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Major Targets involved in Clinical Management of Migraine
CONCLUSION: Migraine biomarkers such as CGRP, PACAP, NLRP3, Nitric oxide synthase, MMP9, and Serotonin could be targets for developing drugs. Present marketed medications temporarily reduce symptoms and pain and have serious cardiovascular side effects. It is suggested that herbal treatment may help prevent migraine attacks without adverse effects. Natural biomolecules that may give better treatment than the present marketed medication and full fledge research should be carried out with natural biomarkers by the Network Pharmacological approach.PMID:37488760 | DOI:10.2174/1567202620666230721111144
Source: Current Neurovascular Research - July 25, 2023 Category: Neurology Authors: Rapuru Rushendran Vellapandian Chitra Kaliappan Ilango Source Type: research
Migraine Home Remedies and 'Cures': What Really Works?
It’s understandable to want to do whatever it takes to make migraines stop. But some home remedies are better ideas than others.
Source: WebMD Health - July 24, 2023 Category: Consumer Health News Source Type: news
Beta-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
In conclusion, beta-blockers serve as an indispensable tool in the realm of modern medical treatment, particularly in managing a broad range of cardiovascular conditions.
Their unique mechanism of action, which includes decreasing heart rate and blood pressure, confers a significant cardio-protective effect.
This, combined with their versatility and the extensive clinical experience with their use, has cemented beta-blockers as a first-line treatment for various conditions, from hypertension and heart failure to anxiety and migraines.
Although beta-blockers present unique benefits, it’s crucial...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Mayo Clinic Minute: Managing migraines in the summer
Severe weather conditions are enough to give anyone a headache, but temperature fluctuations are even more problematic for migraine sufferers. Dr. Rashmi B. Halker Singh, a Mayo Clinic neurologist, says the weather can trigger some migraine patients. Watch the Mayo Clinic Minute https://youtu.be/M3rfDADYFEs Journalists: Broadcast-quality video (1:08) is in the downloads at the end of this post. Please courtesy: "Mayo Clinic News Network." Read the script. For some people, migraines are debilitating. The intense, throbbing…
Source: News from Mayo Clinic - July 24, 2023 Category: Databases & Libraries Source Type: news
Genes, Vol. 14, Pages 1482: Melkersson & ndash;Rosenthal Syndrome and Migraine: A New Phenotype Associated with SCN1A Variants?
This report also adds knowledge to the clinical spectrum of SCN1A alterations and suggests a potential overlap between MRS and FHM.
Source: Genes - July 20, 2023 Category: Genetics & Stem Cells Authors: Alessia Azzar à Ilaria Cassano Carla Lintas Fabio Pilato Fioravante Capone Vincenzo Di Lazzaro Fiorella Gurrieri Tags: Article Source Type: research
Efficacy and Safety of Galcanezumab as a Preventive Treatment for Episodic Migraine in South Korean Patients: A Post-Hoc Analysis of a Phase 3 Clinical Trial
CONCLUSIONS: Galcanezumab treatment demonstrated efficacy and a favorable safety and tolerability profile in South Korean patients with EM.PMID:37455511 | DOI:10.3988/jcn.2022.0180
Source: Journal of Clinical Neurology - July 17, 2023 Category: Neurology Authors: Byung-Kun Kim Soo-Jin Cho Jeong Hee Han Grazia Dell'Agnello Tommaso Panni Manho Kim Kyungmi Oh Heui-Soo Moon Min Kyung Chu Source Type: research
