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Condition: Kidney Transplantation
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Total 40015 results found since Jan 2013.
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative Glomerulonephritis
CONCLUSIONS: In our cohort, 17% of C3 glomerulopathy/Ig-MPGN cases were associated with rare variants in the CFH, CFI, or C3 genes. In the majority of cases, a quantitative deficiency in factor H or factor I is identified. The presence of a rare variant was associated with poor kidney survival.PMID:37615951 | DOI:10.2215/CJN.0000000000000252
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 24, 2023 Category: Urology & Nephrology Authors: Marie Sophie Meuleman Paula Vieira Martins Carine El Sissy Vincent Audard V éronique Baudouin Dominique Bertrand Frank Bridoux F érielle Louillet Claire Dossier Vincent Esnault No émie Jourde-Chiche Alexandre Karras Marie-Pascale Morin Fran çois Provo Source Type: research
Safety analysis of co-administering tacrolimus and omeprazole in renal transplant recipients - A review
Biomed Pharmacother. 2023 Aug 22;166:115149. doi: 10.1016/j.biopha.2023.115149. Online ahead of print.ABSTRACTTacrolimus is a calcineurin inhibitor used to prevent rejection in allogenic solid organ transplant recipients, which is metabolized in the liver with cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). In turn, proton pump inhibitors (PPIs), such as Omeprazole - a substrate and inhibitor of CYP2C19 and CYP3A4 enzymes - are administered to kidney transplant patients in order to prevent duodenal and gastric ulcer disease, associated with the glucocorticoid treatment. Simultaneous administration of both drugs in r...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 24, 2023 Category: Drugs & Pharmacology Authors: Mi łosz Miedziaszczyk Ilona Idasiak-Piechocka Source Type: research
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative Glomerulonephritis
CONCLUSIONS: In our cohort, 17% of C3 glomerulopathy/Ig-MPGN cases were associated with rare variants in the CFH, CFI, or C3 genes. In the majority of cases, a quantitative deficiency in factor H or factor I is identified. The presence of a rare variant was associated with poor kidney survival.PMID:37615951 | DOI:10.2215/CJN.0000000000000252
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 24, 2023 Category: Urology & Nephrology Authors: Marie Sophie Meuleman Paula Vieira Martins Carine El Sissy Vincent Audard V éronique Baudouin Dominique Bertrand Frank Bridoux F érielle Louillet Claire Dossier Vincent Esnault No émie Jourde-Chiche Alexandre Karras Marie-Pascale Morin Fran çois Provo Source Type: research
Safety analysis of co-administering tacrolimus and omeprazole in renal transplant recipients - A review
Biomed Pharmacother. 2023 Aug 22;166:115149. doi: 10.1016/j.biopha.2023.115149. Online ahead of print.ABSTRACTTacrolimus is a calcineurin inhibitor used to prevent rejection in allogenic solid organ transplant recipients, which is metabolized in the liver with cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). In turn, proton pump inhibitors (PPIs), such as Omeprazole - a substrate and inhibitor of CYP2C19 and CYP3A4 enzymes - are administered to kidney transplant patients in order to prevent duodenal and gastric ulcer disease, associated with the glucocorticoid treatment. Simultaneous administration of both drugs in r...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 24, 2023 Category: Drugs & Pharmacology Authors: Mi łosz Miedziaszczyk Ilona Idasiak-Piechocka Source Type: research
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative Glomerulonephritis
CONCLUSIONS: In our cohort, 17% of C3 glomerulopathy/Ig-MPGN cases were associated with rare variants in the CFH, CFI, or C3 genes. In the majority of cases, a quantitative deficiency in factor H or factor I is identified. The presence of a rare variant was associated with poor kidney survival.PMID:37615951 | DOI:10.2215/CJN.0000000000000252
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 24, 2023 Category: Urology & Nephrology Authors: Marie Sophie Meuleman Paula Vieira Martins Carine El Sissy Vincent Audard V éronique Baudouin Dominique Bertrand Frank Bridoux F érielle Louillet Claire Dossier Vincent Esnault No émie Jourde-Chiche Alexandre Karras Marie-Pascale Morin Fran çois Provo Source Type: research
hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages
CONCLUSION: hUC-MSC transplantation could inhibit the proliferation and differentiation of peripheral blood B cells in the early-stage of MRL/lpr mice, thereby alleviating the plasma inflammatory environment in mice, leading to kidney injury remission. The study provides a new and feasible strategy for SLE treatment.PMID:37605271 | DOI:10.1186/s13287-023-03432-2
Source: Cell Research - August 22, 2023 Category: Cytology Authors: Fengbiao Guo Quanren Pan Ting Chen Shuzhen Liao Shangmei Li Aifen Li Shuxian Chen Jiaxuan Chen Zengzhi Xiao Hongyong Su Lawei Yang Chen Yang Hua-Feng Liu Qingjun Pan Source Type: research
Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial
CONCLUSIONS: Multiple cardiorenal stress biomarkers are strongly prognostic in people with type 2 diabetes and albuminuria. Canagliflozin modestly reduced the longitudinal trajectory of rise in each biomarker. Change in the biomarker level in addition to the baseline level augments the primary outcome prediction.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT02065791.PMID:37603600 | DOI:10.1161/CIRCULATIONAHA.123.065251
Source: Circulation - August 21, 2023 Category: Cardiology Authors: James L Januzzi Reza Mohebi Yuxi Liu Naveed Sattar Hiddo J L Heerspink Eshetu Tefera Muthiah Vaduganathan Javed Butler Yshai Yavin Jingwei Li Carol A Pollock Vlado Perkovic Bruce Neal Michael K Hansen Source Type: research
Pharmaceutical care model in precision medicine in China
Farm Hosp. 2023 Aug 17:S1130-6343(23)00095-8. doi: 10.1016/j.farma.2023.07.004. Online ahead of print.ABSTRACTPharmacy service is to provide individualized pharmaceutical care for patients, which should follow the current evidence-based pharmacy, and constantly verify the evidence and then produce new evidence. In pharmaceutical care, differences are often found in the efficacy and adverse reactions of drugs among individuals, even within individuals, which are closely related to patients' genetics, liver and kidney functions, disease states, and drug interactions. Back in the 1980s, therapeutic drug monitoring (TDM) has b...
Source: Farmacia Hospitalaria - August 19, 2023 Category: Drugs & Pharmacology Authors: Ping Zheng Liqian Mo Boxin Zhao Liren Li Baihong Cen Zhongyuan Xu Yilei Li Source Type: research
Creatine and Creatinine Quantified using Nuclear Magnetic Resonance: A Method Validation Study and Clinical Associations Between Circulating Creatine and Fatigue in Kidney Transplant Recipients
CONCLUSION: An NMR method for measurement of circulating creatine and creatinine which offers the potential for accurate and efficient quantification was developed. The found associations indicate that improving creatine status may play a beneficial role in mitigating fatigue.PMID:37591418 | DOI:10.1016/j.cca.2023.117517
Source: International Journal of Clinical Chemistry - August 17, 2023 Category: Chemistry Authors: Adrian Post Erwin Garcia Irina Shalaurova Steven P Matyus Jessica M Gonz ález-Delgado Caecilia S E Doorenbos Yvonne van der Veen Svati H Shah William E Kraus Daan Kremer Tim J Knobbe Stephan J L Bakker Robin P F Dullaart Margery A Connelly Source Type: research
Pediatric kidney transplantation: outcomes with under and over 6-year-old donors
CONCLUSIONS: Small donors can be considered for pDDKTs, as long as there is an expert team to perform the transplantation.PMID:37591483 | DOI:10.1016/j.jped.2023.07.005
Source: Jornal de Pediatria - August 17, 2023 Category: Pediatrics Authors: Simone Lysakowski Clotilde Druck Garcia Roberta Weisheimer Rohde Santo Pascual Vitola Fabian Silva Pires Vandrea Carla de Souza Pedro Enrico Ventura Roger Kist Source Type: research
