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The New Deal and Recovery, Part 18: The Recovery So Far
George Selgin(Although my contributions to this series have so far been more-or-less in their proper order, this one isn ' t: it occurred to me only relatively recently that it would be worthwhile to take stock of the overall progress of the recovery up to the outbreak of the Roosevelt Recession before delving into that episode. Had I done this in the first place, this installment would be Part 10 of the series, with the present Part 10 and all subsequent installments moved up a notch. –Ed.)When it struck down the Agricultural Adjustment Act in January 1936, the Supreme Court dropped the final curtain on the original New...
Source: Cato-at-liberty - June 1, 2022 Category: American Health Authors: George Selgin Source Type: blogs
The Reckoning: What Happens to Digital Health After COVID?
By JEFF GOLDSMITH and ERIC LARSEN
It has been a rough year so far for digital health. After an astonishing $45 billion poured into new digital health companies in 2020 and 2021, and an early 2021 peak in market valuations of publicly-traded digital health providers, valuations and multiples have collapsed. Once high-flying Teladoc, which traded at an eye-watering 42x revenues and commanded a $45 billion market capitalization, is now trading around 2.7X at about $5.7 billion. AmWell, the next largest telehealth player, has seen its stock drop more 90% from its high.
Nor is the evaporation in market value is co...
Source: The Health Care Blog - May 9, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Tech digital health Digital health investing Eric Larsen Healthcare bubble Jeff Goldsmith Source Type: blogs
Ukraine ’ s Secret Weapon – “ Moral Superiority ”
BY MIKE MAGEE
Two hundred and ten years ago, on September 7, 1812, a Putinesque commander, narrowly won a battle, but lost a war and entered a downward cycle that ended his reign. The battle was the Battle of Borodino, a town on the river Moskva, 70 miles west of Moscow. The commander was Napoleon.
The facts are clear-cut: Napoleon arrived with 130,000 troops, including his 20,000 Imperial Guards, and 500 guns. Opposing him were 120,000 Russians with 600 guns. The battle engaged from 6 AM to Noon. The French took 30,000 casualties, while the Russians lost 45,000 men, but survived to fight another day.
As Leo Tolst...
Source: The Health Care Blog - April 5, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Public Health Mike Magee Ukraine Source Type: blogs
Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, January 24th 2022
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols.
FOXO3...
Source: Fight Aging! - January 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Optical Biopsy to Spot Tumors Among Healthy Tissue
Researchers at Orel State University in Russia have developed a biopsy system that can distinguish between healthy and cancerous tissue in many clinical cases. The device is designed to address the difficulties that clinicians may experience when try...
Source: Medgadget - January 12, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Oncology Pathology Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
December 16 2021 Edition ----- On the global stage we are getting an increasing feeling that the old world order that resulted from the 2nd World War is breaking down with China and Russia both stirring up trouble. It all seems to be spinning out of control! – Climate Change also seems to be out of control with crazy weather all over! Tornadoes in the US a current example! Elsewhere the COVID seems to be coming back with a vengeance in the UK, Europe and the US – and Asia also getting worse. Christmas looks to be under threat a little. In OZ we are into the pre-Christmas slow down but with frenzied pre-election positio...
Source: Australian Health Information Technology - December 16, 2021 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, November 8th 2021
In conclusion, in less common and visible cardiovascular diseases, it is crucial to recognize substantial progress and achievement, given that penetration of such information into clinical practice and the patient community can be inconsistent. Diseases such as hypertrophic cardiomyopathy, pulmonary arterial hypertension, and ATTR cardiac amyloidosis, once linked to a uniformly adverse prognosis, are now associated with the opportunity for patients to experience satisfactory quality of life and extended longevity.
VitaDAO, a Novel Approach to Crowdfunding Life Science Research
https://www.fightaging.org/archive...
Source: Fight Aging! - November 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Khavinson Peptides for Thymic Regrowth
The objective here is to produce doses of the peptides dissolved in 0.5 ml of phosphate buffered saline in sealed vials, ready to be used with the injection system, with as little contamination as possible from the environment, and stored a freezer until it is ready to use. Depending on the size of the vial, it might be able to contain doses for multiple injections, but it is better to stick to one dose per vial. Peptides are sensitive to free-thaw cycles, so you want as few of those as possible.
When ordering epitalon, thymogen, and vilon, they will arrive as lyophilized (freeze-dried) crystals or powder. Thymogen ...
Source: Fight Aging! - November 1, 2021 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
The Fable of the Cats
George SelginThe comparison has by now been made so often that it may qualify as a platitude. I mean that between stablecoin issuers and “wildcat” banks, the fly‐by‐night scams that supposedly flooded the antebellum United States with notes nominally worth some stated amount of gold or silver, but actually worth little more than the rag paper they were made of.Such disreputable stuff, we keep hearing, is what “private” currency always tends to be like. The paper sort survived until federal authorities nationalized the nation’s paper money during the Civil War. And (we are told), digital currency will...
Source: Cato-at-liberty - July 6, 2021 Category: American Health Authors: George Selgin Source Type: blogs
We Like The Original Versions Of Abstract Artworks More Than Colour-Shifted Ones
By Emma Young
Take a look at this 1930 painting, “Rhythm, Joy of Life”, by French artist Robert Delaunay. Do you find it colourful? And do you like it?
Robert Delaunay – Rhythm, Joy of Life (1930)
Now what if every pixel in a digital version was rotated an equal distance on a “colour wheel” that represents every colour that people can see? Technically, the number of different colours in the image would be the same — but you’d probably perceive it to be less colourful. And, even if you’d never seen the original before, you’d probably like it less. That, at least, is the con...
Source: BPS RESEARCH DIGEST - June 21, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Perception Source Type: blogs
Fight Aging! Newsletter, May 31st 2021
In conclusion, iMSC-sEVs could rejuvenate the senescence of NPCs and attenuate the development of IVDD.
Cell Signaling via Exosomes in the Development of Vascular Calcification
https://www.fightaging.org/archives/2021/05/cell-signaling-via-exosomes-in-the-development-of-vascular-calcification/
Vascular calcification is a feature of aging, a process in which cells in the blood vessel wall take on inappropriate identities and activities that are more appropriate to bone tissue. Evidence of recent years implicates chronic inflammation and the presence of senescent cells in this process. Senescent cells caus...
Source: Fight Aging! - May 30, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Nanoparticles On My Mind
By KIM BELLARD
Nanoparticles are everywhere! By that I mean, of course, that there seems to be a lot of news about them lately, particularly in regard to health and healthcare. But, of course, literally they could be anywhere and everywhere, which helps account for their potential, and their potential danger.
Let’s start with one of the more startling developments: a team at the University of Miami’s College of Engineering, led by Professor Sakhrat Khizroev, believes it has figured out a way to use nanoparticles to “talk” to the brain without wires or implants. They use “a novel clas...
Source: The Health Care Blog - March 23, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard nanoparticles Source Type: blogs
Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases.
Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain.
From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
