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It ' s Time to Start Preparing Against Flu, RSV & COVID-19
FRIDAY, Sept. 15, 2023 – Kids are back in school and it’s time to think about viruses, for both yourself and them. It could be an early flu season in the United States, if what happened in the Southern Hemisphere offers any insight, according to...
Source: Drugs.com - Daily MedNews - September 15, 2023 Category: General Medicine Source Type: news

Concurrent determination of cyanide and thiocyanate in human and swine antemortem and postmortem blood by high-performance liquid chromatography-tandem mass spectrometry
Anal Bioanal Chem. 2023 Sep 15. doi: 10.1007/s00216-023-04939-6. Online ahead of print.ABSTRACTCyanide (in the form of cyanide anion (CN-) or hydrogen cyanide (HCN), inclusively represented as CN) can be a rapidly acting and deadly poison, but it is also a common chemical component of a variety of natural and anthropogenic substances. The main mechanism of acute CN toxicity is based on blocking terminal electron transfer by inhibiting cytochrome c oxidase, resulting in cellular hypoxia, cytotoxic anoxia, and potential death. Due to the well-established link between blood CN concentrations and the manifestation of symptoms,...
Source: Analytical and Bioanalytical Chemistry - September 15, 2023 Category: Chemistry Authors: Abdullah H Alluhayb Carter Severance Tara Hendry-Hofer Vikhyat S Bebarta Brian A Logue Source Type: research

Evaluating the potential of biodegradation of swine manure through rotary drum composting utilizing different bulking agents
In this study, the potential of three different bulking agents (sawdust, dry leaves, and rice straw) for the biodegradation of piggery waste was evaluated through rotary drum composting (RDC). Following the composting time of 20 days, evaluations of macro and micronutrient concentrations and the C/N ratio revealed stable, matured compost that could be used in farming. However, the saw dust amended RDC (RDC1) outperformed among the studied trails; the total nitrogen content of 1.54%, total phosphorus of 7.68 g/kg, and total potassium of 23.45 g/kg demonstrated the bioproduct produced through RDC1 resulted in superior-qualit...
Source: Bioresource Technology - September 15, 2023 Category: Biotechnology Authors: C Lalthlansanga Suryateja Pottipati Nava Sreeram Meesala Ajay S Kalamdhad Bijayananda Mohanty Source Type: research

Concurrent determination of cyanide and thiocyanate in human and swine antemortem and postmortem blood by high-performance liquid chromatography-tandem mass spectrometry
Anal Bioanal Chem. 2023 Sep 15. doi: 10.1007/s00216-023-04939-6. Online ahead of print.ABSTRACTCyanide (in the form of cyanide anion (CN-) or hydrogen cyanide (HCN), inclusively represented as CN) can be a rapidly acting and deadly poison, but it is also a common chemical component of a variety of natural and anthropogenic substances. The main mechanism of acute CN toxicity is based on blocking terminal electron transfer by inhibiting cytochrome c oxidase, resulting in cellular hypoxia, cytotoxic anoxia, and potential death. Due to the well-established link between blood CN concentrations and the manifestation of symptoms,...
Source: Analytical and Bioanalytical Chemistry - September 15, 2023 Category: Chemistry Authors: Abdullah H Alluhayb Carter Severance Tara Hendry-Hofer Vikhyat S Bebarta Brian A Logue Source Type: research

Pulsed field ablation for pulmonary vein isolation: Preclinical safety and effectiveness of a novel hexaspline ablation catheter
ConclusionIn the chronic canine study, PFA-based PVI were safe and effective with demonstrable sparing of nerves and venous tissue. Compared with RFA, there was also good evidence for safety of PFA, avoiding PV stenosis and esophageal injury. This preclinical study provided the scientific basis for the first-in-human endocardial PFA studies.
Source: Journal of Cardiovascular Electrophysiology - September 15, 2023 Category: Cardiology Authors: Fengyuan Yu, Xiaonan Dong, Lei Ding, Vivek Reddy, Min Tang Tags: ORIGINAL ARTICLE Source Type: research

Protocol of the process evaluation of cluster randomised control trial for estimating the effectiveness and cost-effectiveness of a complex intervention to increase care home staff influenza vaccination rates compared to usual practice (FluCare)
Influenza (flu) vaccination rates in UK care home staff are extremely low. Less than 40% of staff in care homes are vaccinated for influenza (flu), presenting risks to the health of frail residents and potenti...
Source: Trials - September 15, 2023 Category: General Medicine Authors: Linda Birt, Thando Katangwe-Chigamba, Sion Scott, David J Wright, Adam P. Wagner, Erika Sims, Veronica Bion, Carys Seeley, Faisal Alsaif, Allan Clarke, Alys Griffiths, Liz Jones, Alison Bryant and Amrish Patel Tags: Study protocol Source Type: research

Viruses, Vol. 15, Pages 1925: Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?
hanarat African swine fever (ASF) is a highly contagious and economically devastating disease affecting domestic pigs and wild boar, caused by African swine fever virus (ASFV). Despite being harmless to humans, ASF poses significant challenges to the swine industry, due to sudden losses and trade restrictions. The ongoing COVID-19 pandemic has spurred an unparalleled global research effort, yielding remarkable advancements across scientific disciplines. In this review, we explore the potential technological spillover from COVID-19 research into ASF. Specifically, we assess the applicability of the diagnostic tools, vac...
Source: Viruses - September 15, 2023 Category: Virology Authors: Danaya Pakotiprapha Sakonwan Kuhaudomlarp Ruchanok Tinikul Sittinan Chanarat Tags: Review Source Type: research

Endovascular transmural access to carotid artery perivascular tissues: safety assessment of a novel technique
Conclusion Repeated puncture of the carotid artery to gain access to the perivascular tissues using a novel endovascular transmural approach is safe in a swine model. This represents a novel approach to various tissues in close proximity to the cervical and cranial vasculature.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Kim, W. J., Samarage, H. M., Zarrin, D., Goel, K., Wang, A. C., Johnson, J., Nael, K., Colby, G. P. Tags: New devices New devices and techniques Source Type: research

Genetic diversification patterns in swine influenza A virus (H1N2) in vaccinated and nonvaccinated animals
Influenza A viruses (IAVs) are characterized by having a segmented genome, low proofreading polymerases, and a wide host range. Consequently, IAVs are constantly evolving in nature causing a threat to animal and human health. In 2009 a new human pandemic IAV strain arose in Mexico because of a reassortment between two strains previously circulating in pigs; Eurasian “avian-like” (EA) swine H1N1 and “human-like” H1N2, highlighting the importance of swine as adaptation host of avian to human IAVs. Nowadays, although of limited use, a trivalent vaccine, which include in its formulation H1N1, H3N2, and, H1N2 swine IAV ...
Source: Frontiers in cellular and infection microbiology - September 15, 2023 Category: Microbiology Source Type: research

With the Decongestant SNAFU, the FDA Tries Something New
It’s easy to understand how a medicine like phenylephrine got onto pharmacy shelves in the first place. The common decongestant, used most often as an ingredient in multidrug cold medications like DayQuil and Sudafed PE, was initially designated as “safe and effective” by the Food and Drug Administration (FDA) in 1976, when the agency was newly—and less stringently than today—greenlighting drugs that had been on the market for years before the agency had established any efficacy standards. After a full review of 14 studies (12 unpublished and two published) from pharmaceutical companies—...
Source: TIME: Health - September 14, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized healthscienceclimate Source Type: news

Narcolepsy Diagnosis With Sleep Stage Features Using PSG Recordings
Narcolepsy is a sleep disorder affecting millions of people worldwide and causes serious public health problems. It is hard for doctors to correctly and objectively diagnose narcolepsy. Polysomnography (PSG) recordings, a gold standard for sleep monitoring and quality measurement, can provide abundant and objective cues for the narcolepsy diagnosis. There have been some studies on automatic narcolepsy diagnosis using PSG recordings. However, the sleep stage information, an important cue for narcolepsy diagnosis, has not been fully utilized. For example, some studies have not considered the sleep stage information to diagno...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 14, 2023 Category: Neuroscience Source Type: research

Now the CDC wants to monitor your POOP to track flu outbreaks - after pioneering 'wastewater surveillance' during Covid pandemic
So-called wastewater surveillance was pioneered during the pandemic to track new variants and gave officials early warning of flare-ups in the UK and US.
Source: the Mail online | Health - September 14, 2023 Category: Consumer Health News Source Type: news

Interim Effectiveness Estimates of 2023 Southern Hemisphere Influenza Vaccines in Preventing Influenza-Associated Hospitalizations - REVELAC-i Network, March-July 2023
This report describes flu vaccine effectiveness data from five South American countries during the 2023 Southern Hemisphere flu season.
Source: CDC Morbidity and Mortality Weekly Report - September 14, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news