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Hopes and Questions raised by Alzheimer ’s drug Leqembi (lecanemab)
The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer’s and a precursor condition, mild cognitive impairment. Medicare has said it will pay for the therapy. Medical centers across the country are scrambling to finalize policies and procedures for providing the medication to patients, possibly by summer’s end or early autumn. It’s a fraught moment, with hope running high for families and other promising therapies such as donanemab on the horizon. Still, medical providers are cautious. “This is an important first step in developing treatments for complex neurodegenerative disea...
Source: SharpBrains - August 17, 2023 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Brain/ Mental Health cognition early-stage Alzheimer’s Eisai FDA lecanemab Leqembi Medicare mild-cognitive-impairment Source Type: blogs

Overcoming terminal cancer: a tale of love and resilience
An excerpt from Mirrors and Windows: Reflections on the Journey in Serious Illness Practice. I’m sitting next to Tony in the surgical intensive care unit doing my best to make out what he’s writing. He’s intubated and I’ve just asked him, “what’s the hardest part of all this?” He writes out, “I just don’t understand Read more… Overcoming terminal cancer: a tale of love and resilience originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 17, 2023 Category: General Medicine Authors: Tags: Conditions Palliative Care Source Type: blogs

Top 6 Companies Using AI In Drug Discovery And Development
What if coming up with a new drug could be measured in days rather than years? What if new medication would cost thousands instead of billions of dollars? Just look at how an AI pharma start-up developed a potential new drug in 46 days! Artificial intelligence technologies promise to speed up the process of drug discovery and development and make it more cost-effective. As the market is flourishing, and it takes time and effort to separate the wheat from the chaff, we collected the most promising AI pharma companies out there. Drug design is a key area AI is revolutionizing. In one of our latest database projects, we de...
Source: The Medical Futurist - August 17, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Pharma Genomics research clinical trials AI drug development medication drug discovery drug research cure Source Type: blogs

Removing workflow burdens and improving access for colorectal cancer screenings
After much outcry, UnitedHealthcare announced that they are no longer moving forward with their controversial prior authorization policy that would require members to get approval from the insurance company to receive a diagnostic colonoscopy to detect cancer. Instead, UnitedHealthcare has discussed implementing an alternative: an advanced notification process that would require physicians to collect and Read more… Removing workflow burdens and improving access for colorectal cancer screenings originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 16, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Going the Extra Mile to Support Patient Access Is a Win-Win for Patients and HIE Compliance
The following is a guest article by Deven McGraw, Co-Founder of Ciitizen® and Lead for Data Stewardship and Data Sharing at Invitae Corporation HIEs and HINs Should take Key Actions Now to Prepare for the Enforcement of the Information Blocking Rules On Sept. 1, 2023, enforcement of the 21st Century Cures Act Information Blocking Rule goes into effect, putting teeth into the much-celebrated law that enables patients to have full access to their personal health data. Some health information exchanges and health information networks (HIEs) have been preparing for this moment, knowing full well the steep statutory penalties...
Source: EMR and HIPAA - August 16, 2023 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership Health IT Company Healthcare IT HIM Interoperability Regulations Security and Privacy Carequality Ciitizen CommonWell Deven McGraw eHealth Exchange Health Data Sharing Health Information Exchanges Health Reco Source Type: blogs

Celebrating 10 Years of Biomedical Beat
This August marks 10 years of the blog! Throughout the past decade, we’ve brought you blog posts that explore basic science topics, quiz your knowledge, showcase cool images, and more! Some of our most-read favorites include: We’ve also interviewed over a hundred NIGMS-funded scientists about their research, mentorship, and careers. To celebrate 10 years, we went back to two of the first researchers featured on the blog to see what they’re up to now. Exploring Enzymes With Dr. Emily Scott Credit: University of Michigan. Around the time we first fe...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 16, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Molecular Structures Cool Tools/Techniques Profiles Research Roundup RNA Source Type: blogs

THCB 20th Birthday Classic:  As I’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT Our 20th birthday continues with a few classics coming out. Back in 2005 I was really cutting a lyrical rug, and would never miss a chance to get that Cambridge training in Marxism into use. This essay about whether health care should be a public or private good has always been one of my favorites, even if I’m not sure Starbucks is still making Frappuccinos. And 18 years later the basic point of this essay remains true, even if many of you will not have a clue who Vioxx or Haliburton were or why they mattered back then! Those of you who think I’m an unreconstructed commie will correctly suspec...
Source: The Health Care Blog - August 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Communism Frappuccinos Source Type: blogs

Survivors of Nuclear Weapon Use in Early Life Exhibit Accelerated Immune Aging in Late Life
It probably strains the meaning of the term to call the aftermath of the use of nuclear weapons at the end of the Second World War a natural experiment, but nonetheless there has been considerable study of survivors from those events and their health relative to control populations in other parts of Japan. Irradiation is known to produce what is effectively accelerated aging in the context of cancer treatment, producing an increased burden of senescent cells that then ensure the later course of health for survivors is worse than would otherwise be the case, absent both cancer and treatment. In the case of exposure to radia...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What Is Pharmacology?
Credit: iStock. Pharmacology is the study of how molecules, such as medicines, interact with the body. Scientists who study pharmacology are called pharmacologists, and they explore the chemical properties, biological effects, and therapeutic uses of medicines and other molecules. Their work can be broken down into two main areas: Pharmacokinetics is the study of how the body acts on a medicine, including its processes of absorption, distribution, metabolism, and excretion (ADME). Pharmacodynamics is the study of how a medicine acts in the body—both on its intended target and throughout all the organs and tissue...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 14, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Common questions Genomics Medicines Miniseries Source Type: blogs

A Selective Destruction Theory of Aging
At present the research community cannot robustly connect underlying causative processes of aging, such as those described in the SENS view of damage and rejuvenation, or some of the hallmarks of aging, to higher level manifestations of aging, such as declining function or changing biomarkers associated with age-related disease. This gives great freedom to theorize on how exactly the present voluminous but disconnected body of data on aging, cellular biochemistry, and age-related disease all fits together. There is no shortage of theories of aging, and no sign that the research community will cease to create new ones at an...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Browsing New comments
Any comments on this blog are moderated by me.  If they are a question related to the subject of the post, I will answer it (not always very quickly, I have to confess).But most are not related at all.   For example:Very complementary about my writing style, but included a link to private tutoring service.  Actually there were three at least like this;Opportunities to buy medications - separate offers of NSAIDs, pain medications, benzodiazepines, opioids, barbiturates...;Links to a homoeopathy clinic (as all these comments are, on posts not related to the subject of the comment);Recommendation...
Source: Browsing - August 13, 2023 Category: Databases & Libraries Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The future of medicine: Advancements and greed collide
In the future, I foresee a world without pandemics, cancer becoming a thing of the past, and advancements that enable bionic adaptations to our bodies, leading to a life expectancy of easily over one hundred years. While some of these advancements may seem distant, we are on the cusp of making them a reality within Read more… The future of medicine: Advancements and greed collide originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 12, 2023 Category: General Medicine Authors: Tags: Tech Health IT Source Type: blogs

Removal of the Thymus Illustrates the Importance of Thymic Atrophy in Aging
This study demonstrates just how vital the thymus is to maintaining adult health." Link: https://news.harvard.edu/gazette/story/2023/08/turns-out-lowly-thymus-may-be-saving-your-life/
Source: Fight Aging! - August 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs