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Successful NCBI-NIAID Codeathon Explored VCF Files in Population Genomics
Variant Call Format (VCF) files provide a crucial way to record and share information about genetic variants across samples. NCBI joined forces with the National Institute of Allergy and Infectious Diseases (NIAID) to co-host the VCF Files for Population Genomics Codeathon (July 31 – August 4). The codeathon focused on innovative methods for harnessing VCF … Continue reading Successful NCBI-NIAID Codeathon Explored VCF Files in Population Genomics →
Source: NCBI Insights - September 21, 2023 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Codeathon Genomics SARS-CoV-2 Source Type: news
Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother-child cohort
CONCLUSION: Prenatal dietary exposure to chemicals was associated with risk of allergic rhinitis or wheezing up to age 8 y. A few chemicals were associated with other allergic and respiratory diseases. Larger prospective studies are needed to confirm these findings.PMID:37734145 | DOI:10.1016/j.envint.2023.108195
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Manel Ghozal Manik Kadawathagedara Rosalie Delvert Karine Adel-Patient Muriel Tafflet Isabella Annesi-Maesano Am élie Crépet V éronique Sirot Marie Aline Charles Barbara Heude Blandine de Lauzon-Guillain Source Type: research
Bilastine 0.6% preservative-free eye drops, an effective once-daily treatment to reduce signs and symptoms of allergic conjunctivitis: A pooled analysis of two randomized clinical trials
CONCLUSION: This multi-trial assessment suggests that bilastine 0.6% ophthalmic solution is efficacious for the treatment of the signs and symptoms of allergic conjunctivitis, with a rapid and prolonged duration of action, and has a favorable safety profile. The added convenience of a once-a-day dosing regimen may contribute to patient adherence and improve their quality of life.PMID:37732873 | DOI:10.18176/jiaci.0940
Source: Journal of Investigational Allergology and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: P J Gomes J B Ciolino P Arranz A Gonzalo N Fern ández G Hern ández Source Type: research
Very early onset perinatal constipation: Can it be cow's milk protein allergy?
World J Gastroenterol. 2023 Sep 7;29(33):4920-4926. doi: 10.3748/wjg.v29.i33.4920.ABSTRACTDelayed passage of meconium or constipation during the perinatal period is traditionally regarded as a signal to initiate further work up to evaluate for serious diagnoses such as Hirschsprung's disease (HD), meconium ileus due to Cystic Fibrosis, etc. The diagnosis of HD particularly warrants invasive testing to confirm the diagnosis, such as anorectal manometry or rectal suction biopsy. What if there was another etiology of perinatal constipation, that is far lesser known? Cow's milk protein allergy (CMPA) is often diagnosed in infa...
Source: World Journal of Gastroenterology : WJG - September 21, 2023 Category: Gastroenterology Authors: Rajalakshmy Arakoni Hebat Kamal Sam Xianjun Cheng Source Type: research
European Commission Approves First Tocilizumab Biosimilar European Commission Approves First Tocilizumab Biosimilar
The biosimilar, commercially called Tyenne, is indicated to treat several autoimmune diseases as well as cytokine release syndrome and COVID-19.Medscape Medical News
Source: Medscape Allergy Headlines - September 21, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news
FDA Shoots Down Needle-Free EpiPen Alternative, Requests More Data
(MedPage Today) -- The FDA declined to approve an epinephrine nasal spray (ARS-1, also known as neffy), requesting that an additional premarketing study be conducted, maker ARS Pharmaceuticals announced.
The company is seeking an indication for...
Source: MedPage Today Allergy - September 21, 2023 Category: Allergy & Immunology Source Type: news
Fungal Allergen Sensitization: Prevalence, Risk Factors and Geographic Variation in the United States
Many fungal species are associated with the pathogenesis of allergic disease, yet most epidemiologic studies on IgE-mediated fungal sensitization have only included a few species.
Source: Journal of Allergy and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Kenny Kwong, Matthew Robinson, Adam Sullivan, Stanley Letovsky, Andrew H. Liu, Andre Valcour Source Type: research
Climate change and epigenetic biomarkers in allergic and airway diseases
Human epigenetic variation is associated with both environmental exposures and allergic diseases and can potentially serve as a biomarker connecting climate change with allergy and airway diseases. In this narrative review, we summarize recent human epigenetic studies examining exposure to temperature, precipitation, extreme weather events, and malnutrition to discuss findings as they relate to allergic and airway diseases. Temperature has been the most widely studied exposure, with the studies implicating both short-term and long-term exposure with epigenetic alterations and epigenetic aging.
Source: Journal of Allergy and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Andres Cardenas, Raj Fadadu, Supinda Bunyavanich Source Type: research
Climate change is a health crisis with opportunities for healthcare action: A focus on healthcare providers, patients with asthma and allergic immune diseases, their families and neighbors
We present potential actions individuals can take at the family, neighborhood, community, healthcare system, national and international levels to build climate resilience, to protect their own health and the health and welfare of others.
Source: Journal of Allergy and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Nicholas J. Nassikas, Diane R. Gold Source Type: research
Health-based strategies for overcoming barriers to climate change adaptation and mitigation
Climate change poses an unequivocal threat to the respiratory health of current and future generations. Human activities —largely through the release of greenhouse gases (GHGs)—are driving rising global temperatures. Without a concerted effort to mitigate GHG emissions or adapt to the effects of a changing climate, each increment of warming increases the risk of climate hazards (e.g. heat waves, floods, and drough ts) that that can adversely affect allergy and immunological diseases. For instance, wildfires, which release large quantities of the air pollutant PM2.5, occur with greater intensity, frequency, and duration...
Source: Journal of Allergy and Clinical Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Patrick L. Kinney, Beverly Ge, Vanitha Sampath, Kari Nadeau Source Type: research
Eosinophilic bronchiectasis and therapeutic oportunities
Bronchiectasis is the third most frequent chronic inflammatory disease of the airways after chronic obstructive pulmonary disease (COPD) and asthma. Its diagnosis is established by clinical and radiological criteria based on the abnormal dilation of the bronchial lumen together with a clinical picture compatible with the inflammatory-infectious process causing the destruction of the bronchial wall and producing its dilation. This picture generally consists of a productive cough (often with a purulent component) and a variable number of exacerbations throughout the natural history of the disease 1.
Source: Annals of Allergy, Asthma and Immunology - September 21, 2023 Category: Allergy & Immunology Authors: Grace Oscullo, Jose Daniel Gomez-Olivas, Miguel Ángel Martínez-García Tags: Editorial Source Type: research
Reignite Professional Passion Through Lifestyle Medicine Reignite Professional Passion Through Lifestyle Medicine
In this age of ubiquitous burnout in the health professions, lifestyle medicine fosters clinician healing.Medscape Family Medicine
Source: Medscape Allergy Headlines - September 20, 2023 Category: Allergy & Immunology Tags: Family Medicine/Primary Care Commentary Source Type: news
