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Drug: Estradiol
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Total 6523 results found since Jan 2013.
Electroacupuncture stimulating Zhongji (CV3), Guanyuan (CV4), and bilateral Dahe (KI12) attenuates inflammation in rats with chronic nonbacterial prostatitis induced by estradiol through inhibiting toll-like receptor 4 pathway
CONCLUSIONS: Our findings suggested that EA could relieve pelvic pain and attenuate prostatic inflammation in estradiol-induced CNP rats. The underlying mechanism may be related to the inhibition of the TLR4/NF-κB signaling pathway.PMID:37679984 | PMC:PMC10465839 | DOI:10.19852/j.cnki.jtcm.20230608.001
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: L I Zhihao Han Wenjun Song Xiuling L I Yan Chen Yuelai Source Type: research
Competitive ECL immunosensor for ultrasensitive 17 β-estradiol detection based on synergistic promotion strategy using CdSe-ZnSe nanocomposites
Talanta. 2023 Sep 5;267:125160. doi: 10.1016/j.talanta.2023.125160. Online ahead of print.ABSTRACTA novel competitive ECL immunosensor for detection of 17β-Estradiol (E2) has been fabricated successfully. CdSe-ZnSe nanocomposites (CdSe-ZnSe NCs) with high catalytic properties, large surface area and good conductivity were used synergistically as the ECL nanocarriers of Pt nanoparticles (PtNPs). The ECL intensity of CdSe-ZnSe NCs increased and stabilized with luminol-PtNPs (luminol-PtNPs@CdSe-ZnSe NCs) because of electron transfer. To achieve the successful assembling of competitive ultrasensitive ECL immunosensor with hig...
Source: Talanta - September 7, 2023 Category: Chemistry Authors: Romana Manzoor Aniqa Sehrish Huan Wang Ren Xiang Yuyang Li Dan Wu Qin Wei Source Type: research
Cystatin C-Based eGFR Changes during Gender-Affirming Hormone Therapy in Transgender Individuals
CONCLUSIONS: In this cohort of transgender individuals, cystatin C-based eGFR increased with estradiol and anti-androgen therapy and decreased with testosterone therapy.PMID:37678248 | DOI:10.2215/CJN.0000000000000289
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 7, 2023 Category: Urology & Nephrology Authors: Sarah A van Eeghen Chantal M Wiepjes Guy T'Sjoen Natalie J Nokoff Martin den Heijer Petter Bjornstad Dani ël H van Raalte Source Type: research
Effects of sex hormones on vascular reactivity in boys with hypospadias
CONCLUSION: In healthy boys, testosterone and 17β-estradiol promote a vasoconstrictor phenotype whereas in boys with hypospadias, these sex hormones reduce vasoconstriction, with androgens promoting vasorelaxation. Differences in baseline artery function may therefore be sex hormone independent and the impact of early-life variations in androgen exposure on vascular function needs further study.PMID:37672642 | DOI:10.1210/clinem/dgad525
Source: The Journal of Clinical Endocrinology and Metabolism - September 6, 2023 Category: Endocrinology Authors: Angela K Lucas-Herald Augusto C Montezano Rheure Alves-Lopes Laura Haddow Stuart O'Toole Martyn Flett Boma Lee S Basith Amjad Mairi Steven Jane McNeilly Katriona Brooksbank Rhian M Touyz S Faisal Ahmed Source Type: research
Overexpression of Pde4d in rat granulosa cells inhibits maturation and atresia of antral follicles to induce polycystic ovary
CONCLUSION: Upregulation of Pde4d may contribute to polycystic ovary syndrome by impeding follicle maturation and preventing apoptotic atresia.PMID:37673361 | DOI:10.1016/j.bbadis.2023.166869
Source: Biochimica et Biophysica Acta - September 6, 2023 Category: Biochemistry Authors: Lu-Yang Jin Jia-En Yu Hai-Yan Xu Bin Chen Qian Yang Ye Liu Meng-Xi Guo Cheng-Liang Zhou Yi Cheng Hai-Yan Pang Hai-Yan Wu Jian-Zhong Sheng He-Feng Huang Source Type: research
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain
Biol Pharm Bull. 2023;46(9):1194-1202. doi: 10.1248/bpb.b23-00140.ABSTRACTEthanol is the most commonly used toxic chemical in human cultures. Ethanol predominantly damages the brain causing various neurological disorders. Astrocytes are important cellular targets of ethanol in the brain and are involved in alcoholic symptoms. Recent studies have revealed the diversity of astrocyte populations in the brain. However, it is unclear how the different astrocyte populations respond to an excess of ethanol. Here we examined the effect of binge ethanol levels on astrocytes in the mouse brainstem and cerebellum. Ethanol administrat...
Source: Biological and Pharmaceutical Bulletin - September 4, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Hasegawa Mari Kondo Source Type: research
Spexin role in human granulosa cells physiology and PCOS: expression and negative impact on steroidogenesis and proliferation
Biol Reprod. 2023 Sep 2:ioad108. doi: 10.1093/biolre/ioad108. Online ahead of print.ABSTRACTSpexin (SPX) is a novel neuropeptide and adipokine negatively correlated with obesity and insulin resistance. A recent study investigated expression and regulatory function of SPX in the hypothalamus and pituitary; however, the effect on ovarian function is still unknown. The aim of this study was to characterize the expression of SPX and its receptors, galanin receptors 2 and 3 (GALR2/3) in the human ovary and to study its in vitro effect on granulosa cells (GC) function. Follicular fluid (FF) and GC were obtained from normal weigh...
Source: Reproductive Biology - September 2, 2023 Category: Reproduction Medicine Authors: Patrycja Kurowska Monika Dawid Julia Oprocha Natalia Repekta Lo ïse Serra Anthony Estienne Piotr Pawlicki Ma łgorzata Kotula-Balak Fabrice Gu érif Joelle Dupont Agnieszka Rak Source Type: research
Potential risk of estrogenic compounds produced by water blooms to aquatic environment
In conclusion, our study documents undetectable or relatively low estrogenic potential of biomass extracts from both environmental freshwater blooms and studied laboratory cultured cyanobacterial and algae species. Nevertheless, in case of very high-density water blooms, even this low estrogenicity (detected for two cyanobacterial species) could lead to EEQ content in biomass reaching effect-based trigger values indicating potential risk, if recalculated per water volume at field sites. However, these levels would not occur in water under realistic environmental scenarios and the potential estrogenic effects would be most ...
Source: Chemosphere - September 1, 2023 Category: Chemistry Authors: Marie Smutn á Jakub Jav ůrek Lud ěk Sehnal Zuzana Tou šová Barbora Jav ůrková Eli ška Sychrová Olga Lep šová-Skácelová Kl ára Hilscherová Source Type: research
Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence
CONCLUSION: This is the first study to show the antidepressant effect of LBP. Although additional research is needed, LBP may be considered a potential new antidepressant.PMID:37654035
Source: Croatian Medical Journal - September 1, 2023 Category: General Medicine Authors: Hayriye Soyt ürk Bihter G ökçe Bozat Fatma Pehlivan Karakas Hamit Coskun Tulin Firat Source Type: research
