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Processed Snacks and Desserts: What the Hell, Let's Have Some!
 viaflickrBy Crabby McSlackerAre you one of those people who eats only healthy whole foods, having absolutely no desire to consume tasty and convenient items created in some huge factory somewhere, packaged up and shipped thousands of miles away to your very own neighborhood grocery store?Well, congratulations!Enjoy that little cute little plate of fresh cut veggies and hummus. Savor that teeny-tiny handful of raw nuts. Arrange those fresh apple slices into a Pinterest-ready photo broadcasting your virtue.Me? Sometimes I buy processed stuff in boxes and bags and cartons and resealable pouches.My meals are generally pr...
Source: Cranky Fitness - October 18, 2017 Category: Consumer Health News Authors: Crabby McSlacker Source Type: blogs

Fight Aging! Newsletter, October 16th 2017
In this study, we have shown that the lipid chaperones FABP4/FABP5 are critical intermediate factors in the deterioration of metabolic systems during aging. Consistent with their roles in chronic inflammation and insulin resistance in young prediabetic mice, we found that FABPs promote the deterioration of glucose homeostasis; metabolic tissue pathologies, particularly in white and brown adipose tissue and liver; and local and systemic inflammation associated with aging. A systematic approach, including lipidomics and pathway-focused transcript analysis, revealed that calorie restriction (CR) and Fabp4/5 deficiency result ...
Source: Fight Aging! - October 15, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Tiny Breath Acetone Sensor to Measure Fat Burning During Exercise, Help Monitor Diabetes
Those wishing to lose weight have to watch their diet, but for optimal results they also have to burn existing fat in their bodies through exercise. Any amount of exercise simply won’t do, as body fat only burns when pressed to do so by specifi...
Source: Medgadget - October 13, 2017 Category: Medical Devices Authors: Editors Tags: Sports Medicine Source Type: blogs

Recuperating (Or Being A Bad Patient)
I am recuperating from my surgery. It has been 8 days now. I am starting to get to the annoyed stage. The seriously annoyed stage.First of all, I am stuck wearing this dumba$$ knee brace which does not fit. It is too big for me. I can ' t tighten the lowest strap to be useful. If I am wearing anything underneath it (including the TED compression stocking I am supposed to wear every day for the next three weeks - which is not happening), it just slides down my leg. So I am stuck wearing shorts. Today is a little chilly for shorts but that ' s why I have sweaters. I am supposed to wear it 24/7 except when showering.Second, I...
Source: Caroline's Breast Cancer Blog - October 13, 2017 Category: Cancer & Oncology Tags: behavior being a patient boring cooking knee surgery Source Type: blogs

Immune Cell Telomeres and Senescence in the Context of Viral Infection and Aging
In this study, we sought to measure the in vivo changes of telomere length, inflammation-related cytokine and anti-CMV antibody titer with age and to determine the trajectory of these age-associated immune changes and their inter-relationship using longitudinal analysis over an average of 13 years. Specifically, we assessed the individual longitudinal trajectories of peripheral blood mononuclear cell (PBMC) telomere length, eight pro-inflammatory cytokines, and anti-CMV IgG titer in 456 subjects. Strikingly, aging-associated changes in these variables occur with a distinct trajectory in each individual. Thus, immune aging ...
Source: Fight Aging! - October 13, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Having Fun With Other Friends
Recently I blogged about being aggravated and frustrated when having lunch with a couple of old friends. I was very upset by the end of that lunch so much that I woke up aggravated and frustrated the next morning. I knew it was time for a change. I won ' t be spending much time with either of them any more. I know they are upset. Well I am upset too. Sometimes its like talking to a brick wall with some people.Since cancer, I can no longer count the number of friends I have lost. There was one old friend who I reconnected with on Facebook after breast cancer. We were talking about lunch sometime, until I told her about my b...
Source: Caroline's Breast Cancer Blog - October 3, 2017 Category: Cancer & Oncology Tags: friends having fun stress Source Type: blogs

Pinktober
Its now Pinktober. It will be horrible. There will be pink on everything. There were even little pink ribbons on the bananas I bought last week. I was appalled but I didn ' t notice until I got home and it was too lazy to bring them back.But please brace yourself and do not get sucked into the pinkification which will be rampant all month long. Please do not purchase anything or donate to anything that claims to support breast cancer unless you know the following:The organization to which the money is going - are they a real organization that really will use the funds to provide what they said they will.That the total amou...
Source: Caroline's Breast Cancer Blog - October 1, 2017 Category: Cancer & Oncology Tags: donating pink washing pinkification pinktober research Source Type: blogs

I Am A Klutz
Today I was at an event where I might have fallen a tiny bit. I must say I am not completely unfamiliar with the room because I was in that same room in 1989 or so at a friend ' s wedding. So I must have memorized the entire room layout then (although I know alcohol was involved at the wedding).But things might have gotten a little hazy since.But my question is who carpets an entire room with the same carpet on everything except the dance floor? By the carpets rest of the room I mean stairs that go across the full length of the room and the DJ/band riser at the end of the space. In a dark blue carpet which shows no contour...
Source: Caroline's Breast Cancer Blog - September 30, 2017 Category: Cancer & Oncology Tags: avoidance blogging falls pain Source Type: blogs

Aggravated, Frustrated, And More
Yesterday I had lunch with two friends who I have known for a very long time. One since the 1970s and the other since the 1980s. While I have sensed over the years they do not understand what I am going through. Yesterday revealed the truth. They do not have a clue. I was so aggravated when I left lunch and I woke up aggravated about it this morning. They were insensitive, self centered, and ignorant of my limitations.I made a lunch reservation and had hoped to be there first so I could get a table with chairs and not a padded bench, which can sometimes be difficult for my back. As my friend, A, was already seated, I decid...
Source: Caroline's Breast Cancer Blog - September 25, 2017 Category: Cancer & Oncology Tags: aggravation disappointment friends idiots stupidity Source Type: blogs

Lorazepam, Haloperidol, and Delirium
JAMA Internal Medicinehas published a double-blind,randomized, placebo-controlled trial of adding lorazepam to haloperidol in patients with advanced cancer and agitated delirium. (We had a heads up about this trial because it waspresented at ASCO earlier this year.) If there ever was a sort of consensus in HPM about how we should be treating delirium, my sense is that it ’s been shattered by the recentRCT of low-dose haloperidol vs risperidone for delirium in Australian palliative care unit patients, showing those drugsworsened delirium symptoms. So, it seems like we should all see what we can learn from this newly publi...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 25, 2017 Category: Palliative Care Tags: antipsychotics delirium research issues rosielle Source Type: blogs

Well, Crapola!
A few weeks ago, I posted about whatmy pain medication may hide, yesterday I found the truth. Call me slow about some things but I had to do some thinking.I have RA, fibromyalgia, bad back, etc - all sorts of nice things that cause pain. So I get the good drugs. I have this awesome pain patch that masks 99% of it. It wasn ' t until I was an idiot a few weeks ago and forgot to change my pain patch I had no idea how much pain.The thinking process I had to go through was what was all that pain from and why is it important? I know several people that have RA as well, my mother and an old friend. Both of them are on injected bi...
Source: Caroline's Breast Cancer Blog - September 20, 2017 Category: Cancer & Oncology Tags: aggressive ailments arthritis treatment medical crap rheumatoid arthritis Source Type: blogs

Surviving Life With Ailments
What is the best way to survive ailments? First of all, one step at a time. And take as many breaks as possible to have fun.That is what I did today. I may have my feet up recovering but I had fun, with my husband.Today we went to a museum and out for lunch looking at the ocean. My feet are really tired. My knees hurt. My hips are speaking up too.But by spending a few hours out doing something outside our normal activities it was a nice break. I didn ' t have to think about any of my medical ailments (until my feet started to hurt) or upcoming medical misadventures - which includes knee arthroscopy in a couple of weeks.It ...
Source: Caroline's Breast Cancer Blog - September 13, 2017 Category: Cancer & Oncology Tags: being a patient enjoyment fun Source Type: blogs

What Does Your Pain Medication Hide?
Last weekend I was a total idiot and forgot to change my pain patch for so long my RA was causing me agony. But I also felt pain in other places that I did not expect. My RA pain was definitely the worst of all.What this little spurt of idiocy tells me that my pain meds, especially my pain patch, are working and do take care of my pain. This is a very nice thing to know. I am not living in pain (most of the time) because of them.But then what concerns me is what are my pains caused by. Okay, I am no idiot but I do know that what I felt in my hands and feet is caused by my RA. But then I have pain in other places that I did...
Source: Caroline's Breast Cancer Blog - September 7, 2017 Category: Cancer & Oncology Tags: doctor questions pain levels pain management Source Type: blogs

Breast Cancer Treatment Benefits
Recently it was announced in a draft proposal that the UK ' sNHS would not cover faslodex to treat estrogen positive metastatic breast cancer. While this may be disappointing to some, at this point I agree with the decision.The reason given for the decision is:" While NICE [National Institute for Health and Care] Excellence acknowledged that it can stall tumour growth by up to three months compared to aromatase inhibitors, it said early evidence isn ’t strong enough to show that the drug extends survival. "What is the point of spending millions of dollars on patient medication if it does not extend survival? Th...
Source: Caroline's Breast Cancer Blog - September 4, 2017 Category: Cancer & Oncology Tags: breast cancer treatment metastatic cancer quality of life Source Type: blogs

I ' ve Been Sliding
The road to hell is paved with good intentions. I have been lazy this summer and taking it easy - in terms of not taking care of myself as much as I should. Why not? Summer time is nice weather. There is no snow and ice to trip me up. I usually feel better during the summer. But just because I feel better doesn ' t mean I can stop taking care of myself.With every doctor appointment, there are the reminders to eat healthy, blah, blah, blah. I usually reinforce my intentions. But I have been sliding, I have been lazy and haven ' t been taking care of myself. I have been pushing myself too much and not resting enough. I ...
Source: Caroline's Breast Cancer Blog - September 2, 2017 Category: Cancer & Oncology Tags: being healthy diet food Source Type: blogs