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Total 1275 results found since Jan 2013.
Controversies in neuroimmunology: multiple sclerosis, vaccination, SARS-CoV-2 and other dilemas
This article presents 15 controversies and a discussion about them, which are built with the most up-to-date evidence available. The topics included in this review are: steroid decline in relapses of multiple sclerosis; therapeutic recommendations in MS in light of the SARS-CoV-2 pandemic; evidence of vaccination in multiple sclerosis and other demyelinating diseases; overview current situation of isolated clinical and radiological syndrome; therapeutic failure in multiple sclerosis, as well as criteria for suspension of disease-modifying therapies; evidence of the management of mild relapses in multiple sclerosis; recomme...
Source: Biomedica : Revista del Instituto Nacional de Salud - November 2, 2022 Category: International Medicine & Public Health Authors: Sa úl Reyes-Niño Jaime Eduardo Rodr íguez-Orozco Habib Georges Moutran-Barroso Hellen Kreinter-Rosembaun Mariana Gaviria-Carrillo Vanessa Salej-Dur án Juli án Mancera-Charry Ana Claudia Villegas David Cuellar-Giraldo Juan Sebasti án Torres-Sandoval Source Type: research
Level of CSF CXCL10 is highly elevated and decreased after steroid therapy in patients with autoimmune glial fibrillary acidic protein astrocytopathy
ConclusionCSF CXCL10 levels were particularly high in GFAP-A, and changes in levels after treatment correlated with clinical improvements, suggesting CXCL10 involvement in GFAP-A pathogenesis.
Source: Clinical and Experimental Neuroimmunology - October 26, 2022 Category: Neurology Authors: Takayuki Kikuchi,
Naoki Takao,
Tomoo Sato,
Isahaya Kenji,
Sakae Hino,
Kaburagi Mayumi,
Tachikawa Keiji,
Ko Riyoko,
Soichiro Shibata,
Kei Kaburagi,
Naoki Iijima,
Heisuke Mizukami,
Kenzo Sakurai,
Junji Yamauchi,
Akio Kimura,
Takayoshi Shimoha Tags: ORIGINAL ARTICLE Source Type: research
Epidemiology, clinical presentation, treatment, and outcome of neurosarcoidosis: A mono-centric retrospective study and literature review
ConclusionThe results of our cohort and literature review confirm that neurosarcoidosis occurred most frequently in the context of systemic sarcoidosis. Methotrexate is the most frequent second-line therapy. The effectiveness of therapy with TNF-α antagonists is well-demonstrated and associated with a better outcome. Their earlier use during the disease course among aggressive and/or refractory neurosarcoidosis should be considered.
Source: Frontiers in Neurology - October 25, 2022 Category: Neurology Source Type: research
Neurosarcoidosis: A call to arms
Neurosarcoidosis arises when a patient with systemic sarcoidosis either develops neurological involvement, or when the nervous system is the first or only organ manifestation of sarcoidosis. The protean ways in which neurosarcoidosis can present in the nervous system means the astute clinician needs to be alert to the possibility and have a systematic approach to diagnosis and treatment. Failure to consider neurosarcoidosis as a diagnostic possibility, or the limitations related to obtaining a tissue diagnosis, can result in serious morbidity (Bradshaw et al., 2021).
Source: Journal of Neuroimmunology - October 18, 2022 Category: Allergy & Immunology Authors: Todd A. Hardy, David B. Clifford Source Type: research
Neurosarcoidosis during the treatment of primary Sj ögren's syndrome: is it a paradoxical effect of rituximab?
Clin Exp Rheumatol. 2022 Oct 12. doi: 10.55563/clinexprheumatol/2yhllj. Online ahead of print.NO ABSTRACTPMID:36226627 | DOI:10.55563/clinexprheumatol/2yhllj
Source: Clinical and Experimental Rheumatology - October 13, 2022 Category: Rheumatology Authors: Rafael Alves Cordeiro Jobson L de Oliveira Suely F Ferraciolli Lissiane K N Guedes Sandra G Pasoto Source Type: research
