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Condition: Diabetes
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Total 119356 results found since Jan 2013.
Profile of plasma free amino acids, carnitine and acylcarnitines, and JAK2 < sup > v617f < /sup > mutation as potential metabolic markers in children with type 1 diabetic nephropathy
Biomed Chromatogr. 2023 Sep 20:e5747. doi: 10.1002/bmc.5747. Online ahead of print.ABSTRACTFifty diabetic nephropathy (DN) children with type 1 diabetes mellitus (T1DM) and 50 healthy matched controls were included. Chromatographic assays of 14 amino acids, free carnitine and 27 carnitine esters using high-performance liquid chromatography/electrospray ionization-mass spectroscopy, and genetic testing for JAK2v617f mutation using real-time PCR were performed. Patients had significantly lower levels of tyrosine, branched-chain amino acids (BCAAs), and BCAA/AAA (aromatic chain amino acids) ratios, glycine, arginine, ornithin...
Source: Biomedical Chromatography : BMC - September 20, 2023 Category: Biomedical Science Authors: Mohammed H Hassan Omyma Galal Hala M Sakhr Eman B Kamaleldeen Nadia Farouk Zekry Ekram Fateen Rana Toghan Source Type: research
Premature pubarche during minipuberty - literature review and two case reports
CONCLUSIONS: Isolated pubic hair in infancy as a mild, self-limiting variant of precocious puberty in infants should be a diagnosis of exclusion. The condition resolves spontaneously, but it absolutely requires further follow-up to exclude serious aetiology in the case of puberty progression.PMID:37728463 | PMC:PMC10411085 | DOI:10.5114/pedm.2023.129343
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Anna Raku ś-Kwiatosz El żbieta Budzyńska Iwona Be ń-Skowronek Source Type: research
Association of serum phthalates exposure with incident type 2 diabetes risk in Chinese population: A nested case-control study
Ecotoxicol Environ Saf. 2023 Sep 18;265:115493. doi: 10.1016/j.ecoenv.2023.115493. Online ahead of print.ABSTRACTProspective epidemiological evidence was lacking on the association of phthalates (PAEs) exposure with incident type 2 diabetes mellitus (T2DM) risk. In present nested case-control study, we identified 1006 T2DM cases and matched 1006 controls based on Dongfeng-Tongji cohort study, and 6 PAEs were detected in baseline serum. The conditional logistic regression model, Bayesian kernel machine regression (BKMR) model and Quantile-based g-computation were applied to evaluate the associations of determined PAEs, eith...
Source: Ecotoxicology and Environmental Safety - September 20, 2023 Category: Environmental Health Authors: Shiyang Zhang Xu Cheng Chengyong Jia Jun An Xin Zhang Peiwen Li Youbing Guan Yan Yan Zhuoya Zhao Yuenan Liu Tao Jing Meian He Source Type: research
"The obesity pandemic" in the COVID-19 pandemic - new treatment for an old problem
This article provides a review of the literature on the recent worsening of obesity in the paediatric population, with particular emphasis on the importance of the COVID-19 pandemic. New methods of fighting obesity with the use of telemedicine and current methods of pharmacotherapy, including new drugs, are presented.PMID:37728462 | PMC:PMC10411083 | DOI:10.5114/pedm.2023.129342
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kalina Fabin-Czepiel Karolina Pieczy ńska-Chapuła Gra żyna Deja Source Type: research
Subclinical hypothyroidism in children and adolescents as mild dysfunction of the thyroid gland: a single-center study
Pediatr Endocrinol Diabetes Metab. 2023;29(2):97-103. doi: 10.5114/pedm.2023.124266.ABSTRACTINTRODUCTION: Subclinical hypothyroidism (SH) is a biochemical diagnosis made when a serum thyroid-stimulating hormone (TSH) is ele-vated with circulating thyroid hormone levels within their reference ranges.AIM OF THE STUDY: Aim of our prospective non-randomized study was to evaluate the course of SH.MATERIAL AND METHODS: All patients with suspicion of SH referred to the Endocrinology Outpatient Clinic between 2014 and 2018 were recruited to prospective study.RESULTS: A total of 130 patients with SH were recruited for this study. T...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kamila Szeliga Aleksandra Antosz Karolina Skrzynska Barbara Kalina-Faska Aneta Gawlik Source Type: research
Lipid metabolism and renal function markers in obese adolescents
CONCLUSIONS: Renal function of the obese adolescents included in the study was normal and the associations with lipid metabolism were poorly expressed.PMID:37728460 | PMC:PMC10411080 | DOI:10.5114/pedm.2023.125612
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Aleksandra Radosz Anna Obuchowicz Source Type: research
The positive impact of lifestyle intervention on selected mio- and chemokines levels in prepubertal children with obesity
CONCLUSIONS: Personalized diet modification and regular, daily exercises may positively influence on the levels of irisin and chemerin.PMID:37728459 | PMC:PMC10411087 | DOI:10.5114/pedm.2023.127273
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Agnieszka Kozio ł-Kozakowska Ma łgorzata Wójcik Dominika Janu ś Jerzy Starzyk Source Type: research
Are menstrual disorders in adolescent girls related to metabolic disorders?
CONCLUSIONS: Adolescent girls with menstrual disorders are insulin resistant, regardless of PCOS diagnosis. The severity of menstrual disorders may be related to the incidence of lipid disorders in adolescent girls.PMID:37728458 | PMC:PMC10411084 | DOI:10.5114/pedm.2023.125364
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: El żbieta Foryś Adrianna Baran Aleksandra Dziurdzia Ewelina Jarosz-W ójcik Pawe ł Matusik Aneta Gawlik Ryszard Tomaszewski Agnieszka Zachurzok Source Type: research
Assessment of fibroblast growth factor 21 in children with type 1 diabetes mellitus in relation to microvascular complications
CONCLUSIONS: FGF21 is significantly higher among children with DM1 than in controls. However, its role in diabetic microvascular complica-tions needs further assessment.PMID:37728457 | PMC:PMC10411091 | DOI:10.5114/pedm.2022.121372
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Nermien Tantawy Eman Sherif Randa M Matter Nouran Salah Nour Eldin Abozeid Heba Atif Source Type: research
Potential bacteriophages to overcome bacterial infection of Alcaligenes faecalis in diabetic ulcer
CONCLUSIONS: The 6 isolates that were isolated had the ability to infect by forming a prophage that could inhibit the growth of Alcaligenes faecalis and other pathogenic bacteria in diabetic ulcers.PMID:37728456 | PMC:PMC10411081 | DOI:10.5114/pedm.2023.125363
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Erlia Narulita Vivi Indah Nur Cahyati Riska A Febrianti Mochammad Iqbal Source Type: research
Construction and functional evaluation of oral long-acting insulin hydrogel microparticles based on physical and chemical double crosslinking
The objective of this study was to enhance the convenience and effectiveness of diabetes treatment by developing hydrogel microparticles as an oral insulin delivery system, aiming to reduce the necessity for frequent treatments. The hydrogel microparticles were prepared with polysaccharides through a combination of physical and chemical crosslinking method, they achieved good results in insulin loading efficiency (70 %), insulin release efficiency (98 %) and sustained release time (>20 h). The effective transmembrane transport was validated using an intestinal epithelial cell model, which demonstrated a continuous hypog...
Source: International Journal of Biological Macromolecules - September 20, 2023 Category: Biochemistry Authors: ShengQin Chen QingYa Miao Yang Liu Qiao Xiao YuKai Lin Yu Yang FengBiao Guo Source Type: research
Physician Preferences when Selecting Candidates for Lower-Quality Kidney Offers
CONCLUSIONS: Physicians appear to consider the recipient characteristics that inform expected post-transplant survival score when deciding whether to accept a marginal kidney for a given recipient.PMID:37729938 | DOI:10.2215/CJN.0000000000000302
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 20, 2023 Category: Urology & Nephrology Authors: Juan M Gonzalez Sepulveda Sanjay Mehrotra Jui-Chen Yang Karolina J Schantz Yolanda Becker Richard Formica Daniela P Ladner Dixon Kaufman John Friedewald Source Type: research
Hyperpolarized 1- < sup > 13 < /sup > Cpyruvate Magnetic Resonance Spectroscopy Shows That Agmatine Increased Lactate Production in the Brain of Type 2 Diabetic Mice
CONCLUSION: Agmatine influences the NADH/NAD+ redox state in the brains of T2DM mice, which may be connected with enhanced cognitive performance and increased conversion of HP [1-13C]pyruvate to HP [1-13C]lactate.PMID:37727922 | DOI:10.3349/ymj.2022.0554
Source: Yonsei Medical Journal - September 20, 2023 Category: Universities & Medical Training Authors: Young-Suk Choi Jae Eun Song Eosu Kim Chul Hoon Kim Jong Eun Lee Ho-Taek Song Source Type: research
Health of people with selected citizenships in Germany: prevalence of non-communicable diseases and associated social as well as migration-related factors
DISCUSSION: Given the importance of subjective sense of belonging to the society in Germany and self-reported experience of discrimination for the health outcomes studied, the results point to health inequalities among people with selected citizenships that may indicate mechanisms of social exclusion.PMID:37728772 | DOI:10.1007/s00103-023-03767-4
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - September 20, 2023 Category: International Medicine & Public Health Authors: Susanne Bartig Marleen Bug Carmen Koschollek Katja Kajikhina Miriam Blume Manuel Siegert Christin Heidemann Lena Walther Hannelore Neuhauser Claudia H övener Source Type: research
Measuring continuity of care for diabetes: which visits to include?
CONCLUSIONS: Continuity values differed substantially depending on which provider specialties were included. The importance of this variation is uncertain, as continuity was weakly associated with ED visits using each of the measures.PMID:37729533 | DOI:10.37765/ajmc.2023.89431
Source: The American Journal of Managed Care - September 20, 2023 Category: Health Management Authors: Kevin R Riggs Caroline A Presley April A Agne Carrie R Howell Lei Huang Michael J Mugavero Emily B Levitan Andrea L Cherrington Source Type: research
