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Why are mRNA vaccines so exciting?
The very first vaccines for COVID-19 to complete Phase 3 testing are an entirely new type: mRNA vaccines. Vaccines of this type have never before been approved for use in any disease. How do they differ from traditional vaccines, and what makes them so exciting? How traditional vaccines work The main goal of a vaccine for a particular infectious agent, such as the virus that causes COVID-19, is to teach the immune system what that virus looks like. Once educated, the immune system will vigorously attack the actual virus, if it ever enters the body. Viruses contain a core of genes made of DNA or RNA wrapped in a coat of pro...
Source: Harvard Health Blog - December 10, 2020 Category: Consumer Health News Authors: Anthony Komaroff, MD Tags: Coronavirus and COVID-19 Health Vaccines Source Type: blogs

Planning for Future Pandemics Including Smallpox Outbreaks: Interview with Dr. Phil Gomez, CEO, SIGA Technologies
The COVID-19 pandemic has had significant global consequences, with healthcare systems stretched to their limits, a growing death toll, and economic devastation as economies came grinding to a halt. The pandemic and its aftereffects will be with u...
Source: Medgadget - May 27, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Public Health Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been awa...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs

Reasons to chill and reasons not to chill
Okay, I ' m not an epidemiologist or a virologist. But I do know something about those subjects, I ' m a public health professor, and I am an expert in clinical communication and risk communication. So I ' m going to offer some observations that I hope will help people keep this public health scare in proper perspective and maybe be of practical use.There are two important parameters we need to understand the risk caused by any communicable disease. I ' m going to broadly say transmissibility, and the probability that exposure will lead to serious disease.We often see transmissibility represented as a single number, called...
Source: Stayin' Alive - February 26, 2020 Category: American Health Source Type: blogs

On the RISE: Joshua and Caleb Marceau Use NIGMS Grant to Jump-Start Their Research Careers
A college degree was far from the minds of Joshua and Caleb Marceau growing up on a small farm on the Flathead Indian Reservation in rural northwestern Montana. Their world centered on powwows, tending cattle and chicken, fishing in streams, and working the 20-acre ranch their parents own. Despite their innate love of learning and science, the idea of applying to and paying for college seemed out of reach. Then, opportunities provided through NIGMS, mentors, and scholarships led them from a local tribal college to advanced degrees in biomedical science. Today, both Joshua and Caleb are Ph.D.-level scientists working to imp...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 23, 2019 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Infectious Diseases Scientific Process Training Source Type: blogs

The Luxury to Choose
By TRAVIS BIAS, MD The 80 year-old woman lay on her mat, her legs powerless, looking up at the small group that had come to visit her. There were no more treatment options left. The oral liquid morphine we had brought in the small plastic bottle had blunted her pain. But, she would be dead in the coming days. The cervical cancer that was slowly taking her life is a notoriously horrible disease if left undetected and untreated and that is exactly what had happened in this case. We had traveled hours by van along dirt roads to this village with a team of health workers from Hospice Africa Uganda, the country’s authority o...
Source: The Health Care Blog - February 25, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Gardasil Hospice Africa Uganda vaccines Source Type: blogs

Digital Maps Help Fight Epidemics
Have you ever thought that it would be possible to monitor drug overdoses, Zika cases or the spread of the flu in real time? Have you ever imagined that satellites wouldbe able to tell how and where a malaria epidemic will happen months before the actual outbreak? It is mind-blowing how, in the last years, digital maps developed to a level where they serve as effective tools for evaluating, monitoring and even predicting health events. That’s why I decided to give a comprehensive overview of digital maps in healthcare. John Snow, cholera and the revolution of maps in healthcare Before Game of Thrones monopolized John Sn...
Source: The Medical Futurist - October 12, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine Healthcare Design Mobile Health digital health digital technology epidemics epidemiology gc4 Innovation interactive maps Source Type: blogs

Why Doctors should read books by Nassim Taleb
By SAURABH JHA, MD     “There are some enterprises in which a careful disorderliness is the true method” Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathem...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Why Doctors (And Everybody Else) Should Read Books by Nassim Taleb
By SAURABH JHA, MD “There are some enterprises in which a careful disorderliness is the true method” – Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathematicia...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Why President Trump Should Use Foreign Aid For Health To Make America Great
The Trump administration recently proposed to make major cuts to US foreign assistance, including the $10.3 billion a year that the federal government spends to advance global health through the National Institutes of Health (NIH), the Centers for Disease Control and Prevention, the US Agency for International Development (USAID), and the United Nations. As practitioners with more than 60 years of combined experience, we believe that the Trump administration is making a terrible mistake. Investing in global health is essential to the safety, security, and future prosperity of the United States, in addition to being a highl...
Source: Health Affairs Blog - April 17, 2017 Category: Health Management Authors: Robert Hecht and Sten Vermund Tags: Costs and Spending Featured Global Health Policy Population Health Public Health epidemics foreign aid humanitarian aid infectious diseases PEPFAR US foreign assistance Source Type: blogs

The Law of Diminishing Returns of Ethicism
SAURABH JHA MD Many allege that the FIRST trial, which randomized surgical residencies to strict versus flexible adherence to duty hour restrictions, was unethical because patients weren’t consented for the trial and, as this was an experiment, in the true sense of the word, consent was mandatory. The objection is best summarized by an epizeuxis in a Tweet from Alice Dreger, a writer, medical historian, and a courageous and tireless defender of intellectual freedom. @RogueRad @LVSelbs @ethanjweiss @Skepticscalpel Consent to experimentation. Consent. Consent. Am I not being clear? — Alice Dreger (@AliceDreger) Nov...
Source: The Health Care Blog - March 20, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Uncategorized Source Type: blogs

Online Virus Tracking Tool Nextstrain Wins Inaugural Open Science Prize
Credit: Trevor Bedford and Richard Neher, nextstrain.org. Over the past decade, scientists and clinicians have eagerly deposited their burgeoning biomedical data into publicly accessible databases. However, a lack of computational tools for sharing and synthesizing the data has prevented this wealth of information from being fully utilized. In an attempt to unleash the power of open-access data, the National Institutes of Health, in collaboration with the Howard Hughes Medical Institute and Britain’s Wellcome Trust, launched the Open Science Prize . Last week, after a multi-stage public voting process, the inaugural awa...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - March 10, 2017 Category: Research Authors: Chris Palmer Tags: Computers in Biology Bioinformatics Ebola Genomics Infectious Disease Spread Infectious Diseases Modeling Viruses Zika Source Type: blogs

ACA Repeal Would Mean Massive Cuts To Public Health, Leaving Cities And States At Risk
When the Affordable Care Act (ACA) was passed a little over six years ago, it brought with it the promise of health insurance for all Americans. It also sought to begin to shift the paradigm for health care in this country, emphasizing value over volume, and recognizing the importance of prevention coupled with appropriate access to care. By now, it is well known that repealing the ACA could leave nearly 20 million Americans uninsured and simultaneously result in millions of job losses across the country. An associated cost that has been less discussed, but no less relevant, is what repeal could mean for the nation’s alr...
Source: Health Affairs Blog - March 7, 2017 Category: Health Management Authors: Chrissie Juliano Tags: Costs and Spending Following the ACA Public Health Big Cities Health Coalition Community Health Prevention and Public Health Fund. Source Type: blogs

Profit over Safety – Centers for Disease Control Names 271 New Vaccinations
Conclusion How many vaccinations will be considered to be a sensible number? If all of the vaccinations currently under development are deemed a success, how many of them will be added to the schedule? As there is little research to determine which ingredients are in the vaccinations listed as “under development” by the CDC, many parents are concerned about their toxicity and how best to protect their children. I will leave you with the wise words of Robert F, Kennedy Jr: “Vaccine industry money has neutralized virtually all of the checks and balances that once stood between a rapacious pharmaceutical industry and ou...
Source: vactruth.com - August 3, 2015 Category: Allergy & Immunology Authors: Christina England Tags: Top Stories Christina England Logical Centers for Disease Control (CDC) World Health Organization (WHO) PhRMA Robert F. Kennedy Jr. Source Type: blogs