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Total 315 results found since Jan 2013.

'his walking isn't right doctor': a case of hydrocephalus presenting as an abnormal gait
Conclusions This case illustrates one of the manifold ways in which hydrocephalus can present. These include changes in heart rate and respiratory rate, confusion, cranial nerve palsies, and abnormalities of motor function. When assessing a patient with a spastic gait there are a number of pathologies to be considered. It is important not to forget to consider hydrocephalus as this is a potentially chronic and progressive cause that has a significant mortality but for which there is a definitive surgical management option that can lead to a complete resolution of symptoms.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Baker, J. Tags: Immunology (including allergy), Cranial nerves, Headache (including migraine), Hydrocephalus, Multiple sclerosis, Pain (neurology), Spinal cord Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 2 Source Type: research

Finally, open loop control of intracranial pressure in hydrocephalus
In the recent paper by Farahmand et al1 a new fully implantable telemetered intracranial pressure monitoring device (Raumedic AG, Helmbrecht, Germany) is used to study changes in intracranial pressure that occur in various positions and with various valve settings. The patient population studied here included 15 adult patients with ‘communicating hydrocephalus’ who underwent ventriculoperitoneal shunting using a Strata valve (Medtronic Inc, Goleta, California, USA). With the development of adjustable valves for the treatment of hydrocephalus and effective devices to prevent severely negative intracranial pressu...
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2015 Category: Neurosurgery Authors: Rekate, H. L. Tags: Headache (including migraine), Hydrocephalus, Pain (neurology) Editorial commentaries Source Type: research

Safety and efficacy of gravitational shunt valves in patients with idiopathic normal pressure hydrocephalus: a pragmatic, randomised, open label, multicentre trial (SVASONA)
Conclusions Implanting a gravitational rather than another type of valve will avoid one additional overdrainage complication in about every third patient undergoing VP shunting for iNPH.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 8, 2013 Category: Neurosurgery Authors: Lemcke, J., Meier, U., Muller, C., Fritsch, M. J., Kehler, U., Langer, N., Kiefer, M., Eymann, R., Schuhmann, M. U., Speil, A., Weber, F., Remenez, V., Rohde, V., Ludwig, H.-C., Stengel, D. Tags: Open access, Headache (including migraine), Hydrocephalus, Infection (neurology), Pain (neurology) Neurosurgery Source Type: research

Automated detection of squint as a sensitive assay of sex-dependent calcitonin gene–related peptide and amylin-induced pain in mice
We developed an automated squint assay using both black C57BL/6J and white CD1 mice to measure the interpalpebral fissure area between the upper and lower eyelids as an objective quantification of pain. The automated software detected a squint response to the commonly used nociceptive stimulus formalin in C57BL/6J mice. After this validation, we used the automated assay to detect a dose-dependent squint response to a migraine trigger, the neuropeptide calcitonin gene–related peptide, including a response in female mice at a dose below detection by the manual grimace scale. Finally, we found that the calcitonin gene–rel...
Source: Pain - July 30, 2022 Category: Anesthesiology Tags: Research Paper Source Type: research

A 4-year-old girl with malaise, squint and restricted neck movement
Case history A 4-year-old girl presented with lethargy and anorexia, increasing in severity over the last few days. The child had been complaining of generalised joint pains and felt unable to move her neck. Also she complained of episodes of blurred vision, headaches and her mother reported a new onset squint. On further questioning, her mother said she had a circular rash on her forehead about 6 weeks previously, which had self-resolved. On examination, all observations were stable. She was irritable with restricted neck movement, neck stiffness and photosensitivity. Her pupils were equal and reactive but there was ...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Wyatt, C., Tighe, M. Tags: Eye Diseases, Immunology (including allergy), Drugs: infectious diseases, Meningitis, Headache (including migraine), Infection (neurology), Pain (neurology), Ophthalmology, Child and adolescent psychiatry (paedatrics), Eating disorders, Anorexia nervosa, Source Type: research

Hydrocephalus: historical analysis and considerations for treatment
AbstractHydrocephalus is a serious condition that affects patients of all ages, resulting from a multitude of causes. While the etiologies of hydrocephalus are numerous, many of the acute and chronic symptoms of the condition are shared. These symptoms include disorientation and pain (headaches), cognitive and developmental changes, vision and sleep disturbances, and gait abnormalities. This collective group of symptoms combined with the effectiveness of CSF diversion as a surgical intervention for many types of the condition suggest that the various etiologies may share common cellular and molecular dysfunctions. The inci...
Source: European Journal of Medical Research - September 1, 2022 Category: Research Source Type: research

Subdural fluid collection and hydrocephalus following cervical schwannoma resection: hydrocephalus resolution after spinal pseudomeningocele repair: case report.
This report emphasizes that hydrocephalus may be related to disorders of cerebrospinal fluid flow dynamics induced by cervical pseudomeningocele. In these rare cases, both the hydrocephalus and the symptoms are resolved by the simple correction of the pseudomeningocele. PMID: 27391399 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery.Spine - July 7, 2016 Category: Neurosurgery Authors: Benedetto N, Cagnazzo F, Gambacciani C, Perrini P Tags: J Neurosurg Spine Source Type: research

Hydrocephalus in Guillain barre syndrome: A case report and review of the literature
We describe a 23-year old woman with a history of bilateral limbs pain followed by dysarthria, dysphagia, severe quadriplegia 0/5, areflexia, loss of consciousness and dysautonomia. Neuroimaging studies revealed enlarged lateral ventricles; while Electromyography demonstrated demyelination and nerve injury. Lumbar puncture results showed elevated protein level 2.6 g/L; normal glucose and cell count. Diagnosis: GBS with hydrocephalus. Interventions: The patient was started on intravenous immunoglobulin for 5 consecutive days followed by endotracheal intubation and supportive therapy including osmotherapy and CSF dra...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Management of hydrocephalus in patients with leptomeningeal metastases: an ethical approach to decision-making
ConclusionsThe decision of how to manage LM-associated hydrocephalus is complex and requires close collaboration amongst the physician, patient, and/or patient ’s family/friends/community leaders. Ultimately, the decision should be rooted in the patients’ values and should aim to optimize a patient’s quality-of-life.
Source: Journal of Neuro-Oncology - October 1, 2018 Category: Cancer & Oncology Source Type: research

A Case Report of Hydrocephalus in a US Military Recruit.
We present a case of chronic non-communicating hydrocephalus (NCH) in a US military recruit. Non-communicating hydrocephalus is a pathologic obstruction of cerebrospinal fluid (CSF) resulting in enlargement of the ventricles and elevated intracranial pressure. The patient is an 18-year-old male recruit who was evaluated in the Naval Medical Center emergency room for left hip pain and incidentally was found to have profound ventriculomegaly on head imaging. The diagnosis and evaluation of hydrocephalus is greatly dependent on clinical history and supported by radiographic imaging. Based on these factors, one can determine i...
Source: Military Medicine - July 11, 2020 Category: International Medicine & Public Health Tags: Mil Med Source Type: research

P2-2-2 * two cases of total blindness and hydrocephalus caused by carcinomatous meningitis of gastric cancer
Discussion: Since the hydrocephalus accompanied by gastric cancer with meningeal carcinomatosis usually progress rapidly, prompt ventricular drainage is useful and mandatory to overcome oncology emergency such as progressive hydrocephalus with total blindness and respiratory failure.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Naganuma, A., Uehara, S., Hayashi, E., Hoshino, T., Kudo, T., Takagi, H., Ishihara, H., Ishiguro, K., Tanaka, T., Yoshida, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research

P2-2-2 * two cases of total blindness and hydrocephalus caused by carcinomatous meningitis of gastric cancer
Discussion: Since the hydrocephalus accompanied by gastric cancer with meningeal carcinomatosis usually progress rapidly, prompt ventricular drainage is useful and mandatory to overcome oncology emergency such as progressive hydrocephalus with total blindness and respiratory failure.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Naganuma, A., Uehara, S., Hayashi, E., Hoshino, T., Kudo, T., Takagi, H., Ishihara, H., Ishiguro, K., Tanaka, T., Yoshida, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research

Laparoscopic ventriculoperitoneal shunt with temporary external drainage for hydrocephalus: a comparison with conventional ventriculoperitoneal shunt.
CONCLUSION: Laparoscopic ventriculoperitoneal shunt with temporary external drainage is feasible and produces better clinical therapeutic effect for management of hydrocephalus. PMID: 23268423 [PubMed - in process]
Source: Journal of Southern Medical University - December 20, 2012 Category: Universities & Medical Training Authors: Chen JF, Liu CX, Zhu HS, Fu M, Lin FL, Liu J, Xie KL, Li P Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

Intracranial endodermal cyst presenting with nonobstructive hydrocephalus: A case report
We report the case of an elderly woman with intracranial endodermal cyst who presented with nonobstructive hydrocephalus. Patient concerns: A 78-year-old woman presented with acute deterioration of consciousness caused by acute hydrocephalus. She subsequently underwent ventriculoperitoneal shunt placement. Eighteen months after this operation, she developed numbness of extremities and gait and progressive cognitive disturbances. Diagnosis: Initially, the endodermal cyst could not be recognized, but it became clinically evident in the craniocervical junction after ventriculoperitoneal shunt placement. MRI revealed mul...
Source: Medicine - February 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research