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Endoscopic biopsy for the diagnosis of neurosarcoidosis at the fourth ventricle outlet with hydrocephalus.
CONCLUSION: Endoscopic procedure is less invasive and more effective for biopsy of neurosarcoidosis with hydrocephalus, even if the lesion is located at the fourth ventricle outlet. PMID: 26682088 [PubMed]
Source: Surgical Neurology International - December 20, 2015 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Outcomes and risk factors of surgical management of thyroid eye disease-related diplopia
CONCLUSION: Strabismus surgery in TED patients resulted in a high success rate in reducing diplopia and improving ocular motility. The success rate was not negatively associated with previous therapies. Indeed, resolution of diplopia required more squint procedures in patients who have previously undergone to orbital decompression.PMID:35225021 | DOI:10.1177/11206721221083836
Source: European Journal of Ophthalmology - February 28, 2022 Category: Opthalmology Authors: Maria Paola Laezza Marina Concilio Mariapaola Giordano Vittoria Lanni Adriana Iuliano Diego Strianese Source Type: research

Characteristics of central nervous system tuberculosis in a low-incidence country: a series of 20 cases and a review of the literature.
Abstract Central nervous system tuberculosis (CNS-TB) is a devastating manifestation of tuberculosis (TB) caused by the hematogenous spread of Mycobacterium tuberculosis. Here, I present a retrospective analysis of 20 CNS-TB cases in Israel, a country with a low incidence of TB over an 11-year period (2000-2010). Most of the cases were those of African migrants, with an increased prevalence in adult females and in those with HIV coinfections. Clinical manifestations were usually non-specific, and miliary infiltrates were rare. Lymphocytic meningitis was frequent with bacteriological confirmation in 50% of the case...
Source: Japanese Journal of Infectious Diseases - January 25, 2014 Category: Infectious Diseases Authors: Daniele B Tags: Jpn J Infect Dis Source Type: research

Primary glioblastoma of the medulla spinalis: a report of three cases and review of the literature.
Abstract Primary spinal glioblastoma multiforme (spinal GBM) is not a very common entity. This paper presents an outline of this rare neoplasm, its clinical presentation, course, management and outcome and reports a 3-case series of spinal GBM. In this 3-case series with spinal GBM, one of the patients was operated for hydrocephalous 10 months later following the tumor surgery and another patient had cerebral metastasis after the surgery. In the postoperative period, two of the cases received radiotherapy and one received combined radiotherapy and chemotherapy with steroid therapy together following the tumor surg...
Source: Turkish Neurosurgery - December 7, 2013 Category: Neurosurgery Authors: Ozgiray E, Akay A, Ertan Y, Cagli S, Oktar N, Ozdamar N Tags: Turk Neurosurg Source Type: research

A case of idiopathic hypertrophic pachymeningitis presenting with chronic headache and multiple cranial nerve palsies: A case report
Rationale: Idiopathic hypertrophic pachymeningitis (IHP) is a rare condition, characterized by a chronic fibrosing inflammatory process usually involving either the intracranial or spinal dura mater, but rarely both. Here, we report a rare case of IHP affecting both the intracranial and spinal dura mater. We also discussed the diagnosis, management, and outcome of IHP. Patient concerns: We reviewed the case of a 60-year-old woman presenting with chronic headache, multiple cranial nerve palsies and gait disturbance. Magnetic resonance imaging (MRI) of her head revealed thickened and contrast-enhanced dura in the craniocerv...
Source: Medicine - July 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Major complications from radiotherapy following treatment for atypical meningiomas.
CONCLUSIONSThe postoperative management of patients with atypical meningioma continues to be defined, with questions remaining regarding timing of RT, dose, target delineation, and fractionation. Both of the patients in this study received fractionated RT, which included a greater volume of normal brain than more focal treatment options such as would be required by stereotactic radiosurgery (SRS). Further research is needed to compare SRS and fractionated RT for the management of patients with grade II meningiomas. The more focused nature of SRS may make this a preferred option in certain cases of focal recurrence. PM...
Source: Neurosurgical Focus - May 31, 2019 Category: Neurosurgery Authors: Dawley T, Rana Z, Abou-Al-Shaar H, Goenka A, Schulder M Tags: Neurosurg Focus Source Type: research

Postnatal steroid therapy is associated with autism spectrum disorder in children and adolescents of very low birth weight infants.
CONCLUSIONS: This study suggests a significant association between postnatal steroid therapy and ASD in VLBW infants. This possible association should be considered in future studies evaluating potential risk factors for ASD in preterm infants. PMID: 31791046 [PubMed - as supplied by publisher]
Source: Pediatric Research - December 1, 2019 Category: Pediatrics Authors: Michael D, Kuint J, Lerner-Geva L, Zaslavsky-Paltiel I, Shmuel RR, Chodick G, Shalev V, Reichman B, Israel Neonatal Network Tags: Pediatr Res Source Type: research

Resolution of Radiation-Induced Necrosis in Arteriovenous Malformation with Bevacizumab: A Case Report and Review of Current Literature
Stereotactic radiosurgery (SRS) is a proven treatment modality for inoperable arteriovenous malformations (AVMs). However, the rate of radiation-induced necrosis (RIN) is as high as 10%. A 6-year-old female patient presented with severe headache, emesis, and syncope, and workup revealed a Spetzler-Martin grade 4 AVM with intraventricular hemorrhage and hydrocephalus. The patient underwent a right frontal ventriculostomy followed by a linear accelerator-based SRS of 16.9 Gy. At 19 years, she developed progressive neurological symptoms. Diagnostic magnetic resonance imaging (MRI) revealed a recurrent parietal AVM nidus. We d...
Source: Case Reports in Neurology - May 27, 2021 Category: Neurology Source Type: research