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A proposed role for efflux transporters in the pathogenesis of hydrocephalus.
This article summarizes the existing evidence to support the role of efflux transporters in the pathogenesis of hydrocephalus. The location of p-gp along the pathways of macromolecular clearance and the broad substrate specificity of this abundant transporter to a variety of different macromolecules are reviewed. Involvement of p-gp in the transport of amyloid beta in Alzheimer disease and its relation to normal pressure hydrocephalus is reviewed. Finally, individual variability of p-gp expression might explain the variability in the development of hydrocephalus following intraventricular hemorrhage.
PMID: 25165050 [P...
Source: Croatian Medical Journal - August 28, 2014 Category: Journals (General) Authors: Krishnamurthy S, Tichenor MD, Satish AG, Lehmann DB Tags: Croat Med J Source Type: research
Large aneurysm of basilar artery tip mimicking midbrain tumor and causing unilateral obstructive hydrocephalus: a case report and technical note.
In conclusion, large basilar tip aneurysms associated with obstructive hydrocephalus are rare and best treated by a combination of endovascular obliteration and cerebrospinal fluid ventricular diversion. The possibility of such an aneurysm should always be considered on the differential diagnosis of cerebral ventricular growths.
PMID: 32724289 [PubMed - in process]
Source: Acta Clinica Croatica - July 31, 2020 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Transient obstructive hydrocephalus in patients with intracerebral hemorrhage:
report of two cases.
We report two cases of transient obstructive
hydrocephalus caused by obstruction of mesencephalic duct in patients that presented with altered
consciousness which resolved spontaneously in a few hours. In very rare cases, obstructive hydrocephalus
due to intraventricular hemorrhage may be transient and does not need neurosurgical or
invasive procedures for lowering raised intracranial pressure, which otherwise are currently preferred
treatment options.
PMID: 29046016 [PubMed - in process]
Source: Acta Clinica Croatica - October 20, 2017 Category: General Medicine Tags: Acta Clin Croat Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
Unusual clinical course of neurosarcoidosis manifested with acute hydrocephalus
We present a patient who developed acute hydrocephalus due to neurosarcoidosis, for which he had to be operated on; soon after the operation, cranial infection developed that required definitive drainage system and ventriculoperitoneal shunt had to be implanted. In further complicated clinical course, after four years on corticosteroid therapy (corticosteroid dependent sarcoidosis), he had to be urgently operated on because of significant ventricular catheter adhesions, but several days after the operation he died in coma because of progressive brain edema not responding to treatment. As hydrocephalus due to neurosarcoidos...
Source: Acta Clinica Croatica - September 30, 2021 Category: General Medicine Authors: Dragana Jovanovi ć Dana Gruji čić Mihailo Stjepanovi ć Spasoje Popevi ć Milica Konti ć Violeta Vu činić Mihailović Source Type: research
