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Specialty: Microbiology

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Total 178 results found since Jan 2013.

Coarse graining the human gut microbiome
Cell Host Microbe. 2023 Jul 12;31(7):1076-1078. doi: 10.1016/j.chom.2023.06.001.ABSTRACTThe composition of the human gut microbiome is heterogeneous across people. However, if you squint, co-abundant microbial genera emerge, accounting for much of this ecological variability. In this issue of Cell Host & Microbe, Frioux et al. provide a workflow for identifying these bacterial guilds, or "enterosignatures."PMID:37442093 | DOI:10.1016/j.chom.2023.06.001
Source: Cell Host and Microbe - July 13, 2023 Category: Microbiology Authors: Christian Diener Sean M Gibbons Source Type: research

Risk factors and outcomes of cerebrospinal fluid overdrainage in HIV-negative patients with cryptococcal meningitis after the ventriculoperitoneal shunting procedure
Conclusions CSF overdrainage after the VP shunt procedure is not rare, especially in patients with a high-risk of cryptococcal meningitis who also have a prolonged duration of hydrocephalus and/or IICP.
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Paediatric bacterial meningitis in the USA: outcomes and healthcare resource utilization of nosocomial versus community-acquired infection.
Conclusion. In multivariable analysis, nosocomial infections were associated with significantly higher long-term costs up to 2 years post-infection. Hydrocephalus, intracranial epidural abscess and cerebral oedema were the most common complications, and lumbar punctures and ventricular catheter placement were the most common neurosurgical procedures. This study represents the first nation-wide, longitudinal comparison of the outcomes and considerable HCRU of nosocomial versus community-acquired paediatric BM, including characterization of complications and procedures contributing to the high costs of these infections. ...
Source: Journal of Medical Microbiology - November 18, 2020 Category: Microbiology Authors: Adil SM, Hodges SE, Charalambous LT, Kiyani M, Liu B, Lee HJ, Parente BA, Perfect JR, Lad SP Tags: J Med Microbiol Source Type: research

Racemose neurocysticercosis simulating tuberculous meningitis
We report a patient with racemose neurocysticercosis, highlighting the diagnostic and management issues. A 37-year-old male had headaches, fever, and seizures for 8  months. He had a positive tuberculin test, cerebrospinal fluid pleocytosis, and hydrocephalus and exudates on MRI. His symptoms rapidly resolved following antitubercular and prednisolone treatment. After 2 months, he was readmitted with headache and vomiting, and his brain MRI revealed communicat ing hydrocephalus with a cyst in the lateral ventricle and subarachnoid space, which was confirmed as neurocysticercosis on the third ventriculostomy. The patient w...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 22, 2022 Category: Microbiology Source Type: research

Childhood tuberculosis in southern Taiwan, with emphasis on central nervous system complications.
CONCLUSIONS: Findings suggest that positive exposure history and suspicious clinical presentations are important clues for further confirmatory laboratory and image studies in childhood TB. CNS TB usually presented as part of disseminated TB in children. Early diagnosis and treatment may lead to favorable outcomes in CNS TB. PMID: 23927821 [PubMed - as supplied by publisher]
Source: Journal of Microbiology, Immunology, and Infection - August 5, 2013 Category: Microbiology Authors: Cho YH, Ho TS, Wang SM, Shen CF, Chuang PK, Liu CC Tags: J Microbiol Immunol Infect Source Type: research

Pathophysiology of neonatal acute bacterial meningitis.
Abstract Neonatal meningitis is a severe acute infectious disease of the central nervous system (CNS) and an important cause of morbidity and mortality worldwide. The inflammatory reaction involves the meninges, the subarachnoid space and the brain parenchymal vessels and contributes to neuronal injury. It may lead to deafness, blindness, cerebral palsy, seizures, hydrocephalus or cognitive impairment in approximately 25% to 50% of survivors. Bacterial pathogens may reach the blood-brain barrier and be recognised by antigen-presenting cells through the binding of Toll-like receptors. They induce the activation of ...
Source: Journal of Medical Microbiology - August 14, 2013 Category: Microbiology Authors: Barichello T, Fagundes GD, Generoso JS, Elias SG, Simões LR, Teixeira AL Tags: J Med Microbiol Source Type: research

Childhood tuberculosis in southern Taiwan, with emphasis on central nervous system complications
Conclusion Findings suggest that positive exposure history and suspicious clinical presentations are important clues for further confirmatory laboratory and image studies in childhood TB. CNS TB usually presented as part of disseminated TB in children. Early diagnosis and treatment may lead to favorable outcomes in CNS TB.
Source: Journal of Microbiology, Immunology and Infection - November 3, 2014 Category: Microbiology Source Type: research

Coagulase-negative staphylococci: Emerging pathogen in central nervous system shunt infection
Preeti Lata Bhatia, Sunil Lilani, Ritesh Shirpurkar, Chhaya Chande, Shrikant Joshi, Abhay ChowdharyIndian Journal of Medical Microbiology 2017 35(1):120-123 Central nervous system (CNS) shunts are commonly used to treat patients with hydrocephalus. Its placement is associated with increased risk of infection. The study was intended to evaluate infection rate associated with CNS shunt surgeries and identify risk factors for shunt infection. The frequency and characterisation of aetiological agents along with their antibiotic resistance pattern were also studied. A prospective study of 86 patients who underwent 97 surgeries...
Source: Indian Journal of Medical Microbiology - March 15, 2017 Category: Microbiology Authors: Preeti Lata Bhatia Sunil Lilani Ritesh Shirpurkar Chhaya Chande Shrikant Joshi Abhay Chowdhary Source Type: research

Genotyping of Toxoplasma gondii strain directly from human CSF samples of congenital toxoplasmosis clinical case.
This report describes a case of congenital toxoplasmosis in a newborn in Southern Italy. A pregnant mother had been admitted at the 20th week of her pregnancy on account of pharyngodynia and laterocervical lymphadenopathy. Although serological testing of the mother's serum documented a seroconversion with positive IgG and IgM anti-Toxoplasma antibodies during II trimester, the woman refused to perform prenatal diagnosis for congenital toxoplasmosis. Fetal ultrasound scan already showed mild asymmetrical triventricular hydrocephaly and cerebral calcifications. After birth, real-time PCR on cerebrospinal fluid and blood samp...
Source: New Microbiologica - April 4, 2017 Category: Microbiology Tags: New Microbiol Source Type: research

Magnetic resonance imaging study of cryptococcal neuroradiological lesions in HIV-negative cryptococcal meningitis
In conclusion, the main pattern of cryptococcosis-related lesions on MR scanning differ between non-HIV- and HIV-positive patients with CM. The presence of CM-related lesions was significantly associated with predictors for poor outcome. Neuroimaging on MR scanning is a useful tool to evaluate the initial severity and prognosis of CM without HIV infection.
Source: European Journal of Clinical Microbiology and Infectious Diseases - July 24, 2017 Category: Microbiology Source Type: research

Neurobrucellosis: diagnostic and clinical management of an atypical case.
We describe an atypical case of brucellar meningitis with many stroke-like signs, think as recurrent cerebrovascular events and treated with antithrombotic therapy, but without meningeal syndrome. PMID: 29384559 [PubMed - as supplied by publisher]
Source: New Microbiologica - February 1, 2018 Category: Microbiology Tags: New Microbiol Source Type: research

CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report
In conclusion, this case was presented to emphasize the consideration of CARD9 deficiency in case of persistent invasive fungal infection or recurrent invasive fungal infection after treatment despite effective antifungal treatment in children and adults who do not have known risk factors for invasive fungal infections.PMID:34666665 | DOI:10.5578/mb.20219717
Source: Mikrobiyoloji Bulteni - October 20, 2021 Category: Microbiology Authors: Tuba Kuruo ğlu Merve Çelik Fatih Çelmeli Esra Tanyel Source Type: research