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Infectious Disease: Zika Virus
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Total 31 results found since Jan 2013.
Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study
by Jose Xavier-Neto, Murilo Carvalho, Bruno dos Santos Pascoalino, Alisson Campos Cardoso, Ângela Maria Sousa Costa, Ana Helena Macedo Pereira, Luana Nunes Santos, Ângela Saito, Rafael Elias Marques, Juliana Helena Costa Smetana, Silvio Roberto Consonni, Carla Bandeira, Vivian Vasconcelos Costa, Marcio Chaim Bajgelman, Paulo Sérgio Lopes de Oliveira, Marli Tenorio Cordeiro, Laura Helen a Vega Gonzales Gil, Bianca Alves Pauletti, Daniela Campos Granato, Adriana Franco Paes Leme, Lucio Freitas-Junior, Carolina Borsoi Moraes Holanda de Freitas, Mauro Martins Teixeira, Estela Bevilacqua, Kleber Franchini
The teratogenic me...
Source: PLoS Neglected Tropical Diseases - February 22, 2017 Category: Tropical Medicine Authors: Jose Xavier-Neto Source Type: research
Hydrocephalus: New Complication of Congenital Zika Syndrome Hydrocephalus: New Complication of Congenital Zika Syndrome
First reports of hydrocephalus as a complication of congenital Zika syndrome have led to recommendations that monitoring for this condition be part of the standard care of infants exposed to ZIka.Medscape Medical News
Source: Medscape Medical News Headlines - November 23, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Association of Severe Hydrocephalus With Congenital Zika Syndrome
This case series describes clinical and imaging findings in 24 infants born with congenital Zika syndrome who developed hydrocephalus.
Source: JAMA Neurology - November 19, 2018 Category: Neurology Source Type: research
The chasm between public health and reproductive research: what history tells us about Zika virus
Abstract
Zika transmission from mother to fetus and its possible sexual transmission have become a media focus in the past months as a major public health concern. While mother-to-fetus transmission, fetal neurologic manifestations or sexual transmission have never been documented for this virus before, other viruses that belong to the same family are very well known to reproductive health workers, clinicians, and researchers. As a member of Flaviviridae family, including hepatitis C and bovine viral diarrhea virus (BVDV), Zika’s pathogenesis may have some parallels with these infections which may pose future qu...
Source: Journal of Assisted Reproduction and Genetics - March 4, 2016 Category: Reproduction Medicine Source Type: research
Confirmed case of Zika virus congenital infection, Spain, March 2016
We describe Zika virus (ZIKV) vertical transmission in an imported case in Spain, in a 17-week pregnant woman. ZIKV IgG, IgM and RNA were detected in serum in week 17. At 19 weeks, ultrasound scan revealed fetal malformations and ZIKV was detected in the amniotic fluid. Pregnancy was terminated at week 21; autopsy of the fetus revealed bilateral hydrocephalus, brain microcalcifications and arthrogryposis multiplex congenita. ZIKV was detected in the umbilical cord and brain tissue.
Source: Eurosurveillance - June 16, 2016 Category: Infectious Diseases Source Type: research
Clinical and Imaging Findings in an Infant With Zika Embryopathy
We present the first congenital ZIKV infection in the United States, confirmed by high ZIKV immunoglobulin M antibody titers in serum and cerebrospinal fluid. The phenotypic characteristics of the patient fall within fetal brain disruption sequence, suggesting impaired brain development in the second half of gestation. Brain imaging revealed an almost agyric brain with diffuse parenchymal calcifications, hydrocephalus ex vacuo, and cerebellar hypoplasia. Ophthalmologic examination revealed macular pigment stippling and optic nerve atrophy. Liver, lungs, heart, and bone marrow were not affected. The patient had progressive ...
Source: Clinical Infectious Diseases - August 23, 2016 Category: Infectious Diseases Authors: Culjat, M., Darling, S. E., Nerurkar, V. R., Ching, N., Kumar, M., Min, S. K., Wong, R., Grant, L., Melish, M. E. Tags: EMERGING INFECTIONS Source Type: research
Origin of the Zika virus revealed: a historical journey across the world
ConclusionsAlthough there was no evidence of the circulation of ZIKV in the Western hemisphere prior to 2014, the global spread of Stegomyia aegypti and increases in urban populations and international travel have fostered its evolution. Adherence to current guidelines for the prevention of ZIKV transmission is especially relevant in regions experiencing ongoing outbreaks. Concern for microcephaly in newborns warrants further investigation into the potential long‐term effects of ZIKV infection, especially in relation to reproductive health and mother–fetus transmission.
Source: International Journal of Dermatology - September 20, 2016 Category: Dermatology Authors: Stephanie Mlacker, Golsa Shafa, Adam S. Aldahan, Vidhi V. Shah, Sahal Samarkandy, Keyvan Nouri Tags: Tropical Medicine Rounds Source Type: research
Prenatal Ultrasound Findings of Pregnancy Associated with Zika Virus Infection
Publication date: Available online 25 September 2016 Source:Journal of Medical Ultrasound Author(s): Yen-Ni Chen, Chih-Ping Chen, Chen-Ju Lin, Shin-Wen Chen The outbreak of Zika virus followed by an increase in cases of fetal microcephaly in Brazil in 2015 has raised the concern of the association of Zika virus infection with fetal microcephaly and other central nervous system (CNS) malformations. Most patients with Zika virus infection are asymptomatic. However, according to a previous report, the most common symptom in pregnant women with Zika virus infection and fetal microcephaly is rash. Reported prenatal ultrasound ...
Source: Journal of Medical Ultrasound - September 25, 2016 Category: Radiology Source Type: research
Rapid Molecular Detection of Zika Virus in Acute-Phase Urine Samples Using the Recombinase Polymerase Amplification Assay
Conclusions
To our knowledge, the developed RT-RPA assay is the first sensitive rapid molecular assay applied on field samples for the detection of ZIKV in 15 minutes, which could be implemented at the point of need in a mobile suitcase laboratory 5 to make testing of pregnant women available directly in rural settings. Moreover, combining it with the developed dengue 6, chikungunya 7 and Sigma 8 RT-RPA assays will allow its use during outbreak investigations. Sigma virus infects exclusively dipterans, which is a good candidate to be used in the future as an extraction and RPA reaction control.
Data Availability Statement...
Source: PLOS Currents Outbreaks - January 25, 2017 Category: Epidemiology Authors: abdelwahed Source Type: research
For Brazil ’ s Zika Families, a Life of Struggle and Scares
In the impoverished northeast, devoted parents live around the needs of children whose grave disabilities are only beginning to be understood.
Source: NYT Health - March 11, 2017 Category: Consumer Health News Authors: PAM BELLUCK and TANIA FRANCO Tags: Zika Virus Brazil Microcephaly Hydrocephalus Seizures (Medical) Recife (Brazil) Birth Defects Families and Family Life Source Type: news
No Brasil, beb ê s prisioneiros do zika s ã o envolvidos pelos cuidados dos seus pais
No empobrecido Nordeste do Brasil, dedicados e amorosos pais e m ã es vivem em fun ç ã o das necessidades dos filhos cujas graves defici ê ncias est ã o somente come ç ando a ser compreendidas.
Source: NYT Health - March 14, 2017 Category: Consumer Health News Authors: Por PAM BELLUCK and TANIA FRANCO Tags: Zika Virus Brazil Microcephaly Hydrocephalus Seizures (Medical) Recife (Brazil) Birth Defects Families and Family Life Source Type: news
Neurological impairment of the monozygotic twins with congenital infection presumed by Zika virus: Case report
Discussion: distinct neurological alterations in the monochorionic twins with an infection presumed by Zika virus may raise the hypothesis of the existence of predisposing factors or protection against this viral agent.Resumo Introdu ção: o aumento da incidência de microcefalia congênita no Brasil tem sido associado à epidemia do zika vírus. Este relato objetivou descrever o comprometimento neurológico de gêmeas monozigóticas presumidamente infectadas intra-útero pelo zika vírus durante a epidemia brasileira de 2015. Descrição do caso: gêmeas monozigóticas, nascidas a termo, com microcefalia congênita sever...
Source: Revista Brasileira de Saude Materno Infantil - May 28, 2018 Category: Midwifery Source Type: research
Clinical and epidemiological aspects of microcephaly in the state of Piau í, northeastern Brazil, 2015-2016.
CONCLUSIONS: The state of Piauí, like others in the northeastern region, faced an epidemic of congenital microcephaly between 2015 and 2016, presumably related to congenital Zika virus infection, more intense in the capital. Current challenges include the improvement of vector control, basic research, scaling-up of diagnostic tools for pre-natal screening of Zika virus, vaccines, and health care for affected children.
PMID: 29963988 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - June 29, 2018 Category: Pediatrics Authors: Almeida IMLM, Ramos CV, Rodrigues DC, Sousa AC, Nascimento MLCAPCD, Silva MVBD, Batista FMA, Santos JPD, Oliveira RS, Nobre FAF, Xavier SCDC, Carvalho-Costa FA Tags: J Pediatr (Rio J) Source Type: research
Zika Virus and Other Emerging Arboviral Central Nervous System Infections
This article reviews the epidemiology, clinical features, and diagnosis of Zika virus–associated neurologic illness and briefly reviews features of West Nile virus and Japanese encephalitis virus.
RECENT FINDINGS
Zika virus has emerged as a significant human pathogen in recent years. In 2015, it began to cause large outbreaks of febrile rash illness in South America and the Caribbean. During these large Zika virus outbreaks, a significant increase in the incidence of GBS was also observed in multiple countries/territories. Zika virus–associated GBS has several unique features, including a relatively short interval b...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2018 Category: Neurology Tags: Review Articles Source Type: research
Updated Imaging Findings in Congenital Zika Syndrome: A Disease Story That is Still Being Written
In congenital Zika virus syndrome (CZS), the most frequent radiological findings are calcifications in the cortical–white matter junction and malformations of cortical development (pachygyria or polymicrogyria, which occur predominantly in the frontal lobes, or a simplified gyral pattern), ventriculomegaly, enlargement of the cisterna magna and the extra-axial subarachnoid space, corpus callosum abnormalities, and reduced brain volume. This syndrome can also result in a decrease in the brainstem and cerebellum volumes and delayed myelination. Infants with CZS may show venous thrombosis and lenticulostriate vasculopathies...
Source: Topics in Magnetic Resonance Imaging - February 1, 2019 Category: Radiology Tags: Review Articles Source Type: research
