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RWE-based Treatment Patterns and Outcomes in CIDP
Conditions:   Chronic Inflammatory Demyelinating Polyneuropathy;   Guillain-Barre Syndrome;   Hereditary Amyloidosis Intervention:   Other: No intervention. Retrospective observation only. Sponsors:   RwHealth;   Alnylam Pharmaceuticals;   Northern Care Alliance NHS Foundation Trust Not yet recruiting
Source: ClinicalTrials.gov - July 11, 2023 Category: Research Source Type: clinical trials

Chronic inflammatory demyelinating polyneuropathy after SARS-CoV2 vaccination: update of the literature and patient characterization
AbstractSince the beginning of worldwide vaccination against COVID-19 disease, some reports have revealed a possible relationship between SARS CoV2 vaccination and chronic inflammatory demyelinating polyneuropathy (CIDP). We reviewed the available evidences regarding this topic, adding three new cases to those reported so far, with the purpose to outline the characteristics of these post-vaccinal CIDP. Seventeen subjects were studied. A total of 70.6% of CIDP cases were related to viral vector vaccines, most occurring after the administration of the first dose. CIDPs that occurred after the second dose (17%) were temporall...
Source: Immunologic Research - July 3, 2023 Category: Allergy & Immunology Source Type: research

The diagnostic value of quantitative assessment of MR neurography in chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta-analysis
CONCLUSION: Quantitative MRN has considerable diagnostic value in CIDP patients with accuracy and reliability. FA and CSA can be promising parameters in the future diagnosis of CIDP patients.ADVANCES IN KNOWLEDGE: This is the first meta-analysis of quantitative MRN in the diagnosis of CIDP.We have selected reliable parameters with cut-off value and providednew insights for subsequent diagnosis of CIDP.PMID:37393524 | DOI:10.1259/bjr.20221037
Source: The British Journal of Radiology - July 2, 2023 Category: Radiology Authors: Haofeng Chen Xinyue Huang Yifang Bao Chongbo Zhao Jie Lin Source Type: research

Ultrasound-based radiomic analysis of the peripheral nerves for differentiation between CIDP and POEMS syndrome
CONCLUSION: US-based radiomic analysis has high AUC values in differentiating POEM syndrome from CIDP. Machine-learning algorithms further improved the discriminative ability.PMID:37376758 | DOI:10.1177/02841851231181680
Source: Acta Radiologica - June 28, 2023 Category: Radiology Authors: Jun Hashiba Hajime Yokota Kota Abe Yukari Sekiguchi Shinobu Ikeda Atsuhiko Sugiyama Satoshi Kuwabara Takashi Uno Source Type: research

Anti-neurofascin 155 Antibody-positive Neuropathy in a Human Immunodeficiency Virus-infected Patient
Intern Med. 2023 Jun 28. doi: 10.2169/internalmedicine.1919-23. Online ahead of print.ABSTRACTHuman immunodeficiency virus (HIV)-associated neuropathy is a common complication of HIV infection and has several clinical subtypes. HIV-associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating neuropathy whose clinical features are known to differ from those of CIDP in the HIV-uninfected population. We herein report a case of CIDP in an HIV-infected patient who was finally diagnosed with anti-neurofascin 155 (NF155) antibody-positive neuropathy. The clinical features, including clinical find...
Source: Internal Medicine - June 28, 2023 Category: Internal Medicine Authors: So Okubo Tatsuo Mano Atsushi Sudo Ryoji Goto Satoka Yano Manato Hara Hiroyuki Ishiura Wataru Satake Shintaro Yanagimoto Hidenori Ogata Tatsushi Toda Source Type: research

Ultrasound-based radiomic analysis of the peripheral nerves for differentiation between CIDP and POEMS syndrome
CONCLUSION: US-based radiomic analysis has high AUC values in differentiating POEM syndrome from CIDP. Machine-learning algorithms further improved the discriminative ability.PMID:37376758 | DOI:10.1177/02841851231181680
Source: Acta Radiologica - June 28, 2023 Category: Radiology Authors: Jun Hashiba Hajime Yokota Kota Abe Yukari Sekiguchi Shinobu Ikeda Atsuhiko Sugiyama Satoshi Kuwabara Takashi Uno Source Type: research