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Cancer: Pineoblastoma

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Total 36 results found since Jan 2013.

Large pineal parenchymal tumor of intermediate differentiation causing compression with resultant obstructive hydrocephalus: a case report
CONCLUSION: One should carefully investigate a headache as the early symptom of many illnesses and rule out any other potential causes. This would therefore enable us to create a management structure for such a very unusual malignancy.PMID:36923739 | PMC:PMC10010788 | DOI:10.1097/MS9.0000000000000147
Source: Annals of Medicine - March 16, 2023 Category: Internal Medicine Authors: Oadi N Shrateh Afnan W M Jobran Haneen Owienah Thaer Sweileh Mohand Abulihya Nadeem Shahin Yazan Atawnah Abdalwahab Kharousha Hadi Dababseh Sami Hussein Source Type: research

Simultaneous single-trajectory endoscopic biopsy and third ventriculostomy in pediatric pineal region tumors
AbstractPineal region tumors have different pathological tumors and their optimal management remains controversial. Advancements in neuroendoscopy have led to the ability to simultaneously treat the hydrocephalus and obtain a tissue diagnosis. A retrospective review of 34 patients with pineal region tumors in Beijing Tiantan hospital from the year 2016 to 2018 was undertaken. A single bur hole for both procedures was used successfully in all patients. Once pathologic diagnosis is made, the subsequent management of different tumors is dependent on response to therapy, the tumor markers and original pathology. Follow-up peri...
Source: Acta Neurologica Belgica - June 5, 2020 Category: Neurology Source Type: research

Benign and Malignant Tumors of the Pineal Region
Adv Exp Med Biol. 2023;1405:153-173. doi: 10.1007/978-3-031-23705-8_6.ABSTRACTPineal region tumors fall into five broad categories: benign pineal region tumors, glial tumors, papillary tumors, pineal parenchymal tumors, and germ cell tumors. Genetic and transcriptional studies have identified key chromosomal alterations in germinomas (RUNDC3A, ASAH1, LPL) and in pineocytomas/pineoblastomas (DROSHA/DICER1, RB1). Pineal region tumors generally present with symptoms of hydrocephalus including nausea, vomiting, papilledema, and the classical Parinaud's triad of upgaze paralysis, convergence-retraction nystagmus, and light-near...
Source: Advances in Experimental Medicine and Biology - July 15, 2023 Category: Research Authors: Pavan S Upadhyayula Justin A Neira Michael L Miller Jeffrey N Bruce Source Type: research

Combined rigid and flexible endoscopy for tumors in the posterior third ventricle.
CONCLUSIONS The authors recommend using a combined rigid-flexible endoscope for endoscopic third ventriculostomy and biopsy to approach posterior third ventricular tumors (behind the massa intermedia). This technique overcomes the limitations of using a rigid endoscope by reaching 2 distant regions. PMID: 25816082 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 27, 2015 Category: Neurosurgery Authors: Roth J, Constantini S Tags: J Neurosurg Source Type: research

The supracerebellar infratentorial approach in pineal region tumors: Technique and outcome in an underprivileged setting
Conclusion In Alexandria university, the supracerebellar infratentorial approach is considered a safe approach with minimal morbidity and no surgery related mortality.
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Cn-12 * pineal parenchymal tumour of intermediate differentiation: case series from a single institute
CONCLUSION: Patients with PPTID in this case series survived medium term and four remain on follow up. A prospective multi institutional study is recommended due to the potential for late adverse effects. However, because this entity is rare, the difficulties in achieving this are recognised therefore cases should be collated at centres for review.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Mahtab, N., Ramamurthy, S., Willis, N., Lewis, J., Lethbridge, E. Tags: COMPLICATIONS OF THERAPY AND NEUROTOXICITY Source Type: research

Clinical, Pathological, and Surgical Outcomes for Adult Pineoblastomas
Conclusions Although this series is small, the data suggest that pineoblastomas in adults have a less aggressive clinical course than in children.
Source: World Neurosurgery - August 17, 2015 Category: Neurosurgery Source Type: research

Upfront Stereotactic Radiosurgery for Pineal Parenchymal Tumors in Adults.
CONCLUSION: SRS is effective and safe for PPTs in adults and can be considered as a useful alternative to surgical resection at upfront setting. PMID: 26587186 [PubMed - as supplied by publisher]
Source: Journal of Korean Neurosurgical Society - November 21, 2015 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Clinical Reasoning: Left hemiparesis, ataxia, and optic neuritis in a child previously treated for pineoblastoma
A 13-year-old girl presented acutely with an episode of headache and signs of elevated intracranial pressure from a pineal gland tumor causing obstructive hydrocephalus. After an endoscopic third ventriculostomy and pineal gland biopsy, she was diagnosed with pineoblastoma. She was treated with surgical resection, craniospinal radiotherapy, and subsequent chemotherapy. Brain MRIs were performed every 3 months after surgery and remained stable with no new lesions or signs of residual tumor. However, a follow-up brain MRI performed 6 months after chemotherapy showed some small white matter nonenhancing lesions in supratentor...
Source: Neurology - April 10, 2016 Category: Neurology Authors: Vila-Bedmar, S., Nourbakhsh, B., Anzalone, S., Waubant, E. Tags: MRI, Chemotherapy-tumor, Radiation therapy-tumor, Multiple sclerosis RESIDENT AND FELLOW SECTION Source Type: research

Treatment Results for Pineal Region Tumors: Role of Stereotactic Biopsy Plus Adjuvant Therapy vs. Open Resection.
CONCLUSION: The results of the study suggests that although gross total resection is the standard of care in most pineal tumors nowadays, stereotactic biopsy followed by adjuvant therapy may still be a safe and viable option. PMID: 27161457 [PubMed - in process]
Source: Turkish Neurosurgery - May 12, 2016 Category: Neurosurgery Authors: Motiei-Langroudi R, Sadeghian H, Soleimani MM, Seddighi AS, Shahzadi S Tags: Turk Neurosurg Source Type: research