Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations
CONCLUSION: Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis.PMID:37524447 | DOI:10.1136/bjo-2023-323596
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Xiaotong Han Siyu Pan Jialin Liu Xiaohu Ding Xingyan Lin Decai Wang Zhi Xie Changqing Zeng Fan Liu Mingguang He Xiangtian Zhou Tianzi Liu Lixia Luo Yizhi Liu Source Type: research

Handheld chromatic pupillometry can reliably detect functional glaucomatous damage in eyes with high myopia
CONCLUSION: PLRs to ramping-up light stimuli are unaltered in highly myopic eyes without other diagnosed ocular conditions. Conversely, HCP can distinguish glaucomatous functional loss in eyes with HM and can be a useful tool to detect/confirm the presence of glaucoma in patients with HM.PMID:37524446 | DOI:10.1136/bjo-2023-323878
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Maxwell Toan Finkelstein Monisha Esther Nongpiur Rahat Husain Shamira Perera Mani Baskaran Tina T Wong Tin Aung Dan Milea Raymond P Najjar Source Type: research

Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations
CONCLUSION: Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis.PMID:37524447 | DOI:10.1136/bjo-2023-323596
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Xiaotong Han Siyu Pan Jialin Liu Xiaohu Ding Xingyan Lin Decai Wang Zhi Xie Changqing Zeng Fan Liu Mingguang He Xiangtian Zhou Tianzi Liu Lixia Luo Yizhi Liu Source Type: research

Handheld chromatic pupillometry can reliably detect functional glaucomatous damage in eyes with high myopia
CONCLUSION: PLRs to ramping-up light stimuli are unaltered in highly myopic eyes without other diagnosed ocular conditions. Conversely, HCP can distinguish glaucomatous functional loss in eyes with HM and can be a useful tool to detect/confirm the presence of glaucoma in patients with HM.PMID:37524446 | DOI:10.1136/bjo-2023-323878
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Maxwell Toan Finkelstein Monisha Esther Nongpiur Rahat Husain Shamira Perera Mani Baskaran Tina T Wong Tin Aung Dan Milea Raymond P Najjar Source Type: research

Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations
CONCLUSION: Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis.PMID:37524447 | DOI:10.1136/bjo-2023-323596
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Xiaotong Han Siyu Pan Jialin Liu Xiaohu Ding Xingyan Lin Decai Wang Zhi Xie Changqing Zeng Fan Liu Mingguang He Xiangtian Zhou Tianzi Liu Lixia Luo Yizhi Liu Source Type: research

Handheld chromatic pupillometry can reliably detect functional glaucomatous damage in eyes with high myopia
CONCLUSION: PLRs to ramping-up light stimuli are unaltered in highly myopic eyes without other diagnosed ocular conditions. Conversely, HCP can distinguish glaucomatous functional loss in eyes with HM and can be a useful tool to detect/confirm the presence of glaucoma in patients with HM.PMID:37524446 | DOI:10.1136/bjo-2023-323878
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Maxwell Toan Finkelstein Monisha Esther Nongpiur Rahat Husain Shamira Perera Mani Baskaran Tina T Wong Tin Aung Dan Milea Raymond P Najjar Source Type: research

Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations
CONCLUSION: Our study identified two population-specific novel loci for AL, expanding our understanding of the genetic basis of AL and providing evidence for a role of the nervous system and glucose metabolism in myopia pathogenesis.PMID:37524447 | DOI:10.1136/bjo-2023-323596
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Xiaotong Han Siyu Pan Jialin Liu Xiaohu Ding Xingyan Lin Decai Wang Zhi Xie Changqing Zeng Fan Liu Mingguang He Xiangtian Zhou Tianzi Liu Lixia Luo Yizhi Liu Source Type: research

Handheld chromatic pupillometry can reliably detect functional glaucomatous damage in eyes with high myopia
CONCLUSION: PLRs to ramping-up light stimuli are unaltered in highly myopic eyes without other diagnosed ocular conditions. Conversely, HCP can distinguish glaucomatous functional loss in eyes with HM and can be a useful tool to detect/confirm the presence of glaucoma in patients with HM.PMID:37524446 | DOI:10.1136/bjo-2023-323878
Source: The British Journal of Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Maxwell Toan Finkelstein Monisha Esther Nongpiur Rahat Husain Shamira Perera Mani Baskaran Tina T Wong Tin Aung Dan Milea Raymond P Najjar Source Type: research

Four-year visual outcomes and optical quality of SMILE and implantable collamer lens V4c (EVO-ICL) implantation for high myopia: a retrospective study
To compare the 4-year visual outcomes of implantable collamer lens V4c (EVO-ICL) implantation and small incision lenticule extraction (SMILE) for high myopia and astigmatism.
Source: BMC Ophthalmology - July 31, 2023 Category: Opthalmology Authors: Wuqiang Luo, Aruma Aruma, Meiyan Li, Jing Wang, Jing Xie, Xin Xiao, Yang Shen, Lingling Niu, Xiaoying Wang and Xingtao Zhou Tags: Research Source Type: research

Effect of Peripapillary Atrophy to Diagnose Glaucoma in High Myopia
Conditions:   Myopia;   Refractive Errors;   Eye Diseases;   Glaucoma, Primary Open Angle;   Peripapillary Atrophy Intervention:   Diagnostic Test: OCT imaging Sponsor:   Zhongshan Ophthalmic Center, Sun Yat-sen University Not yet recruiting
Source: ClinicalTrials.gov - July 28, 2023 Category: Research Source Type: clinical trials

Eyes and the heart: what a clinician should know
Heart. 2023 Jul 28:heartjnl-2022-322081. doi: 10.1136/heartjnl-2022-322081. Online ahead of print.ABSTRACTThe eye is prone to various forms of afflictions, either as a manifestation of primary ocular disease or part of systemic disease, including the cardiovascular system. A thorough cardiovascular examination should include a brief ocular assessment. Hypertension and diabetes, for example, would present with retinopathy and dyslipidaemia would present with corneal arcus. Multisystem autoimmune diseases, such as Graves' disease, rheumatoid arthritis and sarcoidosis, would present with proptosis, episcleritis and scleritis,...
Source: Atherosclerosis - July 28, 2023 Category: Cardiology Authors: Jing Yong Ng Essa Zarook Luke Nicholson Oculi-Cordis group Mohammed Yunus Khanji Choudhary Anwar Ahmed Chahal Source Type: research

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