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Total 3278 results found since Jan 2013.

Effectiveness of the physiotherapy interventions on complex regional pain syndrome in patients with stroke: A systematic review and meta-analysis
This study reviewed the available literature of physiotherapy treatment for CRPS following a stroke.
Source: Journal of Bodywork and Movement Therapies - April 28, 2023 Category: Physiotherapy Authors: Kanika, Manu Goyal, Kanu Goyal Source Type: research

Characterizing biased visuospatial perception in complex regional pain syndrome
ConclusionsPatients' cognitive strategies will be important to consider when studying inter-individual differences in the cognitive symptomatology and associated cognitive-based rehabilitation procedures in CRPS.SignificanceThe existence of biases in visuospatial perception in Complex Regional Pain Syndrome has been reported but not always systematically replicated. We show that these biases might depend on the type of general rehabilitation program that the patients follow. Patients ’ individual cognitive strategies will be important to consider when studying the cognitive symptomatology of CRPS.
Source: European Journal of Pain - April 22, 2023 Category: Anesthesiology Authors: Lieve Filbrich, Avgustina Kuzminova, Victoria Molitor, Charlotte Verfaille, Dominique Mouraux, Anne Berquin, Olivier Barbier, Xavier Libouton, Val éry Legrain Tags: ORIGINAL ARTICLE Source Type: research

Effect Analysis of Different Environmental Disinfection Methods on Reducing Contamination of Surfaces by the Omicron BA.2.2 Variant of SARS-CoV-2 and the Characteristics of Fomite Contamination in the Fever Clinic in the Out-Broken of Shanghai
This study aimed to investigate the effect of different environmental disinfection methods on reducing contaminated surfaces (CSs) by the Omicron BA.2.2 variant of SARS-CoV-2 in the fever clinic between March 20 and May 30, 2022, and to analyze the influences and related factors of CSs. This study includes survey data from 389 positive patients (SPPs) and 204 CSs in the fever clinic, including the CS type, disinfection method, length of time spent in the clinic, cycle threshold (CT) value, name, age, weight, mask type, mask-wearing compliance, hand-mouth touch frequency and sex. Associations between study variables and spe...
Source: Food and Environmental Virology - April 17, 2023 Category: Virology Source Type: research

Partial Scapholunate Interosseous Ligament Injuries: A Systematic Review of Treatment Options
Conclusion All interventional treatment options (ES, AC, and OC) provided significant improvements in patient-reported pain, range of motion, grip strength, and radiographic parameters, with low complication rates. In comparison, no improvement in range of motion or grip strength was noted in the NT group. Therefore, surgical management of pSLIL injuries is an effective and relatively safe treatment option. Further studies comparing the outcomes of specific surgical treatments are warranted to further elucidate the optimal management option for pSLIL tears. Level of Evidence Level III, systematic review of Level III...
Source: Journal of Wrist Surgery - April 12, 2023 Category: Orthopaedics Authors: Lameire, Darius Luke Khalik, Hassaan Abdel Paul, Ryan Augustine von Schroeder, Herbert P. Chan, Andrea H. W. Tags: Survey or Meta-Analysis Source Type: research

The role of the bone in complex regional pain syndrome 1 —A systematic review
ConclusionThe limited data reviewed revealed certain potential bone-related biomarkers in CRPS. Biomarkers hold the potential to identify patients who may benefit from treatments that influence bone turnover. Thus, this review identifies important areas for future research in CRPS1 patients.
Source: European Journal of Pain - April 9, 2023 Category: Anesthesiology Authors: Gil Kollmann, Maria M. Wertli, Stefan Dudli, Oliver Distler, Florian Brunner Tags: REVIEW ARTICLE Source Type: research

Thyroid function and associated mood changes after COVID-19 vaccines in patients with Hashimoto thyroiditis
ConclusionCOVID-19 vaccination seemed to induce increased levels and incidence of TSH surge followed by mood changes in patients with HT. Higher levels of pre-vaccine serum TSH, CRP, and anti-TPO values were associated with higher incidence in the early post-vaccine phase.
Source: Frontiers in Immunology - April 6, 2023 Category: Allergy & Immunology Source Type: research

Prediction of the Efficacy of Lumbar Sympathetic Block in Patients with Lower Extremity Complex Regional Pain Syndrome Type 1 Based on the Sympathetic Skin Response
ConclusionsPatients with lower extremity CRPS-1 can experience significant pain relief after LSB treatment. The predictors of successful symptom relief after LSB treatment were a baseline SSR amplitude of the affected extremity  <  510 µV and a disease duration <  12 months.Trial RegistrationThe study was registered in the Chinese Clinical Trial Registry (ID: ChiCTR2000037755, date of registration: September 4, 2020).
Source: Pain and Therapy - April 4, 2023 Category: Anesthesiology Source Type: research

The role of the bone in Complex Regional Pain Syndrome 1 – A systematic review
AbstractThe aim of this systematic review was to appraise and analyze the knowledge on bone-related biochemical and histological biomarkers in Complex Regional Pain Syndrome 1 (CRPS 1).A total of 7 studies were included in the analysis (biochemical analyses n=3, animal study n=1, histological examination n=3). Two studies were classified as having low risk of bias and five studies with a moderate risk of bias. Biochemical analysis indicated an increased bone turnover with increased bone resorption (elevated urinary levels of deoxypyridinoline) and bone formation (increased serum levels of calcitonin, osteoprotegrin and alk...
Source: European Journal of Pain - April 1, 2023 Category: Anesthesiology Authors: Gil Kollmann, Maria M. Wertli, Stefan Dudli, Oliver Distler, Florian Brunner Tags: REVIEW ARTICLE Source Type: research

Keratinocyte PIEZO1 Contributes To Peripheral Sensitization In A Rat Model Of Complex Regional Pain Syndrome
Patients suffering from complex regional pain syndrome (CRPS) often present with debilitating mechanical allodynia in the skin of the affected limb. To explore the mechanism underlying peripheral nociceptive sensitization in CRPS and seek therapies targeting the periphery without affecting the central nervous system, we studied the role of keratinocyte mechanosensitive PIEZO1 channel in CRPS models. We induced ischemia-reperfusion (I/R) injury for establishing in vivo chronic post-ischemia pain (CPIP) rat model and in vitro oxygen-glucose deprivation reperfusion (OGD/R) cultured cell model to mimic CRPS.
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Jijun Xu, Bei Wen, Li Xu, Yuguang Huang Source Type: research

Skin Resident Memory T Cell Dysfunction In The Tibia Fracture Model Of Complex Regional Pain Syndrome
Complex regional pain syndrome (CRPS) is a debilitating chronic pain disorder that with no effective treatments. Several microRNA (miRNA) are commonly dysregulated in CRPS patient and tibia fracture model of CRPS (TFM) mice, including miR-25 which is associated with positive treatment outcomes in patients. Interestingly, these miRNAs are predicted to target several genes critical to resident memory T cell (Trm) function. We hypothesize that miRNA dysregulation contributes to the pathology of CRPS through regulation of skin Trm development and maintenance.
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Jason Wickman, Botros Shenoda, Rachel Van Duyne, Zachary Kline, Seena Ajit Source Type: research

Newly Repopulated Spinal Cord Microglia Exhibit A Unique Transcriptome And Coincide With Sex-Independent Pain Resolution
The transition from acute-to-chronic pain is important because underlying mechanisms may reveal targets for the treatment of chronic pain. Spinal cord microglial activation results from persistent neuronal hyperexcitability, and this can trigger feedforward synaptic plasticity that contributes to chronic pain. We used a targeted, inducible genetic microglial depletion strategy in the clinically relevant tibial fracture/casting model of complex regional pain syndrome (CRPS) to interrogate the contribution of microglia to pain progression.
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Caldwell M. Bridges, Lauren J. Donovan, Amy R. Nippert, Meng Wang, Shaogen Wu, Thomas E. Forman, Elena S. Haight, Nolan A. Huck, Claire E. Jordan, Aysha S. Gardner, Ramesh V. Nair, Vivianne L. Tawfik Source Type: research

Applying Pix2pix to Translate Hyperemia in Blood Pool Image into Corresponding Increased Bone Uptake in Delayed Image in Three-Phase Bone Scintigraphy
CONCLUSION: The model based on pix2pix generated increased uptake in delayed images matching the hyperemia in the blood pool image in inflammatory arthritis and CRPS.PMID:36998587 | PMC:PMC10043061 | DOI:10.1007/s13139-022-00786-y
Source: Molecular Medicine - March 31, 2023 Category: Molecular Biology Authors: Ki Seong Park Jang Bae Moon Sang-Geon Cho Jahae Kim Ho-Chun Song Source Type: research

Intermittent versus continuous esketamine infusions for long-term pain modulation in complex regional pain syndrome: protocol of a randomized controlled non-inferiority study (KetCRPS-2)
Complex regional pain syndrome (CRPS) is a chronic pain condition of an extremity. While achieving pain relief in CRPS is challenging, esketamine infusions can accomplish pain relief for several weeks post-inf...
Source: BMC Musculoskeletal Disorders - March 29, 2023 Category: Orthopaedics Authors: Thomas J. P. Mangnus, Maaike Dirckx, Krishna D. Bharwani, Sara J. Baart, Theodora A. M. Siepman, Ken Redekop, Willem A. Dik, Cecile C. de Vos and Frank J. P. M. Huygen Tags: Study protocol Source Type: research

Diagnosis and outcomes of 225 consecutive cases of crps of the hand
CONCLUSIONS: . Unlike CRPS, all patients in this series had a true, diagnosable condition explaining their clinical picture. Most patients who accepted to be operated had a favorable outcome.PMID:36952596 | DOI:10.1097/PRS.0000000000010454
Source: Hand Surgery - March 23, 2023 Category: Surgery Authors: Francisco Del Pi ñal Source Type: research

Long-term efficacy of spinal cord stimulation for chronic primary neuropathic pain in the contemporary era: a systematic review and meta-analysis
CONCLUSIONS: SCS is a viable option for management of chronic neuropathic pain secondary to FBSS and CRPS. However, data available for its long term efficacy remains scarce and show no further statistically significant results.PMID:36943763 | DOI:10.23736/S0390-5616.23.05930-1
Source: Journal of Neurosurgical Sciences - March 21, 2023 Category: Neurosurgery Authors: Kaneez Fatima Syed O Javed Aqsa Saleem Shayan Marsia Ramsha Zafar Komal Noorani Sahlish Kumar Sara M Ali Iqra Ismail Insiya Hashim Fatima A Ganatra Source Type: research