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Total 129 results found since Jan 2013.
Dendritic and Synaptic Degeneration in Pyramidal Neurons of the Sensorimotor Cortex in Neonatal Mice With Kaolin-Induced Hydrocephalus
This study evaluated the effect of hydrocephalus on dendritic arborization and synaptic structure of the pyramidal neurons of the sensorimotor cortex of neonatal hydrocephalic mice. Sterile kaolin suspension (0.01 ml of 250 mg/mL) was injected intracisternally into day old mice. Control animals mice received sham injections. Pups were weighed and sacrificed on postnatal days (PND) 7, 14 and 21. Fixed brain tissue blocks were silver impregnated using a modified Golgi staining technique and immunolabeled with synaptophysin to determine dendritic morphology and synaptic integrity respectively. Data were analyzed using ANOVA a...
Source: Frontiers in Neuroanatomy - April 23, 2019 Category: Neurology Source Type: research
Endoscopic third ventriculostomy for pediatric tumor-associated hydrocephalus.
CONCLUSIONS: Treatment of tumor-related hydrocephalus with ETV is common and is warranted in select pediatric patient populations. Failure rates are overall similar to those of VPS for tumor-associated hydrocephalus.
PMID: 31896082 [PubMed - in process]
Source: Neurosurgical Focus - December 31, 2019 Category: Neurosurgery Authors: Sherrod BA, Iyer RR, Kestle JRW Tags: Neurosurg Focus Source Type: research
Frequency and treatment of hydrocephalus prior to and after posterior fossa tumor surgery in adult patients
ConclusionThe frequency of hydrocephalus prior to posterior fossa tumor surgery in adult patients is 21.4% and therefore much lower than in respective reports of pediatric patients. The risk of persistent hydrocephalus and newly developed hydrocephalus after tumor surgery was very low, too (5.7 and 2.1%, respectively). An ETV is not justified in every adult patient prior to posterior fossa tumor surgery.
Source: Acta Neurochirurgica - April 12, 2018 Category: Neurosurgery Source Type: research
Ventriculoperitoneal Shunt versus Endoscopic Third Ventriculostomy in the treatment of Obstructive Hydrocephalus in Pediatric Midline Posterior Fossa tumors
ConclusionThe shorter duration of surgery, the lower incidence of morbidity, the absence of mortality, the lower incidence of procedure failure of endoscopic third ventriculostomy as compared to ventriculoperitoneal shunt, and the significant advantage of not becoming shunt dependent make endoscopic third ventriculostomy to be recommended as the first choice in the treatment of pediatric patients with marked obstructive hydrocephalus due to posterior fossa tumors. It is a preliminary, simple, safe, effective, physiological, minimally invasive procedure for the relief of elevated intracranial pressure before direct tumor removal.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Lower rates of symptom recurrence and surgical revision after primary compared with secondary endoscopic third ventriculostomy for obstructive hydrocephalus secondary to aqueductal stenosis in adults.
CONCLUSIONS Patients with obstructive hydrocephalus due to aqueductal stenosis exhibit symptomatic improvement after ETV, with a relatively low failure rate. Patients with a primary history of shunt placement who undergo ETV as a secondary intervention are at increased risk of symptom recurrence and need for surgical revision post-ETV.
PMID: 26517771 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 30, 2015 Category: Neurosurgery Authors: Sankey EW, Goodwin CR, Jusué-Torres I, Elder BD, Hoffberger J, Lu J, Blitz AM, Rigamonti D Tags: J Neurosurg Source Type: research
Surgical Management of Non-Communicating Hydrocephalus in Patients: Meta-Analysis and Comparison of Endoscopic Third Ventriculostomy and Ventriculoperitoneal Shunt
Objective: We performed a meta-analysis of reported series of endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) for non-communicating hydrocephalus to determine whether comparisons between the outcomes in ETV and VPS approaches are valid.
Methods: Online databases were searched for articles reporting quantifiable outcome data published between 1990 and 2014 pertaining to the surgical treatment of non-communicating hydrocephalus, with no language restrictions. Eight articles meeting predetermined criteria were included. Data were pooled for 5 surgical outcome measures.
Results: Our literature searc...
Source: Journal of Craniofacial Surgery - March 1, 2015 Category: Surgery Tags: Clinical Studies Source Type: research
P2-2-2 * two cases of total blindness and hydrocephalus caused by carcinomatous meningitis of gastric cancer
Discussion: Since the hydrocephalus accompanied by gastric cancer with meningeal carcinomatosis usually progress rapidly, prompt ventricular drainage is useful and mandatory to overcome oncology emergency such as progressive hydrocephalus with total blindness and respiratory failure.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Naganuma, A., Uehara, S., Hayashi, E., Hoshino, T., Kudo, T., Takagi, H., Ishihara, H., Ishiguro, K., Tanaka, T., Yoshida, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research
P2-2-2 * two cases of total blindness and hydrocephalus caused by carcinomatous meningitis of gastric cancer
Discussion: Since the hydrocephalus accompanied by gastric cancer with meningeal carcinomatosis usually progress rapidly, prompt ventricular drainage is useful and mandatory to overcome oncology emergency such as progressive hydrocephalus with total blindness and respiratory failure.
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Naganuma, A., Uehara, S., Hayashi, E., Hoshino, T., Kudo, T., Takagi, H., Ishihara, H., Ishiguro, K., Tanaka, T., Yoshida, T. Tags: Poster Session (Poster presentations categorized by each organ) Source Type: research
Endoscopic third ventriculostomy and ventriculoperitoneal shunt for patients with noncommunicating hydrocephalus: A PRISMA-compliant meta-analysis
Background:
The surgical methods of endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VS) for patients with noncommunicating hydrocephalus have rapidly increased in the past 2 decades. However, there is controversy regarding the efficacy and safety of these 2 surgical methods for noncommunicating hydrocephalus. The purpose of this study was to identify whether ETV is safer and more efficacious than VS for patients with noncommunicating hydrocephalus.
Methods:
We performed electronic searches in PubMed, Embase, China National Knowledge Internet, and the Cochrane Library to identify studies publishe...
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Natural History, Treatment Outcomes and Quality of Life in Idiopathic Normal Pressure Hydrocephalus (iNPH)
Conclusions: The natural history for untreated patients with iNPH is poor, with both increased mortality and morbidity. It is strongly recommended that practitioners follow established guidelines to select patients with suspected iNPH while using objective measures of gait, balance, and cognition for consideration of treatment with a CSF shunt. Other factors such as patient-related medical comorbidities or frailty may need to be factored into the decision-making process before surgical treatment is offered. As a rule, failure to select patients based on the identified guidelines will result in a significantly lower positiv...
Source: Neurology India - December 11, 2021 Category: Neurology Authors: Albert M Isaacs Mark Hamilton Source Type: research
Role of surgical procedures (VP shunt and ETV) in tuberculous meningitis with hydrocephalus (TBMH): A systematic review
Conclusion: There was a significant difference in the average percentage of good outcome after ETV than VPS, and complication rate was also slightly lower after ETV than VPS during the chronic phase of illness. So during the acute phase of illness VPS placement is preferred whereas in the chronic burnout phase ETV is preferred because poor anatomy leads to more complications with ETV during the acute phase of the disease.
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Bharat Bhushan Vijay Sardana Prashant Shringi Seeta Ram Yadav Dilip Maheshwari Source Type: research
Comparison of outcomes between patients with idiopathic normal pressure hydrocephalus who received a primary versus a salvage shunt
Publication date: Available online 18 February 2016 Source:Journal of Clinical Neuroscience Author(s): Dane Moran, Alice Hung, Sharif Vakili, Hugo Fialho, Lee Jeon, Eric W. Sankey, Ignacio Jusué-Torres, Jennifer Lu, C. Rory Goodwin, Benjamin D. Elder, Daniele Rigamonti Placement of a ventriculoperitoneal (VP) shunt is the treatment of choice for communicating hydrocephalus; however, the extent to which VP shunting is able to relieve symptoms in patients who had previously been treated with cerebrospinal fluid diverting therapy at an outside institution remains unclear. A retrospective review of patients with ...
Source: Journal of Clinical Neuroscience - February 20, 2016 Category: Neuroscience Source Type: research
Is Endoscopic Third Ventriculostomy a Feasible Option or Ventriculoperitoneal Shunt a Safer Bet for the Treatment of Posttraumatic Hydrocephalus ? A Gap Time Model-based Algorithm
Conclusions: VPS is an effective modality for the management of PTH and has a much lower failure rate as compared to ETV. However, ETV can be considered as a salvage procedure in difficult situations of recurrent shunt malfunction or infection.
Source: Neurology India - October 27, 2020 Category: Neurology Authors: Raghavendra Sharma Ravi Sharma Vivek Tandon Manoj Phalak Kanwaljeet Garg Manmohan Singh Deepak Gupta Deepak Agrawal Sarat P Chandra Shashank Sharad Kale V Sreenivas Source Type: research
Endoscopic third ventriculostomy before surgery of third ventricle and posterior fossa tumours decreases the risk of secondary hydrocephalus and early postoperative complications
AbstractEndoscopic third ventriculostomy (ETV) is an effective treatment for obstructive hydrocephalus (HCP) at the level of third or fourth ventricle. To date, there is no consensus regarding its role as intervention preceding the operation of tumour removal. The aim of this prospective open-label controlled study is to assess if ETV prevents secondary HCP after tumour removal and if ETV influences the early results of tumour surgery. The study was performed on 68 patients operated for tumours of the third ventricle and posterior fossa. In 30 patients, ETV was performed several days before tumour removal, while in 38 pati...
Source: Neurosurgical Review - July 22, 2021 Category: Neurosurgery Source Type: research
