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New book provides practical guidance for women (and men) to rebalance our lifestyles and build Cognitive Reserve
On one of our “walk and talks” around the lush trails of Rock Creek Park in DC surrounded by bikers, runners, cars and the occasional deer, Wendy and Lisa talked about aging. Wendy’s mother, who had her children in her early 20s, was still joining the family’s grueling summer hikes with her children and nine grandchildren well into her 60s. Wendy mused about how much older she would be when their kids could have their own kids. It dawned on her that her health was not just a here and now issue, but an investment in that future. We agreed to help each other cultivate the habits and make time to build strength as wel...
Source: SharpBrains - May 17, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning book Cognitive-impairment cognitive-reserve dementia healthy-aging Lifelong Neuroplasticity physical-health Rebalance Source Type: blogs

When a Loved One with Alzheimer's Doesn't Recognize You
Photo credit D Mason Watching a loved one move through the stages of Alzheimer's disease (AD) can be one of life's toughest and most heartbreaking challenges. If we had to list examples of emotions by the distress they cause us, at the top of the list would be watching someone we love experience physical and mental pain that we cannot relieve. For many caregivers, next on the list at least for many caregivers, would be having to live with the fact that a loved one no longer recognizes us for who we are.  When my family members were residents of a care facility, I asked one of the nurses at the nursing home if my moth...
Source: Minding Our Elders - May 16, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

The Future Of Vision And Eye Care
3D printed digital contact lenses, bionic eye implants, augmented reality: the future of vision and eye care is full of science fiction-sounding innovations. Here is where digital health will take ophthalmology in the future! More than 80 percent of perception comes through vision Researchers estimate that 80-85 percent of our perception, learning, cognition, and activities are mediated through vision. Compared to that, our hearing only processes 11 percent of information, while smell 3.5 percent, touch 1.5 percent and taste 1 percent. Don’t you think that’s possible? Renowned scholars, L.D. Ros...
Source: The Medical Futurist - May 10, 2022 Category: Information Technology Authors: berci.mesko Tags: Augmented Reality Cyborgization 3d printing AI diabetes digital digital health future guide Healthcare Innovation Personalized medicine technology vision eye care ophthalmology Source Type: blogs

The Reckoning: What Happens to Digital Health After COVID?
By JEFF GOLDSMITH and ERIC LARSEN It has been a rough year so far for digital health. After an astonishing $45 billion poured into new digital health companies in 2020 and 2021, and an early 2021 peak in market valuations of publicly-traded digital health providers, valuations and multiples have collapsed. Once high-flying Teladoc, which traded at an eye-watering 42x revenues and commanded a $45 billion market capitalization, is now trading around 2.7X at about $5.7 billion. AmWell, the next largest telehealth player, has seen its stock drop more 90% from its high. Nor is the evaporation in market value is co...
Source: The Health Care Blog - May 9, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Tech digital health Digital health investing Eric Larsen Healthcare bubble Jeff Goldsmith Source Type: blogs

Sheldon Krimsky
, who supervised my master ' s thesis at Tufts, has died at age 80.His NYT obituary is here, if you haven ' t used up your free reads. His work is highly relevant to a discussion we ' ve been having here.  Shelly was a member of the National Academy of Sciences, and he was a critic of science. His life ' s work was to expose corruption in science, and warn of the negative effects of technology. Sometimes he went a bit overboard, in my view, particularly with respect to gene editing. He was much more alarmed by it than I think was really called for, but that ' s okay. We need to think about worst case scenarios. A...
Source: Stayin' Alive - May 6, 2022 Category: American Health Source Type: blogs

75 You Are Worthy Quotes to Empower and Give You Self-Confidence
You are worthy of the life you dream about. This is not always easy to see though (especially, in my experience, when you’ve just had a setback or two). It’s easy to get down on yourself. To be dragged down by your thoughts or the discouraging words of others. So in this post I’d like to give you a boost of motivation and a belief in yourself and your goals and dreams by sharing the most powerful you are worthy quotes and sayings from the last 2500 years. I hope you’ll find something here to help you to keep moving forward and towards what you deep down want out of your life. And if you want more inspirational quo...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - May 2, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs

Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Blind as an ADHD Bat
Ever been so ADHD that you can ’t see what you’re looking for, even when it’s right in front of your face?Given that ADHD has as many flavors as a bag of jelly beans, you might not all relate with ADHD tunnel vision. I, unfortunately, can’t say the same. If I had a jelly bean for every time something I was looking for was found right there in front of me, I could go into business and give Jelly Belly a run for their money.Today, the missing item was my iPhone. I got up from the table, left the kitchen, then wondered where my iPhone had gone. I went downstairs and searched for it. My daughter called it. I visite...
Source: The Splintered Mind by Douglas Cootey - April 28, 2022 Category: Psychiatry Tags: ADHD Goodreads Source Type: blogs

3 Tips to Start the  Process of Writing a Book
“I have a book within me just waiting to be born.” “I keep notes of these phrases that come to me.” “I’ve tried over and over and haven't been able to write it.” As a book-writing coach, I hear these types of comments a lot. There are so many talented, smart individuals who have a book living inside them, but for myriad reasons — time management, writer's block, fear of failure — they have trouble getting it onto the page. The process of writing a book is complex, time-intensive, and filled with obstacles, some mental and some physical. Every journey starts differently, yet the path ...
Source: PickTheBrain | Motivation and Self Improvement - April 28, 2022 Category: Consumer Health News Authors: Erin Falconer Tags: career confidence creativity featured productivity tips success writing tips how to write a book Source Type: blogs

Calorie Restriction and mTOR Inhibition are Additive in Slowing Muscle Loss with Age
It is intriguing to see that calorie restriction and mTOR inhibition are additive when it comes to slowing the age-related loss of muscle mass and strength, the path to sarcopenia. Both interventions are thought to influence long-term health largely through upregulation of autophagy, but calorie restriction produces very broad, sweeping changes in metabolism. The downstream changes due to mTOR inhibition only touch on a fraction of those. Thus this result may in time lead to a better understanding of which mechanisms are important in the way in which the operation of metabolism determines the pace of aging. Still, we know ...
Source: Fight Aging! - April 26, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How is RCA angina different from LAD angina ?
William Heberden first introduced the term angina to the medical community in 1778. His descriptions became immortal. Still, no one would ever know what was the angina-related artery, Heberden was alluding to. Now, some jobless cardiologist is asking this question after 200 years. How is angina from the LAD system differ from the RCA  system? or let me put it another way, How does angina of anterior circulation (LAD) differ from posterior circulation (RCA/LCX)? Though there is distinct hemodynamic profiling of RCAvs LAD ACS, surprisingly, cardiology literature does not answer the chest pain aspect of it. One rare stud...
Source: Dr.S.Venkatesan MD - April 26, 2022 Category: Cardiology Authors: dr s venkatesan Tags: acute coroanry syndrome angina cardiac embryology Cardiology - Clinical Cardiology -Mechnisms of disease Clinical cardiology Source Type: blogs

CollabCare and Hucu.ai Partner to Improve Communication for Older Adults and Families
Digital health solutions have helped to democratize access for underserved individuals and communities. With both increasing maturity and adoption across generations, the ability for these technologies to address the challenges faced by older adults ...
Source: Medgadget - April 25, 2022 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Geriatrics Rehab CollabCare hucu.ai Source Type: blogs

Empowering Trainees to be Leaders and Change Agents
We described several wellness initiatives that were done at individual campuses. The University of Illinois where I attend, we had a wellness committee that we formed led by students. We were able to partner with local companies to bring in more healthy food options. We were able to set up a counseling center dedicated specifically towards medical trainees. Joe Geraghty: And so that’s at the institutional level, but then in our local community, we had several letters from places like the University of Chicago. We had a medical student who wrote about how they were developing kind of like easy to digest infograp...
Source: Academic Medicine Blog - April 25, 2022 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Annual Call for Trainee-Authored Letters to the Editor ATLAS Trainee Perspective leadership medical education scholarship medical students residents scholarly publishing trainee engagement Source Type: blogs

ADHD: Here Are Five Steps I Use to Rein In My Focus
A lack of focus is the one common trait that all adults with ADHD seem to have, but focus isn’t as elusive as you might fear.The other day, a friend texted me out of the blue. He wanted a list of some of the things that I do to maintain focus. Initially, I panicked. I’ve been chronically ill since getting COVID–19 last October. I haven’t blogged in four months, so my ADHD advice muscles were all out of shape. Fortunately for my friend, I haven’t met a topic yet that I didn’t have an opinion on, so I worked up my courage and sent a list to him.Finding focus is a complicated issue foradult...
Source: The Splintered Mind by Douglas Cootey - April 23, 2022 Category: Psychiatry Tags: ADHD Goodreads Source Type: blogs

Chest pain, a ‘normal’ ECG, a ' normal trop ' , and low HEART and EDACS scores: Discharge home? Stress test? Many errors here.
Written by Jesse McLaren, with comments from Smith and GrauerA 60 year old presented with three weeks of intermittent non-exertional chest pain without associated symptoms. ECG was labeled ‘normal’ by the computer (confirmed by the overreading cardiologist) and the high-sensitivity Troponin I was normal at a value of 11 ng/L (Abbott Alinity assay, where normal is<26 in males,<16 in females; this assay is nearly identical to the Abbott Architect high sensitivity assay). So the patient was low risk according to HEART and EDACS scores. Should this patient be discharged home? How about a stress test?   ...
Source: Dr. Smith's ECG Blog - April 22, 2022 Category: Cardiology Authors: Jesse McLaren Source Type: blogs