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Chemical peels in active acne and acne scars
Chemical peeling is a widely used procedure in the management of acne and acne scars. It causes controlled destruction of a part of or the entire epidermis, with or without the dermis, leading to exfoliation and removal of superficial lesions, followed by regeneration of new epidermal and dermal tissues. The most frequently used peeling agents are salicylic acid, glycolic acid, pyruvic acid, lactic acid, mandelic acid, Jessner solution, trichloroacetic acid, and phenol. The appropriate peel is chosen based on the patient ’s skin type, acne activity, and type of acne scars.
Source: Clinics in Dermatology - February 28, 2017 Category: Dermatology Authors: Georgios Kontochristopoulos, Eftychia Platsidaki Source Type: research

Combining in-office chemical peel procedures with topical therapy of a comprehensive pigmentation control product for multiethnic subjects with moderate to severe facial hyperpigmentation
Dyschromia is one of the primary complaints for patients with skin of color. Treatments need to achieve a balance between tolerability and efficacy to address existing hyperpigmentation without causing additional damage that could trigger post-inflammatory hyperpigmentation (PIH). An open-label, single-center study was conducted to assess the efficacy of a novel comprehensive pigmentation control serum (LYT2) combined with a series of three very superficial chemical peels (VP) in skin of color subjects.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research

Radio Peel—Synergism Between Nano-fractional Radiofrequency and 20% Trichloroacetic Acid Chemical Peeling
CONCLUSION FRF→TCA had the best synergistic effect on skin rejuvenation compared with FRF or TCA20% alone and TCA→FRF.
Source: Dermatologic Surgery - April 27, 2019 Category: Dermatology Tags: Original Article Source Type: research

Depth of injury of Hetter's phenol-croton oil chemical peel formula using 2 different emulsifying agents
To the Editor: Deep  chemical peels consist of the application of a mixture of phenol, croton oil, water, and, historically, a handwash soap containing triclosan and sodium C14-16 olefin sulfonate as the emulsifying agent (Septisol [SEP], Steris Corp, Mentor, OH).1 Because of the US Food and Drug Administration's fina l rule on hand sanitizers,2 which prohibits the use of triclosan, SEP was discontinued. The classic Baker-Gordon's formula3 (2.1% croton oil/49.3% phenol) and Hetter's standardized formulas (0.1%-1.6% croton oil/35% phenol) contained 5% SEP, which generated a very unstable emulsion1 that spontaneou sly sepa...
Source: Journal of the American Academy of Dermatology - March 1, 2020 Category: Dermatology Authors: Aline da Silva Justo, Bruna Mikulis Lemes, Bruna Nunes, Kevin Alves Antunes, Bruna Carletto, Adriana Yuriko Koga, Leandro Cavalcante Lipinski, Mario Rodrigues Montemor Netto, Eduardo Bauml Campagnoli, Fl ávio Luís Beltrame, Carlos Gustavo Wambier Tags: Letter Source Type: research

Chemical peeling in ethnic skin: an update
This article aims to review the background, classification, various preparations, indications, patient assessment and complications of using chemical peels in ethnic skin.
Source: British Journal of Dermatology - October 4, 2013 Category: Dermatology Authors: A. Salam, O.E. Dadzie, H. Galadari Tags: Review Article Source Type: research

A Study Comparing the Efficacy of Monopolar Radiofrequency and Glycolic Acid Peels in Facial Rejuvenation of Aging Skin Using Histopathology and Ultrabiomicroscopic Sonography (UBM) - An Evidence Based Study.
CONCLUSION: Radiofrequency and chemical peels showed equal efficacy in the treatment of facial rejuvenation. PMID: 27131351 [PubMed - as supplied by publisher]
Source: Acta Medica: Hradec Kralove - May 2, 2016 Category: Journals (General) Tags: Acta Medica (Hradec Kralove) Source Type: research

Combination of In-Office Chemical Peels With a Topical Comprehensive Pigmentation Control Product in Skin of Color Subjects With Facial Hyperpigmentation.
Authors: Downie J, Schneider K, Goberdhan L, Makino ET, Mehta RC Abstract <p>Dyschromia is one of the primary complaints for patients with skin of color. Treatments need to achieve a balance between tolerability and efficacy to address existing hyperpigmentation without causing additional damage that could trigger post-inflammatory hyperpigmentation (PIH). An open-label, single-center study was conducted to assess the efficacy of a novel comprehensive pigmentation control serum (LYT2) combined with a series of three very superficial chemical peels (VP) in skin of color subjects. Seventeen female and male subj...
Source: Journal of Drugs in Dermatology - April 15, 2017 Category: Dermatology Tags: J Drugs Dermatol Source Type: research

Effective treatment of disseminated superficial actinic porokeratosis with chemical peels - customary treatment for a rare disease.
We report a series of five female patients with history of DSAP that were successfully treated with chemical peels. All patients suffered from the disease for 14.4 years on average and all were refractory to at least two therapeutic options, mostly imiquimod and topical tretinoin. Patients were treated with glycolic acid 50% and salicylic acid 25% in a two-layer-technique. After a mean of three cycles every six weeks a clear reduction in lesion was assessed by physicians. Patients were highly satisfied with outcome and rare occurrence of side effects as assessed by TSQM questionnaire. Chemical peels are safe and well toler...
Source: Journal of Dermatological Treatment - April 27, 2019 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Characterization of the Activity of Croton tiglium Oil in Hetter's Very Heavy Phenol–Croton Oil Chemical Peels
CONCLUSION Coagulative necrosis of the epidermis, superficial fibroblasts, and vasculature can be attributed to the action of phenol. Phorbol esters on CO could be responsible for the dense deep acute inflammation and the distinctive neocollagenesis.
Source: Dermatologic Surgery - July 1, 2021 Category: Dermatology Tags: Original Article Source Type: research

Laser and Face Peel Procedures in Non-Caucasians
This article discusses the most frequently used lasers and chemical peels used to address these problems.
Source: Facial Plastic Surgery Clinics of North America - June 12, 2014 Category: Cosmetic Surgery Authors: Mark J. Been, Devinder S. Mangat Source Type: research

Randomized controlled trial comparing 35% trichloroacetic acid peel and 5 ‐aminolevulinic acid photodynamic therapy for the treatment of multiple actinic keratosis
ConclusionsALA PDT provided better clinical results than TCA in the treatment of patients with extensive field cancerisation and multiple AK.This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - December 22, 2016 Category: Dermatology Authors: G. Holzer, A. Pinkowicz, S. Radakovic, J.B. Schmidt, A. Tanew Tags: Original Article Source Type: research

Randomized controlled trial comparing 35% trichloroacetic acid peel and 5 ‐aminolaevulinic acid photodynamic therapy for treating multiple actinic keratosis
ConclusionsALA PDT provided better clinical results than TCA in the treatment of patients with extensive field cancerization and multiple AKs.
Source: British Journal of Dermatology - April 5, 2017 Category: Dermatology Authors: G. Holzer, A. Pinkowicz, S. Radakovic, J.B. Schmidt, A. Tanew Tags: Clinical Trials Source Type: research

Advanced, physician-strength retinol peel improves the appearance of fine lines, wrinkles, skin firmness, and overall complexion brightness
Background: As noninvasive, topical cosmetic procedures increase in popularity, the ability to provide beneficial results is increasingly in demand. Physician-strength chemical peels are consistently the third most common cosmetic procedure next to neurotoxin and soft-tissue filler injections. Among physicians, retinol continues to be a proven ingredient for adjunctive care of conditions such as acne and/or photodamage due to its ability to enhance exfoliation, increase epidermal thickness and reduce matrix metalloproteinase (MMP) activity (collagenase) while increasing collagen.
Source: Journal of the American Academy of Dermatology - May 31, 2017 Category: Dermatology Source Type: research

Chemical Peels and Fractional Laser on IGF-1 Levels in Skin
Condition:   IGF-1 Level Intervention:   Device: Fractional Laser and Chemical Peel Sponsor:   Massachusetts General Hospital Not yet recruiting
Source: ClinicalTrials.gov - December 13, 2018 Category: Research Source Type: clinical trials