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Fight Aging! Newsletter, April 15th 2019
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - April 14, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Out of Hospital Cardiac Arrest third leading cause of DALY
Disability Adjusted Life Years (DALY) following adult nontraumatic Out of Hospital Cardiac Arrest (OHCA) treated by Emergency Medical in the United States of America has been shown to be the third leading cause of DALY lost in the year 2016 [1]. DALY is a standardized public health measure for estimating and comparing the burden of disease to the society at large. Coute RA and associates used the data from US national Cardiac Arrest Registry to Enhance Survival database for 2016. Years of life lost was calculated from this data and the remaining life expectancy at the age of death. Cerebral performance category scores fr...
Source: Cardiophile MD - April 10, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

What Will Being Healthy Mean In The Future?
The objective is not “just” being healthy anymore but also being in the best shape possible. The healthy lifestyle craze that started in the 1980s is augmented with technologies and penetrates every area and moment of life. In his book, 21 Lessons for the 21st Century, Yuval Noah Harari argues that as technology encompasses every tiny part of our health, we will gradually let technology take over our decision-making capacities. In a couple of decades, tiny sensors and big data might tell us whether we are sick or healthy. Medical decisions in our life won’t rely on our feelings of illness or wellness, or even on t...
Source: The Medical Futurist - April 6, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Bioethics Health Sensors & Trackers AI doctor dystopia future Healthcare healthy healthy lifestyle history history of medicine Innovation patient philosophy progress technology Source Type: blogs

7 Practical Tools for Picking Yourself up During Your Darkest Days
You're reading 7 Practical Tools for Picking Yourself up During Your Darkest Days, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. These days most people experience some feelings of depression, anxiety, grief or general lack of motivation. This is a normal part of life, however, if we don’t take productive action, these states can linger and interfere with our functioning at work and in relationships. Here are some simple yet highly effective tools that can help you out of a dark period and propel you back towards balan...
Source: PickTheBrain | Motivation and Self Improvement - April 5, 2019 Category: Consumer Health News Authors: Tabitha Bailey Tags: depression featured self improvement motivation passion pickthebrain Source Type: blogs

Podcast: From Homeless to Prisoner to Olympian
 In his teens, Tony Hoffman was a BMX Amateur being featured on magazine covers. But soon after, he was a drug addict living in the streets and ultimately ending in prison. After his parole, a now clean Tony returned to the BMX world in a big way: by taking the silver medal in the 2016 Olympics. Since then, Tony has dedicated his life to helping others with addiction issues with his motivational speaking and special projects. Subscribe to Our Show! And Remember to Review Us! About Our Guest After paroling prison on December 13, 2008, Tony Hoffman started living out his dream, with his addiction behind...
Source: World of Psychology - April 4, 2019 Category: Psychiatry & Psychology Authors: The Psych Central Show Tags: General Recovery Sports The Psych Central Show Addiction BMX Gabe Howard Olympics prison Tony Hoffman Vincent M. Wales Source Type: blogs

Podcast: From Homeless to Prisoner to Olympic Coach
 In his teens, Tony Hoffman was a BMX Amateur being featured on magazine covers. But soon after, he was a drug addict living in the streets and ultimately ending in prison. After his parole, a now clean Tony returned to the BMX world in a big way: by taking the silver medal in the 2016 UCI BMX World Championships. Since then, Tony has dedicated his life to helping others with addiction issues with his motivational speaking and special projects. Subscribe to Our Show! And Remember to Review Us! About Our Guest After paroling prison on December 13, 2008, Tony Hoffman started living out his dream, with h...
Source: World of Psychology - April 4, 2019 Category: Psychiatry & Psychology Authors: The Psych Central Show Tags: General Recovery Sports The Psych Central Show Addiction BMX Gabe Howard Olympics prison Tony Hoffman Vincent M. Wales Source Type: blogs

New CNS Drug Delivery System by Alcyone Lifesciences Given Breakthrough Designation by FDA
Alcyone Lifesciences recently obtained Breakthrough Device Designation from the FDA for their novel implantable intrathecal bolus drug delivery catheter and port system, the ThecaFlex DRx System. The system is intended for use in conditions that requ...
Source: Medgadget - April 1, 2019 Category: Medical Devices Authors: Kurt Yaeger Tags: Neurology Neurosurgery Pain Management Radiology Source Type: blogs

Fight Aging! Newsletter, April 1st 2019
In conclusion, long-term aerobic exercise appears to attenuate the decline in endothelial vascular function, a benefit which is maintained during chronological aging. However, currently there is not enough evidence to suggest that exercise interventions improve vascular function in previously sedentary healthy older adults. Hijacking the Proteasome to Dispose of Unwanted Molecules in Age-Related Disease https://www.fightaging.org/archives/2019/03/hijacking-the-proteasome-to-dispose-of-unwanted-molecules-in-age-related-disease/ Cells are equipped with a protein disposal system in the form of the proteaso...
Source: Fight Aging! - March 31, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

7 Women Who Inspire Me
Proverbs 13:20 says, “Walk with the wise and become wise; associate with fools and get in trouble.” In other words, hang with the winners. A few months ago, my therapist gave me the assignment to think about the wise women in my life, warriors who had persevered through difficulties in their lives to emerge as stronger figures, examples of resilience who could serve as my teachers. I went even further and interviewed each one, asking them about the force or philosophy behind their strength. The following women have survived illness, divorce, deaths, lay-offs, but pressed on with a tenacity that inspires me. They are wo...
Source: World of Psychology - March 27, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Inspiration & Hope Mental Health and Wellness Self-Help Women's Issues Source Type: blogs

Nanotechnology Will Break The Curse Running Through Generations
A fictional tale about the healing power of technology The mutation of the CDH1 gene determines the fate of generations of men in a Czech small town. The great-grandfather dies unexpectedly upon returning home from the trenches of the first World War – he survives the bullets of the Italian front but gives in after a pint of beer and schnitzel. The grandfather was already diagnosed with an illness, gastric cancer, which required the removal of his entire stomach – but his life couldn’t be saved either. His son was luckier, he was diagnosed in time with an early stage hereditary diffuse gastric cancer and had e...
Source: The Medical Futurist - March 23, 2019 Category: Information Technology Authors: nora Tags: Medical Science Fiction Nanotechnology in Medicine cancer generation genetic disorder genetics Innovation sci-fi Surgery Source Type: blogs

What It Means to Be a Mental Health Advocate —And How to Become One
Over the years, the stigma surrounding mental illness has significantly decreased. One of the biggest reasons? Mental health advocates. These are the individuals who tirelessly share their stories in all sorts of ways. They remind us that we’re not alone in our struggles—and there is real, tangible hope and healing. They shatter stereotypes and myths about mental illness, helping the public see that people with mental illness are just people. As Jennifer Marshall said, “By showing the world that we’re your neighbor, your family members, your friends, and we are not only surviving with these conditions, but t...
Source: World of Psychology - March 21, 2019 Category: Psychiatry & Psychology Authors: Margarita Tartakovsky, M.S. Tags: Disorders General Inspiration & Hope Mental Health and Wellness Peer Support Policy and Advocacy Psychology Psychotherapy Self-Help Stigma Suicide Treatment Source Type: blogs

Friendships – The Key To Happiness
You're reading Friendships – The Key To Happiness, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. I often recommend to others who seek to do what I tried, DON’T! It is too dangerous – you are taking an awful risk. It is not wise to isolate yourself for twelve months and spend hour upon hour peering inside, facing your worst pains and fears, trying to see beyond them for answers that might not even exist. And yet, if I hadn’t taken that gamble, I would have never understood today just how imperative friendship...
Source: PickTheBrain | Motivation and Self Improvement - March 20, 2019 Category: Consumer Health News Authors: Dr Winfried Sedhoff Tags: featured happiness psychology relationships friendship pickthebrain self improvement Source Type: blogs

The Benefits of Christian Faith
DiscussionFor Non-Christians1. In light of what you read about why you might want to enter the faith, have you changed your mind? Why or why not?For Christians1. In your experience with personal evangelism, which, if any, of the reasons presented here have you found to be effective?2. Think of two more benefits to salvation in addition to those discussed in this chapter.For both Christians and Non-Christians1. Of the reasons for wanting to become a Christian, which two do you find personally most appealing or most persuasive? Why?2. Of the reasons for wanting to become a Christian, which two do you find personally least ap...
Source: The Virtual Salt - March 14, 2019 Category: Neurology Authors: Robert Harris Source Type: blogs

10 Reasons Why Digital Health Start-Ups Go Bust
While the digital health market is expanding rapidly, ninety percent of start-ups will probably die within two to five years from their inception. That’s an awfully high number, so we looked around what could possibly go wrong with digital health start-ups to avoid the undeserving fate of falling into the abyss. Being an entrepreneur is tough – especially in healthcare As currently there’s an app for everything, you thought you make one that estimates the time needed to deliver food – so anyone could order pad thai from the closest place possible. Every single entrepreneur knows that a good idea is as a tiny ...
Source: The Medical Futurist - March 14, 2019 Category: Information Technology Authors: nora Tags: Business Health Sensors & Trackers Healthcare Design business model companies digital health digital health startups entrepreneurship future healthcare data Innovation patient design scientific scientific validation technology Source Type: blogs

Podcast: Talking Suicide with a Bipolar and a Schizophrenic
 Suicide is something that most people think they understand, but there are many misconceptions about it. We say it’s a serious problem, yet will mention it casually and insensitively in certain settings. In this episode, our hosts openly discuss suicide and their personal stories with trying to end their own lives.   SUBSCRIBE & REVIEW “I thought about suicide every day for as far back as I can remember.” – Gabe Howard   Highlights From ‘Suicide’ Episode [1:00] Frankly discussing suicide. [3:00] Don’t belittle a person’s suicide attempt. [7:00] Why did Michelle try to end her...
Source: World of Psychology - March 11, 2019 Category: Psychiatry & Psychology Authors: A Bipolar, a Schizophrenic, and a Podcast Tags: A Bipolar, A Schizophrenic, and a Podcast Depression Schizophrenia Suicide Source Type: blogs