Renal sarcoidosis presenting with chronic kidney disease and hypercalcemia
We describe a 72-year-old male who presented with chronic kidney disease and elevated serum calcium and angiotensin-converting enzyme. Renal biopsy pathology showed chronic granulomatous interstitial nephritis. Renal function was significantly improved after glucocorticoid therapy. This case emphasizes that chronic kidney disease and hypercalcemia can be clues for renal sarcoidosis. Early renal biopsy and projective treatment is beneficial for renal outcome.PMID:37548467 | DOI:10.5414/CN111115
Source: Clinical Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Yuanyuan Wang Feng Du Hua Zhou Source Type: research

Sarcoidosis presenting as encephalitis: case report and review of the literature
Source: Neurological Sciences - August 7, 2023 Category: Neurology Source Type: research

Hybrid PET/MRI imaging in non-ischemic cardiovascular disease
ConclusionThe current review confirms the utility of PET/MRI in providing a comprehensive assessment of non-ischemic cardiovascular diseases.
Source: Clinical and Translational Imaging - August 5, 2023 Category: Radiology Source Type: research

Deep convolutional neural network for differentiating between sarcoidosis and lymphoma based on 18FFDG maximum-intensity projection images
ConclusionsCNN models based on differences in FDG accumulation sites archive high performance in differentiating between sarcoidosis and ML.Clinical relevance statementWe developed a CNN model using MIP images of [18F]FDG PET/CT to distinguish between sarcoidosis and malignant lymphoma. It achieved high performance and could be useful in diagnosing diseases with involvement across organs and lymph nodes.Key Points• There are differences in FDG distribution when comparing whole-body [18F]FDG PET/CT findings in patients with sarcoidosis and malignant lymphoma before treatment.• Convolutional neural networks, a type of de...
Source: European Radiology - August 3, 2023 Category: Radiology Source Type: research

Osseous Metastasis: An Unusual Sarcoidosis Masquerade
A man in his 50s presented to the clinic with the chief complaint of low back pain. He had served in the US Army with burn pit exposure in the Middle East. Lumbar magnetic resonance imaging revealed irregular, rounded lesions in multiple vertebral bodies (Supplemental Figure  1, available online at http://www.mayoclinicproceedings.org). Follow-up positron emission tomography revealed 18F-fluorodeoxyglucose–avid lesions throughout the entire axial skeleton, right femur, and right humerus (Figure 1 and Supplemental Figure 2).
Source: Mayo Clinic Proceedings - August 1, 2023 Category: Internal Medicine Authors: Johnny F. Jaber, Robert W. Allan, Suzanne Mastin, Grant Lowther Tags: Medical image Source Type: research

Epidemiology of Sarcoidosis
Sarcoidosis is a systemic, granulomatous disease with variable presentation earning it the term “the great mimicker.” The current epidemiology confirms that the disease occurs worldwide, affecting both sexes, and all races, ethnicities, and ages. To date, no causal exposure or agent has been identified. The organ systems most frequently affected by sarcoidosis are also those with greatest exposure to the natural world suggesting environmental and lifestyle contributions to the disease. These include particulate matter, microorganisms, nicotine, and obesity. In this article, we review the epidemiology of sarcoidosis and...
Source: Clinics in Chest Medicine - August 1, 2023 Category: Respiratory Medicine Authors: Yvette C. Cozier, Elizabeth V. Arkema Source Type: research

Sarcoidosis mimicking nodal manifestations of marginal zone lymphoma
Source: European Journal of Nuclear Medicine and Molecular Imaging - July 29, 2023 Category: Nuclear Medicine Source Type: research

Expiratory CT scan: When to do it and how to interpret it
Radiologia (Engl Ed). 2023 Jul-Aug;65(4):352-361. doi: 10.1016/j.rxeng.2023.01.008. Epub 2023 Jul 12.ABSTRACTExpiratory CT scan is a complementary technique of inspiratory CT that provide valuable physiological information and may be more sensitive to detect air trapping than pul-monary function tests. It is useful in many obstructive airway diseases, including obliterative bronchiolitis, asthma, Swyer-James syndrome, tracheomalacia, hypersensitivity pneumonitis and sarcoidosis. In obliterative bronchiolitis, expiratory CT scan may be the only imaging technique that shows abnormalities in the early phase of disease. In ord...
Source: Radiologia - July 29, 2023 Category: Radiology Authors: A Mart ínez de Alegría Alonso A Berm údez Naveira D Uceda Navarro M Dom ínguez Robla Source Type: research

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