 2023 Category: Geriatrics Source Type: research

An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis
Appl Biochem Biotechnol. 2023 Jul 27. doi: 10.1007/s12010-023-04658-9. Online ahead of print.ABSTRACTMycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis and develops resistance to many of the existing drugs. The sole licensed TB vaccine, BCG, is unable to provide a comprehensive defense. So, it is crucial to maintain the immunological response to eliminate tuberculosis. Our previous in silico study reported five uncharacterized proteins as potential vaccine antigens. In this article, we considered the uncharacterized Mtb H37Rv regions of difference (RD-2) Rv1987 protein as a promising vaccine candidat...
Source: Applied Biochemistry and Biotechnology - July 27, 2023 Category: Biochemistry Authors: Aregitu Mekuriaw Arega Ajit Kumar Dhal Kali Prasad Pattanaik Sasmita Nayak Rajani Kanta Mahapatra Source Type: research

Bioinformatics-based design of a fusion vaccine with CTLA-4 variable region to combat Brucella
This study showed that the designed vaccine containing CTLA-4 had high potency against Brucella, which could provide a reference for the future development of efficient brucellosis vaccines.PMID:37493775 | PMC:PMC10361638 | DOI:10.1590/1414-431X2023e12938
Source: Braz J Med Biol Res - July 26, 2023 Category: Research Authors: W H Guo Y J Zhu G Haimiti X R Xie C Niu M Li J Shi Z W Yin M K Yu J B Ding F B Zhang Source Type: research

Epidemiology-driven approaches to surveillance in HPAI-vaccinated poultry flocks aiming to demonstrate freedom from circulating HPAIV
Biologicals. 2023 Jul 24;83:101694. doi: 10.1016/j.biologicals.2023.101694. Online ahead of print.ABSTRACTIncursion pressure of high pathogenicity avian influenza viruses (HPAIV) by secondary spread among poultry holdings and/or from infected migratory wild bird populations increases worldwide. Vaccination as an additional layer of protection of poultry holdings using appropriately matched vaccines aims at reducing clinical sequelae of HPAIV infection, disrupting HPAIV transmission, curtailing economic losses and animal welfare problems and cutting exposure risks of zoonotic HPAIV at the avian-human interface. Products der...
Source: Biologicals : Journal of the International Association of Biological Standardization - July 26, 2023 Category: Biotechnology Authors: Timm Harder Sjaak de Wit Jose L Gonzales Jeremy H P Ho Paolo Mulatti Teguh Y Prajitno Arjan Stegeman Source Type: research