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Pomegranate peel extract polyphenols induced apoptosis in human hepatoma cells by mitochondrial pathway.
This study was aimed to investigate the influence of pomegranate peel polyphenols (PPPs) on the proliferation and apoptosis of HepG2 cells (a kind of human hepatoma cells) and the related mechanism. The inverted fluorescence microscope and the flow cytometer (FCM) were used to test the changes of the cellular morphology, cell cycle, apoptosis, reactive oxygen species (ROS) and mitochondrial transmembrane potential (Δψm). The kit was used to measure the activities of caspase-3/9, and Western Blot was used to detect the expressions of apoptosis-associated proteins including p53, Bcl-2/Bax, Cyt-c and PARP. The results showe...
Source: Food and Chemical Toxicology - April 23, 2016 Category: Food Science Authors: Song B, Li J, Li J Tags: Food Chem Toxicol Source Type: research
Regulation of urinary crystal inhibiting proteins and inflammatory genes by lemon peel extract and formulated citrus bioflavonoids on ethylene glycol induced urolithic rats.
The objective of this study is to check the regulation of crystal matrix proteins and inflammatory mediators by citrus bioflavonoids (CB) and Lemon peel (LP) extract in hyperoxaluric rats. The animals were divided into six groups with 6 animals each. Group 1: Control, Group 2: Urolithic (Ethylene glycol (EG)-0.75%); Group 3& 5: Preventive study (EG + CB (20 mg/kg body weight) and LP (100 mg/kg body weight) extract administration from 0th-7th week) respectively; Group 4 & 6: Curative study (EG + CB and LP extract administration from 4th-7th week) respectively by oral administration. Urinary lithogenic factors ...
Source: Food and Chemical Toxicology - May 26, 2016 Category: Food Science Authors: Sridharan B, Mehra Y, Ganesh RN, Pragasam V Tags: Food Chem Toxicol Source Type: research
Protective effects of rambutan (Nephelium lappaceum) peel phenolics on H2O2-induced oxidative damages in HepG2 cells and d-galactose-induced aging mice.
Abstract
Rambutan peel phenolic (RPP) extracts were prepared via dynamic separation with macroporous resin. The total phenolic content and individual phenolics in RPP were determined. Results showed that the total phenolic content of RPP was 877.11 mg gallic acid equivalents (GAE)/g extract. The content of geranin (122.18 mg/g extract) was the highest among those of the 39 identified phenolic compounds. RPP protected against oxidative stress in H2O2-induced HepG2 cells in a dose-response manner. The inhibitory effects of RPP on cell apoptosis might be related to its inhibitory effects on the generation of intrac...
Source: Food and Chemical Toxicology - January 26, 2017 Category: Food Science Authors: Zhuang Y, Ma Q, Guo Y, Sun L Tags: Food Chem Toxicol Source Type: research
Evidence of insulin-dependent signalling mechanisms produced by Citrus sinensis (L.) Osbeck fruit peel in an insulin resistant diabetic animal model.
Abstract
Citrus sinensis (L.) Osbeck is extensively cultivated worldwide and one of the most consumed fruits in the world. We evaluated the therapeutic properties of the methanol extract from Citrus sinensis fruit peel (CSMe) in high-fat diet-fed streptozotocin-induced insulin-resistant diabetic rats. Body weight, food intake, and water consumption were analysed. Biochemical and molecular biologic indices, and the expression of insulin receptor-induced signalling molecules were assessed to identify possible mechanisms. In addition, we conducted histology of pancreatic and adipose tissues. UHPLC-MS/MS analysis show...
Source: Food and Chemical Toxicology - March 31, 2018 Category: Food Science Authors: Sathiyabama RG, Gopalsamy RG, Denadai M, Sridharan G, Gnanasekaran J, Ponnusamy S, Siqueira Quintans JS, Narain N, Cuevas LE, Coutinho HDM, Ramos AGB, Quintans-Júnior LJ, Gurgel RQ Tags: Food Chem Toxicol Source Type: research
Effects of rambutan (Nephelium lappaceum) peel phenolics and Leu-Ser-Gly-Tyr-Gly-Pro on hairless mice skin photoaging induced by ultraviolet irradiation.
Abstract
Rambutan peel phenolics (RPP) have high antioxidant and anti-inflammatory activities. Leu-Ser-Gly-Tyr-Gly-Pro (LSGYGP) possesses good radical scavenging activity and matrix metalloproteinase (MMPs) inhibitory ability. These underlying mechanisms indicated that RPP and LSGYGP may be used for antiphotoaging. Few data on the effects of RPP and LSGYGP on in vivo photoaging are available. We evaluated the effects of RPP and/or LSGYGP on ultraviolet (UV)-induced hairless mice skin photoaging. In particular, we analyzed the additive effect of RPP and LSGYGP. The biochemical indices of mice skin, including compos...
Source: Food and Chemical Toxicology - April 18, 2019 Category: Food Science Authors: Xiao J, Liu B, Zhuang Y Tags: Food Chem Toxicol Source Type: research
Preparation and characterization of raw and carbon from banana peel by microwave activation: Application in citric acid adsorption
Publication date: Available online 2 September 2015 Source:Journal of Environmental Chemical Engineering Author(s): D. Pranav, Sachin A. Mandavgane Microwave-assisted char (MBPC) was synthesized from raw banana peel (RBP) and the potential of these adsorbents to remove CA from aqueous solution is studied. The adsorbents were characterized by elemental analysis, BET surface area, point of zero charge, surface pH, surface charges, SEM, FTIR, and TGA/DTG. Following microwave treatment, the surface area of MBPC increased to 22.37m2/g (from 0.65m2/g) which is 34.41 times more. The adsorption properties of MBPC and RBP were ...
Source: Journal of Environmental Chemical Engineering - September 4, 2015 Category: Chemistry Source Type: research
Glucose production from potato peel waste under microwave irradiation
Publication date: June 2016 Source:Journal of Molecular Catalysis A: Chemical, Volume 417 Author(s): Vijay Bhooshan Kumar, Indra Neel Pulidindi, Aharon Gedanken Potato starch was chemically hydrolyzed to glucose using silicotungstic acid (H4SiW12O40·nH2O, HSiW) as catalyst under microwave irradiation in a short duration (5min). Potato starch was completely converted to glucose, levulinic acid and formic acid. The methodology was further used for the conversion of potato peel waste (PPW), a zero value waste to glucose. A glucose yield of 59wt.% was obtained upon the microwave irradiation (15min) of PPW. The combined u...
Source: Journal of Molecular Catalysis A: Chemical - March 20, 2016 Category: Chemistry Source Type: research
Removal of methylene blue dye from artificially contaminated water using citrus limetta peel waste as a very low cost adsorbent
Publication date: September 2016 Source:Journal of the Taiwan Institute of Chemical Engineers, Volume 66 Author(s): Sadia Shakoor, Abu Nasar In the present work, the potential of citrus limetta peel (CLP) as a low cost adsorbent for the removal of Methylene blue (MB) dye was investigated. Batch adsorption studies were conducted to find out how adsorption was affected by various factors like contact time, initial dye concentration, adsorbent dosage, pH and temperature. The experimental data was analysed in the light of Langmuir, Freundlich and Temkin isotherm models. The data was found to be best represented by Langmuir ad...
Source: Journal of the Taiwan Institute of Chemical Engineers - September 18, 2016 Category: Chemistry Source Type: research
Reactions of trimethylaluminium: modelling the chemical degradation of synthetic lubricants.
Abstract
In investigating and seeking to mimic the reactivity of trimethylaluminium (TMA) with synthetic, ester-based luricating oils the reaction of methyl propionate 1 was explored with 1, 2 and 3 eq. the organoaluminium reagent. Spectroscopic analysis points to the formation of the adduct 1(TMA) accompanied only by the low level 1:1 production of Me2AlOCEtMe2 2 and Me2AlOMe 3 when an equimolar amount of TMA is applied. The deployment of excess TMA favours reaction to give 2 and 3 over 1(TMA) adduct formation and spectroscopy reveals that in hydrocarbon solution substitution product 2 traps unreacted TMA to yiel...
Source: Chemistry - October 27, 2016 Category: Chemistry Authors: Wheatley A, Slaughter J, Peel A Tags: Chemistry Source Type: research
Microwave-assisted synthesis of glycerol carbonate by the transesterification of glycerol with dimethyl carbonate using Musa acuminata peel ash catalyst
Publication date: Available online 27 June 2019Source: Journal of the Taiwan Institute of Chemical EngineersAuthor(s): Bishwajit Changmai, Ikbal B. Laskar, Lalthazuala RokhumAbstractMusa acuminata peel ash (MAPA), a biowaste-derived solid base catalyst is investigated for the transesterification of glycerol with dimethyl carbonate (DMC) to glycerol carbonate (GC), a potential fuel additive, under microwave irradiation. High basicity, high surface area and mesoporous nature of the catalyst effectively promote the conversion of glycerol to GC. Moreover, the catalyst being a biowaste is abundantly available, cheap, biodegrada...
Source: Journal of the Taiwan Institute of Chemical Engineers - June 27, 2019 Category: Chemistry Source Type: research
Comparisons of process intensifying methods in the extraction of pectin from pomelo peel
Publication date: Available online 5 July 2019Source: Chemical Engineering and Processing - Process IntensificationAuthor(s): Shan Qin Liew, Wen Hui Teoh, Rozita Yusoff, Gek Cheng NgohAbstractThe extraction of pectin from pomelo peel using conventional heating extractive method with acid (CE), sequential ultrasound-microwave assisted technique (UMAE) and dynamic subcritical water extractive technique (SWE) were compared. The physicochemical properties of pectin extracted using the three different techniques were found to be of good quality. The viscosity of the extracted pectin was found to be ˜0.01 Pa.s while exhibitin...
Source: Chemical Engineering and Processing: Process Intensification - July 6, 2019 Category: Chemistry Source Type: research
Green Synthesis of TiO2 NPs/Pristine Pomegranate Peel Extract Nanocomposite and its Antimicrobial Activity for Water Disinfection
In this study pristine pomegranate peel extract (PPP) was used for green synthesis of titanium dioxide nanoparticles (TiO2 NPs) and formation of a nanocomposite (PPP-TiO2). The synthesized nanocomposite were characterized via Scanning Electron Microscope (SEM), Dynamic Light Scattering (DLS), X-ray Powder Diffraction (XRD), and zeta potential (ζ-potential). The DLS results clearly show that TiO2 NPs has peak intensity of 100% with Z-average value of 620 nm, and PDI = 0.178 which affirm the monodisperisty and homogeneity of the synthesized TiO2 NPs. While the DLS result of PPP-TiO2 shows, a bimodal distribution peaks...
Source: Journal of Environmental Chemical Engineering - August 21, 2019 Category: Chemistry Source Type: research
Chemical peeling with trichloroacetic acid and lactic acid for infraorbital dark circles
ConclusionThe combination of trichloroacetic TCA 3.75% and lactic acid 15% showed encouraging results on improving periorbital hyperpigmentation.
Source: Journal of Cosmetic Dermatology - September 1, 2013 Category: Dermatology Authors: Charitomeni Vavouli, Andreas Katsambas, Stamatis Gregoriou, Anca Teodor, Carmen Salavastru, Adina Alexandru, George Kontochristopoulos Tags: Original Contribution Source Type: research
Facial skin rejuvenation: Ablative laser resurfacing, chemical peels, or photodynamic therapy? Facts and controversies
Abstract: Patients and cosmetic surgeons continue to develop innovative devices and techniques in search of the elusive fountain of youth. Our efforts in the past decade can be distilled to three primary approaches: refinement of existing technologies (ablative lasers); refinement of tried-and-true techniques (chemical peeling); and innovative use of new technologies (photorejuvenation). In this contribution, the authors discuss how these three approaches are used to achieve facial skin rejuvenation. Specifically, the authors compare and contrast the clinical benefits and disadvantages of the ablative fractionated and unfr...
Source: Clinics in Dermatology - October 26, 2013 Category: Dermatology Authors: Khaled M. Hassan, Anthony V. Benedetto Source Type: research
Chemical peels in melasma: A review with consensus recommendations by Indian pigmentary expert group
Rashmi Sarkar, Shehnaz Arsiwala, Neha Dubey, Sidharth Sonthalia, Anupam Das, Latika Arya, Narendra Gokhale, RG Torsekar, VK Somani, Imran Majid, Kiran Godse, G Ravichandran, Mohan Singh, Sanjeev Aurangabadkar, T Salim, Swapnil Shah, Surabhi SinhaIndian Journal of Dermatology 2017 62(6):470-476
Melasma is a notorious dermatosis, often resistant to treatment. Chemical peeling constitutes an acceptable option of management of melasma (of any type and duration). In this article, as a group of experts from Pigmentary Disorders Society (PDS) in collaboration with South Asian Pigmentary Forum (SPF), we have tried to elaborate th...
Source: Indian Journal of Dermatology - November 24, 2017 Category: Dermatology Authors: Rashmi Sarkar Shehnaz Arsiwala Neha Dubey Sidharth Sonthalia Anupam Das Latika Arya Narendra Gokhale RG Torsekar VK Somani Imran Majid Kiran Godse G Ravichandran Mohan Singh Sanjeev Aurangabadkar T Salim Swapnil Shah Surabhi Sinha Source Type: research
