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Cancer: Lung Cancer
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The value of radiomics model based on ultrasound image features in the differentiation between minimal breast cancer and small benign breast masses
CONCLUSION: The radiomics model based on ultrasound image features has a satisfied predictive ability for small breast masses, and is expected to become a potential tool for the diagnosis of MBC, and it is a zero cost (in terms of patient participation and imaging time).PMID:37712556 | DOI:10.1002/jcu.23556
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Shuyi Lyu Meiwu Zhang Baisong Zhang Jiazhen Zhu Libo Gao Yuqin Qiu Liu Yang Yan Zhang Source Type: research
ARHGAP21 inhibits epithelial-mesenchymal transition by inactivating the WNT signaling pathway in non-small cell lung cancer
CONCLUSION: ARHGAP21 downregulation can significantly promote the migration and metastatic ability of NSCLC possibly as a result of WNT signaling pathway activation, which reduces the ubiquitination of β-catenin by affecting the expressions of APC, GSK3β, and Axin.PMID:37712268 | DOI:10.12122/j.issn.1673-4254.2023.08.08
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Xie L Liu J Fang X Zhong J Lin F Chen Source Type: research
An Adaptable Nanoprobe Integrated with Quantitative T < sub > 1 < /sub > -mapping Mri for Accurate Differential Diagnosis of Multidrug-Resistant Lung Cancer
This article is protected by copyright. All rights reserved.PMID:37714524 | DOI:10.1002/adhm.202300684
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Aijun Shen Yanhong Sun Gangmin Wang Xianfu Meng Xihui Ren Qingxuan Wan Qi Lv Xiangbin Wang Jiong Ni Minghua Li Xiaolong Ma Yun Xu Yutao Jiang Fang Wang YingSheng Cheng Peijun Wang Source Type: research
The value of radiomics model based on ultrasound image features in the differentiation between minimal breast cancer and small benign breast masses
CONCLUSION: The radiomics model based on ultrasound image features has a satisfied predictive ability for small breast masses, and is expected to become a potential tool for the diagnosis of MBC, and it is a zero cost (in terms of patient participation and imaging time).PMID:37712556 | DOI:10.1002/jcu.23556
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Shuyi Lyu Meiwu Zhang Baisong Zhang Jiazhen Zhu Libo Gao Yuqin Qiu Liu Yang Yan Zhang Source Type: research
Insomnia Burden among Informal Caregivers of Hospitalized Lung Cancer Patients and Its Influencing Factors
CONCLUSION: Of the hospitalized patients with lung cancer, 51.9% experienced insomnia. Patients' ADL, ICs gender, alcohol consumption, underlying medical conditions, caregiving duration, and monthly expenses were influencing factors. Therefore, prompt screening and early intervention for ICs of patients with lung cancer is necessary.PMID:37711083 | DOI:10.3967/bes2023.099
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Chun Yan Li Yu Jian Song Lan Zhao Mu Hong Deng Rui Xin Li Xiao Ling Zhang Qiong Xuan Li Ying Shi Heng Yu Luan Yuan Yuan Sun Yi Hu Xiao Yong Sai Source Type: research
Treatment of inoperable large cell neuroendocrine lung cancer with single agent temozolomide
Acta Oncol. 2023 Sep 15:1-4. doi: 10.1080/0284186X.2023.2258444. Online ahead of print.NO ABSTRACTPMID:37713358 | DOI:10.1080/0284186X.2023.2258444
Source: Acta Oncologica - September 15, 2023 Category: Cancer & Oncology Authors: Annika Marie Ørting Malene Martini Clausen Patrick Soldath Rene H Petersen Ulrich Knigge Mikkel Andreassen Andreas Kj ær Seppo W Langer Source Type: research
Stereotactic Body Radiation Therapy for Oligoprogressive and Oligorecurrent Non-Small-Cell Lung Cancer
CONCLUSION: SBRT is a safe and viable treatment option for oligoprogressive and oligorecurrent NSCLC. Patients with 0 to 2 sites had better OS and longer TNT-D compared to those with 3 to 5 lesions.PMID:37714807 | DOI:10.1016/j.cllc.2023.08.015
Source: Clinical Lung Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Maryam Ebadi Colton Ladbury Jason Liu Adam Rock Mykola Onyshchenko Victoria Villaflor Miguel Villalona-Calero Ravi Salgia Erminia Massarelli Percy Lee Terence Williams Arya Amini Source Type: research
The value of radiomics model based on ultrasound image features in the differentiation between minimal breast cancer and small benign breast masses
CONCLUSION: The radiomics model based on ultrasound image features has a satisfied predictive ability for small breast masses, and is expected to become a potential tool for the diagnosis of MBC, and it is a zero cost (in terms of patient participation and imaging time).PMID:37712556 | DOI:10.1002/jcu.23556
Source: Clinical Lung Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Shuyi Lyu Meiwu Zhang Baisong Zhang Jiazhen Zhu Libo Gao Yuqin Qiu Liu Yang Yan Zhang Source Type: research
Immunotherapy for the elderly. Maybe the best option for lung cancer?
Cancer Treat Res Commun. 2023 Sep 12:100762. doi: 10.1016/j.ctarc.2023.100762. Online ahead of print.ABSTRACTLung cancer is usually diagnosed at advanced stage and systematic therapy is administered. New current diagnostic techniques such as the convex-endobronchial ultrasound, radial endobronchial ultrasound, cone beam ct, electromagnetic navigation and robotic bronchoscopy provide us with a high diagnostic yield. These techniques are minimal invasive and patients with comorbidities such as chronic obstructive pulmonary disease and heart failure can be diagnosed with minimal adverse effects. All these techniques provide s...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Paul Zarogoulidis Dimitris Matthaios Panagoula Oikonomou Christina Nikolaou Charalampos Charalampidis Chrysanthi Sardeli Source Type: research
LAPS score for individualized treatment of advanced EGFR-mutated non-small cell lung cancer receiving EGFR-TKIs with or without bevacizumab
CONCLUSIONS: Novel LAPS score may help to facilitate individualized treatment of advanced EGFR-mutated NSCLC receiving EGFR-TKI with or without bevacizumab.PMID:37713583 | DOI:10.1080/07853890.2023.2257227
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Yahua Wu Bin Du Chengliu Lv Xiaohui Ji Jinhuo Lai Source Type: research
The Philadelphia Lung Cancer Learning Community: A Multi-Health-System, Citywide Approach to Lung Cancer Screening
CONCLUSIONS: The sociodemographic characteristics of LCS participants in Philadelphia varied by health system and neighborhood. These results suggest that a multi-center approach to LCS can identify vulnerable areas for future tailored approaches to improving LCS uptake. Future directions should leverage these findings to develop and test collaborative strategies to increase LCS at the community and regional levels.PMID:37713466 | DOI:10.1093/jncics/pkad071
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Julie A Barta Cherie P Erkmen Christine S Shusted Ronald E Myers Chelsea Saia Sarah Cohen Jocelyn Wainwright Charnita Zeigler-Johnson Farouk Dako Richard Wender Gregory C Kane Anil Vachani Katharine A Rendle Source Type: research
Superharmonic and Micro-Ultrasound Imaging with Plane Wave Beamforming Techniques
IEEE Trans Ultrason Ferroelectr Freq Control. 2023 Sep 15;PP. doi: 10.1109/TUFFC.2023.3316120. Online ahead of print.ABSTRACTSuperharmonic contrast imaging (SpHI) suppresses tissue clutter and allows high-contrast visualization of the vasculature. An array-based dual-frequency (DF) probe has been developed for SpHI, integrating a 21 MHz, 256-element micro-ultrasound imaging array with a 2 MHz, 32-element array to take advantage of the broadband nonlinear responses from microbubble contrast agents. In this work, ultrafast imaging with plane waves was implemented for SpHI to increase the acquisition frame rate. Ultrafast ima...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Jing Yang Emmanuel Cherin Jianhua Yin Paul A Dayton F Stuart Foster Christine E M Demore Source Type: research
Equitable implementation of lung cancer screening: avoiding its potential to mirror existing inequities among people who use tobacco
CONCLUSION: The present commentary utilizes information about historical trends in tobacco use to highlight opportunities for targeted outreach efforts to engage communities at high risk with information about the lung cancer screening opportunity. Future efforts toward equitable implementation of lung cancer screening should focus on multi-level implementation strategies that engage and work in concert with community partners to co-create approaches that leverage strengths and reduce barriers within specific communities to achieve the potential of lung cancer screening.PMID:37713024 | DOI:10.1007/s10552-023-01790-z
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Emily Bilenduke Shacoria Anderson Alison Brenner Jessica Currier Jan M Eberth Jaron King Stephanie R Land Betsy C Risendal Jackilen Shannon Leeann N Siegel Mary Wangen Austin R Waters Whitney E Zahnd Jamie L Studts Source Type: research
Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation
Free Radic Biol Med. 2023 Sep 13:S0891-5849(23)00627-5. doi: 10.1016/j.freeradbiomed.2023.09.009. Online ahead of print.ABSTRACTTranscription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) is the principal determinant of the cellular redox homeostasis, contributing to mitochondrial function, integrity and bioenergetics. The main negative regulator of Nrf2 is Kelch-like ECH associated protein 1 (Keap1), a substrate adaptor for Cul3/Rbx1 ubiquitin ligase, which continuously targets Nrf2 for ubiquitination and proteasomal degradation. Loss-of-function mutations in Keap1 occur frequently in lung cancer, leading ...
Source: Free Radical Biology and Medicine - September 15, 2023 Category: Biology Authors: Sharadha Dayalan Naidu Plamena R Angelova Elena V Knatko Chiara Leonardi Miroslav Novak Laureano de la Vega Ian G Ganley Andrey Y Abramov Albena T Dinkova-Kostova Source Type: research
ARHGAP21 inhibits epithelial-mesenchymal transition by inactivating the WNT signaling pathway in non-small cell lung cancer
CONCLUSION: ARHGAP21 downregulation can significantly promote the migration and metastatic ability of NSCLC possibly as a result of WNT signaling pathway activation, which reduces the ubiquitination of β-catenin by affecting the expressions of APC, GSK3β, and Axin.PMID:37712268 | DOI:10.12122/j.issn.1673-4254.2023.08.08
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Z Xie L Liu J Fang X Zhong J Lin F Chen Source Type: research
