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Drug: Nicotine

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Analysis of nicotine in plasma, brain, and hair samples with the same liquid chromatography-tandem mass spectrometry method
Rapid Commun Mass Spectrom. 2023 Sep 15;37(17):e9613. doi: 10.1002/rcm.9613.NO ABSTRACTPMID:37580504 | DOI:10.1002/rcm.9613
Source: Rapid Communications in Mass Spectrometry : RCM - August 14, 2023 Category: Chemistry Authors: Steven W Blue Cindy T McEvoy Eliot R Spindel Lyndsey E Shorey-Kendrick Michael H Davies Shannon M O'Sullivan David W Erikson Source Type: research

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Assessment of urinary aromatic amines in Brazilian pregnant women and association with DNA damage: Influence of genetic diversity, lifestyle, and environmental and socioeconomic factors
Environ Pollut. 2023 Aug 10;335:122366. doi: 10.1016/j.envpol.2023.122366. Online ahead of print.ABSTRACTAromatic amines (AAs) are polar organic chemicals with a wide environmental distribution originating from various sources, such as tobacco smoke, diesel exhaust, and dermal absorption from textile products with azo dyes. The toxicity profile of AAs is directly related to the amino group's metabolic activation and the generation of the reactive intermediate, forming DNA adducts and potential carcinogenicity. Urinary levels of 8-hydroxy-2'-deoxyguanosine (8OHdG) are an important biomarker of DNA damage. Since AAs have bee...
Source: Environmental Pollution - August 12, 2023 Category: Environmental Health Authors: Mar ília Cristina Oliveira Souza Neus Gonz ález Joaquim Rovira Marta Herrero Montse Marqu ès Mart í Nadal Fernando Barbosa Jos é Luis Domingo Source Type: research

Clinical Practice Guideline of Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on Pharmacological Treatment of Tobacco Dependence 2023
CONCLUSIONS: The answers to the 12 questions allow us to extract recommendations and algorithms for the pharmacological treatment of tobacco dependence.PMID:37567792 | DOI:10.1016/j.arbres.2023.07.024
Source: Archivos de Bronconeumologia - August 11, 2023 Category: Respiratory Medicine Authors: Carlos R ábade-Castedo Jos é Ignacio de Granda-Orive Juan Antonio Riesco-Miranda Eva De Higes-Mart ínez Ángela Ramos-Pinedo Eva Cabrera-C ésar Jaime Signes-Costa Mi ñana Marcos Garc ía Rueda Esther Pastor-Espl á Carlos A Jim énez-Ruiz Source Type: research

Protection of Children and Adolescents from Tobacco and Nicotine
Pediatr Ann. 2023 Aug;52(8):e277-e278. doi: 10.3928/19382359-20230711-01. Epub 2023 Aug 1.NO ABSTRACTPMID:37561823 | DOI:10.3928/19382359-20230711-01
Source: Pediatric Annals - August 10, 2023 Category: Pediatrics Authors: Joseph R Hageman Lolita Alcocer Alkureishi Gregg J Montalto Source Type: research