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Study profile: the Genetics of Glaucoma Study
Purpose
Glaucoma, a major cause of irreversible blindness, is a highly heritable human disease. Currently, the majority of the risk genes for glaucoma are unknown. We established the Genetics of Glaucoma Study (GOGS) to identify disease genes and improve genetic prediction of glaucoma risk and response to treatment.
Participants
More than 5700 participants with glaucoma or a family history of glaucoma were recruited through a media campaign and the Australian Government healthcare service provider, Services Australia, making GOGS one of the largest genetic studies of glaucoma globally. The mean age of the participants was...
Source: BMJ Open - August 3, 2023 Category: General Medicine Authors: Gharahkhani, P., He, W., Diaz Torres, S., Wu, Y., Ingold, N., Yu, R., Seviiri, M., Ong, J.-S., Law, M. H., Craig, J. E., Mackey, D. A., Hewitt, A. W., MacGregor, S. Tags: Open access, Ophthalmology Source Type: research
Molecules, Vol. 28, Pages 5846: Elucidation of Pharmacological Mechanism Underlying the Anti-Alzheimer & rsquo;s Disease Effects of Evodia rutaecarpa and Discovery of Novel Lead Molecules: An In Silico Study
Molecules, Vol. 28, Pages 5846: Elucidation of Pharmacological Mechanism Underlying the Anti-Alzheimer’s Disease Effects of Evodia rutaecarpa and Discovery of Novel Lead Molecules: An In Silico Study
Molecules doi: 10.3390/molecules28155846
Authors:
Lulu Zhang
Jia Xu
Jiejie Guo
Yun Wang
Qinwen Wang
Alzheimer’s disease (AD) is a brain disease with a peculiarity of multiformity and an insidious onset. Multiple-target drugs, especially Chinese traditional medicine, have achieved a measure of success in AD treatment. Evodia rutaecarpa (Juss.) Benth. (Wuzhuyu, WZY, i.e., E. rutaecarpa), a...
Source: Molecules - August 3, 2023 Category: Chemistry Authors: Lulu Zhang Jia Xu Jiejie Guo Yun Wang Qinwen Wang Tags: Article Source Type: research
Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
Conditions: Migraine; Headache Interventions: Drug: Magnesium Sulfate; Drug: Metoclopramide 10mg; Drug: Prochlorperazine (Compazine) Injection Sponsor: Advocate Health Care Completed
Source: ClinicalTrials.gov - August 1, 2023 Category: Research Source Type: clinical trials
Can restless legs syndrome be a predictor of parkinsonism in patients with migraine comorbid with hypertension?
Background:Up to 34% of migraines are accompanied by restless legs syndrome (RLS), due to damage to the dopaminergic system, as in Parkinson's disease (PD). We have studied whether RLS is a predictor of PD in migraine with concomitant hypertension.
Source: Parkinsonism and Related Disorders - August 1, 2023 Category: Neurology Authors: M. Gulova, M. Sanoeva, N. Panoeva Source Type: research
A puff of air up the nose could be used to stop the pain of migraines
The results of a small trial, presented at a meeting of the American Headache Society in Austin, Texas, in June, showed that almost half of those given the air blast treatment were pain-free afterwards.
Source: the Mail online | Health - July 31, 2023 Category: Consumer Health News Source Type: news
The Future Is Now: Innovative Ways Virtual Reality Is Revolutionizing Healthcare Marketing
The following is a guest article by Ali Williams, Freelance Writer
With there now totaling 171 million users of virtual reality (VR) around the globe, this innovative technology is revolutionizing almost every industry – and healthcare marketing is no exception. Since the healthcare sector is constantly evolving, marketers need to work to stay on top of new trends to create successful marketing campaigns. VR tech is a useful tool that can help you better engage with your target market, provide educational experiences, and open up new opportunities for growth.
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Source: EMR and HIPAA - July 31, 2023 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Ali Williams Body Language Data Collection Educational Experiences GlaxoSmithKline Healthcare Marketing Immersive Tours Innovative Technology Perth Childre Source Type: blogs
Visual Hallucinations: Psychiatric vs. Neurologic Causes Visual Hallucinations: Psychiatric vs. Neurologic Causes
Visual hallucinations can have a multitude of causes, from psychosis to migraines, brain tumors, neurodegenerative diseases, and more. Review their varying key characteristics in this paper.Current Psychiatry
Source: Medscape Today Headlines - July 26, 2023 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Major Targets involved in Clinical Management of Migraine
CONCLUSION: Migraine biomarkers such as CGRP, PACAP, NLRP3, Nitric oxide synthase, MMP9, and Serotonin could be targets for developing drugs. Present marketed medications temporarily reduce symptoms and pain and have serious cardiovascular side effects. It is suggested that herbal treatment may help prevent migraine attacks without adverse effects. Natural biomolecules that may give better treatment than the present marketed medication and full fledge research should be carried out with natural biomarkers by the Network Pharmacological approach.PMID:37488760 | DOI:10.2174/1567202620666230721111144
Source: Current Neurovascular Research - July 25, 2023 Category: Neurology Authors: Rapuru Rushendran Vellapandian Chitra Kaliappan Ilango Source Type: research
