Filtered By:
Procedure: Shunt for Hydrocephalus

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 3722 results found since Jan 2013.

An update on research priorities in hydrocephalus: overview of the third National Institutes of Health-sponsored symposium "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes".
Abstract Building on previous National Institutes of Health-sponsored symposia on hydrocephalus research, "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes" was held in Seattle, Washington, July 9-11, 2012. Plenary sessions were organized into four major themes, each with two subtopics: Causes of Hydrocephalus (Genetics and Pathophysiological Modifications); Diagnosis of Hydrocephalus (Biomarkers and Neuroimaging); Treatment of Hydrocephalus (Bioengineering Advances and Surgical Treatments); and Outcome in Hydrocephalus (Neuropsychological and Neurological). International experts gave plenary ...
Source: Journal of Neurosurgery - June 19, 2015 Category: Neurosurgery Authors: McAllister JP, Williams MA, Walker ML, Kestle JR, Relkin NR, Anderson AM, Gross PH, Browd SR, Hydrocephalus Symposium Expert Panel Tags: J Neurosurg Source Type: research

Alzheimer CSF biomarkers may be misleading in normal-pressure hydrocephalus
Conclusions: In the setting of hydrocephalus when the brain is compressed, a decrease in interstitial space and APP protein fragment drainage into the CSF may be impeded, resulting in low levels of all APP fragments and tau proteins, which has been reported. Shunting, which decompresses the brain, would create more room for the interstitial space to increase and protein waste fragments to drain into the CSF. In fact, CSF proteins increase after shunting. CSF biomarkers in pre-shunt NPH have low Aβ42 and tau protein levels, providing misleading information to distinguish NPH from comorbid NPH plus AD.
Source: Neurology - October 20, 2014 Category: Neurology Authors: Graff-Radford, N. R. Tags: Hydrocephalus, Cerebrospinal Fluid MEDICAL HYPOTHESIS Source Type: research

Intracranial pressure in hydrocephalus: impact of shunt adjustments and body positions
Conclusions Changing from a supine to an upright position reduced ICP while AMP only increased at trend level. Lowering of the shunt valve opening pressure decreased ICP and AMP but the difference in mean ICP in vivo between the highest and lowest opening pressures was less than half that previously observed in vitro.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2015 Category: Neurosurgery Authors: Farahmand, D., Qvarlander, S., Malm, J., Wikkelso, C., Eklund, A., Tisell, M. Tags: Hydrocephalus, Radiology Neurosurgery Source Type: research

Preoperative and postoperative 1H-MR spectroscopy changes in frontal deep white matter and the thalamus in idiopathic normal pressure hydrocephalus
Conclusions Normalisation of thalamic tNA and NAA could not be detected postoperatively. The increased tCho and decreased mIns in the FDWM postoperatively might relate to clinical improvement.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 10, 2013 Category: Neurosurgery Authors: Lundin, F., Tisell, A., Leijon, G., Leinhard, O. D., Davidsson, L., Gronqvist, A., Wikkelso, C., Lundberg, P. Tags: Drugs: CNS (not psychiatric), Hydrocephalus, Radiology Neurosurgery Source Type: research

The European iNPH Multicentre Study on the predictive values of resistance to CSF outflow and the CSF Tap Test in patients with idiopathic normal pressure hydrocephalus
Conclusions Rout and the results of the CSF TT did not correlate with outcome after 12 months. Rout and CSF TT can be used for selecting patients for shunt surgery but not for excluding patients from treatment. Trial registration The study has been registered at clinicaltrials.gov, identifier NCT00874198.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 8, 2013 Category: Neurosurgery Authors: Wikkelso, C., Hellstrom, P., Klinge, P. M., Tans, J. T. J., on behalf of the European iNPH Multicentre Study Group Tags: Hydrocephalus, Radiology Neurosurgery Source Type: research

Pulsatility in CSF dynamics: pathophysiology of idiopathic normal pressure hydrocephalus
Conclusions The pulsatility curve was not modified by shunt surgery, while the baseline position was shifted along the curve. Observed differences between gait improvers and non-improvers support cardiac related ICP pulsations as a component of INPH pathophysiology.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 9, 2013 Category: Neurosurgery Authors: Qvarlander, S., Lundkvist, B., Koskinen, L.-O. D., Malm, J., Eklund, A. Tags: Hydrocephalus, Radiology Movement disorders Source Type: research

A randomised trial of high and low pressure level settings on an adjustable ventriculoperitoneal shunt valve for idiopathic normal pressure hydrocephalus: results of the Dutch evaluation programme Strata shunt (DEPSS) trial
Conclusions On the basis of this multicentre prospective randomised trial it is to be recommended to treat patients with INPH with a shunt with an adjustable valve, preset at the highest opening pressure and lowered until clinical improvement or radiological signs of overdrainage occur although slower improvement and more shunt adjustments might be the consequence.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 9, 2013 Category: Neurosurgery Authors: Delwel, E. J., de Jong, D. A., Dammers, R., Kurt, E., van den Brink, W., Dirven, C. M. F. Tags: Hydrocephalus, Infection (neurology), Radiology Neurosurgery Source Type: research

Safety and efficacy of gravitational shunt valves in patients with idiopathic normal pressure hydrocephalus: a pragmatic, randomised, open label, multicentre trial (SVASONA)
Conclusions Implanting a gravitational rather than another type of valve will avoid one additional overdrainage complication in about every third patient undergoing VP shunting for iNPH.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 8, 2013 Category: Neurosurgery Authors: Lemcke, J., Meier, U., Muller, C., Fritsch, M. J., Kehler, U., Langer, N., Kiefer, M., Eymann, R., Schuhmann, M. U., Speil, A., Weber, F., Remenez, V., Rohde, V., Ludwig, H.-C., Stengel, D. Tags: Open access, Headache (including migraine), Hydrocephalus, Infection (neurology), Pain (neurology) Neurosurgery Source Type: research

Natural course of idiopathic normal pressure hydrocephalus
Conclusions The natural course of iNPH is symptom progression over time, with worsening in gait, balance and cognitive symptoms. This deterioration is only partially reversible. To maximise the benefits of shunt treatment, surgery should be performed soon after diagnosis.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 10, 2014 Category: Neurosurgery Authors: Andren, K., Wikkelso, C., Tisell, M., Hellstrom, P. Tags: Hydrocephalus Neurosurgery Source Type: research

Protocolizing the Workup for Idiopathic Normal Pressure Hydrocephalus Improves Outcomes
Conclusions Implementing an INPH Protocol leads to standardized and more extensive assessment and better patient selection for and subsequent outcomes from shunting, specifically regarding gait.
Source: Neurology Clinical Practice - August 9, 2021 Category: Neurology Authors: Acosta, L. M. Y., Stubblefield, K., Conwell, T., Espaillat, K., Koons, H., Konrad, P., Fang, J., Kirshner, H., Davis, T. Tags: Hydrocephalus, Diagnostic test assessment, All Clinical Neurology, Gait disorders/ataxia, Assessment of cognitive disorders/dementia Research Source Type: research

Dendritic and Synaptic Degeneration in Pyramidal Neurons of the Sensorimotor Cortex in Neonatal Mice With Kaolin-Induced Hydrocephalus
This study evaluated the effect of hydrocephalus on dendritic arborization and synaptic structure of the pyramidal neurons of the sensorimotor cortex of neonatal hydrocephalic mice. Sterile kaolin suspension (0.01 ml of 250 mg/mL) was injected intracisternally into day old mice. Control animals mice received sham injections. Pups were weighed and sacrificed on postnatal days (PND) 7, 14 and 21. Fixed brain tissue blocks were silver impregnated using a modified Golgi staining technique and immunolabeled with synaptophysin to determine dendritic morphology and synaptic integrity respectively. Data were analyzed using ANOVA a...
Source: Frontiers in Neuroanatomy - April 23, 2019 Category: Neurology Source Type: research

What Clinical Signs Can Be Associated With Benign External Hydrocephalus?
Discussion Hydrocephalus is an abnormal accumulation of cerebrospinal fluid (CSF) in the ventricles and/or subarachnoid spaces. External hydrocephalus is a communicating hydrocephalus often defined as the patient having a rapidly enlarging head circumference (HC) and enlargement of the subarachnoid spaces especially over the frontal lobes with normal or moderately enlarged ventricles. Benign external hydrocephalus (BEH) is a self-limited external hydrocephalus that occurs during infancy and resolves spontaneously in childhood, usually by age 2 years, that is felt to not cause significant problems. It was first described by...
Source: PediatricEducation.org - October 2, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Myelomeningocele-associated hydrocephalus: nationwide analysis and systematic review.
CONCLUSIONS: From 1998 to 2014, hydrocephalus treatment has become more delayed and the number of hydrocephalic MMC patients not treated on initial inpatient stay has increased. Meta-analysis demonstrated that shunt malfunction and infection rates do not differ between delayed and simultaneous hydrocephalus treatment. PMID: 31574479 [PubMed - in process]
Source: Neurosurgical Focus - September 30, 2019 Category: Neurosurgery Authors: McCarthy DJ, Sheinberg DL, Luther E, McCrea HJ Tags: Neurosurg Focus Source Type: research

Prognostic Utility of Disproportionately Enlarged Subarachnoid Space Hydrocephalus in Idiopathic Normal Pressure Hydrocephalus Treated with Ventriculoperitoneal Shunt Surgery: A Systematic Review and Meta-analysis ADULT BRAIN
CONCLUSIONS: Our meta-analysis demonstrated a relatively low prevalence of disproportionately enlarged subarachnoid space hydrocephalus in idiopathic normal pressure hydrocephalus and a poor diagnostic performance for treatment response.
Source: American Journal of Neuroradiology - August 11, 2021 Category: Radiology Authors: Park, H. Y., Park, C. R., Suh, C. H., Kim, M. J., Shim, W. H., Kim, S. J. Tags: ADULT BRAIN Source Type: research

Hydrocephalus Associated with Posterior Fossa Tumors: How to Manage Effectively ?
Conclusions: Hydrocephalus associated with PFT affects the quality of life of patients with such lesions. Routine preoperative CSF diversion is not necessary for the vast majority of patients with posterior fossa tumor-related hydrocephalus. A high index of suspicion and aggressive surveillance is required for the early identification and appropriate management of postresection hydrocephalus. Future studies are needed to address several unanswered questions pertaining to the management of this condition.
Source: Neurology India - December 11, 2021 Category: Neurology Authors: Natarajan Muthukumar Source Type: research