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Relevance of medical information obtained from ChatGPT: Are large language models friends or foes?
Arch Cardiovasc Dis. 2023 Sep 9:S1875-2136(23)00164-X. doi: 10.1016/j.acvd.2023.07.009. Online ahead of print.NO ABSTRACTPMID:37718185 | DOI:10.1016/j.acvd.2023.07.009
Source: Archives of Cardiovascular Diseases - September 17, 2023 Category: Cardiology Authors: Jules Mesnier Gaspard Suc Neila Sayah J érémie Abtan Philippe Gabriel Steg Source Type: research

Contribution of the 6-minutes walking test and the plasma NT-proBNP at admission and discharge to the prognostic evaluation of patients with NYHA class II-III Heart Failure.
CONCLUSION: 6MWT and NT-proBNP variations from admission to discharge have been necessary to evaluate the prognosis of patients with CHF.PMID:37717311 | DOI:10.1016/j.ancard.2023.101639
Source: Annales de Cardiologie et d'Angeiologie - September 17, 2023 Category: Cardiology Authors: G R C Millogo A Thiam Tall T A A Seghda Y Kambir é E Nongkouni Y E Dabir é L J Kagamb éga J K Kologo V N Yam éogo X Marcaggi P Zabsonr é Source Type: research

Relevance of medical information obtained from ChatGPT: Are large language models friends or foes?
Arch Cardiovasc Dis. 2023 Sep 9:S1875-2136(23)00164-X. doi: 10.1016/j.acvd.2023.07.009. Online ahead of print.NO ABSTRACTPMID:37718185 | DOI:10.1016/j.acvd.2023.07.009
Source: Archives of Cardiovascular Diseases - September 17, 2023 Category: Cardiology Authors: Jules Mesnier Gaspard Suc Neila Sayah J érémie Abtan Philippe Gabriel Steg Source Type: research

Contribution of the 6-minutes walking test and the plasma NT-proBNP at admission and discharge to the prognostic evaluation of patients with NYHA class II-III Heart Failure.
CONCLUSION: 6MWT and NT-proBNP variations from admission to discharge have been necessary to evaluate the prognosis of patients with CHF.PMID:37717311 | DOI:10.1016/j.ancard.2023.101639
Source: Annales de Cardiologie et d'Angeiologie - September 17, 2023 Category: Cardiology Authors: G R C Millogo A Thiam Tall T A A Seghda Y Kambir é E Nongkouni Y E Dabir é L J Kagamb éga J K Kologo V N Yam éogo X Marcaggi P Zabsonr é Source Type: research

Relevance of medical information obtained from ChatGPT: Are large language models friends or foes?
Arch Cardiovasc Dis. 2023 Sep 9:S1875-2136(23)00164-X. doi: 10.1016/j.acvd.2023.07.009. Online ahead of print.NO ABSTRACTPMID:37718185 | DOI:10.1016/j.acvd.2023.07.009
Source: Archives of Cardiovascular Diseases - September 17, 2023 Category: Cardiology Authors: Jules Mesnier Gaspard Suc Neila Sayah J érémie Abtan Philippe Gabriel Steg Source Type: research

An Update on Inflammation in Atherosclerosis: How to Effectively Treat Residual Risk
This study reviewed the contribution of inflammation to atherosclerotic cardiovascular disease (ASCVD), which has gained widespread recognition in recent years.METHODS: This critical review evaluated how recent publications and ongoing clinical trials in atherosclerotic inflammation will affect clinical care.FINDINGS: Key trials, including CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) with canakinumab (interleukin-1β inhibition), and COLCOT (Colchicine Cardiovascular Outcomes Trial) and LoDoCo2 (Low Dose Colchicine 2) with colchicine, have shown that suppressing inflammation can improve outcomes in ASCV...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: N Mohammadnia T S J Opstal S El Messaoudi W A Bax J H Cornel Source Type: research

Unveiling the hidden landscape of arterial diseases at single cell resolution
Can J Cardiol. 2023 Sep 14:S0828-282X(23)01663-X. doi: 10.1016/j.cjca.2023.09.009. Online ahead of print.ABSTRACTHigh-resolution single cell technologies have shed light on the pathogenesis of cardiovascular diseases by enabling the discovery of novel cellular and transcriptomic signatures associated with various conditions, and uncovering new contributions of inflammatory processes, immunity, metabolic stress, and risk factors. We review the information obtained from studies using single cell technologies in tissues with atherosclerosis and aortic aneurysms. Insights are provided on the biology of endothelial, smooth musc...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Corey A Scipione Sharon J Hyduk Chanele K Polenz Myron I Cybulsky Source Type: research

Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research

Cholesterol homeostasis, mechanisms of molecular pathways, and cardiac health: a current outlook
Curr Probl Cardiol. 2023 Sep 14:102081. doi: 10.1016/j.cpcardiol.2023.102081. Online ahead of print.ABSTRACTThe metabolism of lipoproteins, which regulates the transit of the lipid to and from tissues, is crucial to maintaining cholesterol homeostasis. Cardiac remodeling is referred to as a set of molecular, cellular, and interstitial changes that, following injury, affect the size, shape, function, mass, and geometry of the heart. Acetyl coenzyme A (acetyl CoA), which can be made from glucose, amino acids, or fatty acids, is the precursor for the synthesis of cholesterol. In this article, authors explain concepts behind c...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Rajiv Kumar Neelam Chhillar Dhruv Sanjay Gupta Ginpreet Kaur Shailey Singhal Tanya Chauhan Source Type: research

Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE < sup > -/- < /sup > mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
CONCLUSION: Our findings suggest that ZCHP can effectively attenuate AS progression by inhibiting MAPK/ERK signaling-mediated apoptosis via FGFR3 hypermethylation in the promoter region.PMID:37716492 | DOI:10.1016/j.jep.2023.117188
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Yan Zhang Dandan Li Zijun Jia Jun Mei Ya Wang Ying Zhang Qingbing Zhou Fengqin Xu Source Type: research

Home-based exercise improves subclinical atherosclerosis marker in multiple sclerosis
CONCLUSION: The EX group had modest, yet significant, increases in aerobic capacity over the 12-week period, coupled with improvements in T25FW speed and vasodilatory reactivity. A home-based exercise intervention can improve outcomes of a subclinical marker of atherosclerosis, which provides a basis for examining these outcomes in persons prescreened for CVD-related comorbidities and/or mobility issues.PMID:37716212 | DOI:10.1016/j.msard.2023.105002
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Tracy Baynard Garett J Griffith Sang Ouk Wee Neil J McMillan Rachel E Bollaert Robert W Motl Bo Fernhall Source Type: research

MiRNA a New Insight in Metabolic and Human Diseases: A Review
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):102-110. doi: 10.14715/cmb/2023.69.8.16.ABSTRACTThe purpose of this research is to examine existing studies on the association between microRNAs (miRNA) and age-related disorders. The miRNAs are small, noncoding RNA molecules with the ability to regulate gene expression. These are well-established in extracellular circulation, including various types of diseases such as cancer, cardiovascular diseases, and diabetes. Similarly, several miRNAs are associated with certain age-related conditions, such as increased miR-21 expression in cancer patients. Besides that, the miR-122 ...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Ibrahim Jafri Source Type: research

An Update on Inflammation in Atherosclerosis: How to Effectively Treat Residual Risk
This study reviewed the contribution of inflammation to atherosclerotic cardiovascular disease (ASCVD), which has gained widespread recognition in recent years.METHODS: This critical review evaluated how recent publications and ongoing clinical trials in atherosclerotic inflammation will affect clinical care.FINDINGS: Key trials, including CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) with canakinumab (interleukin-1β inhibition), and COLCOT (Colchicine Cardiovascular Outcomes Trial) and LoDoCo2 (Low Dose Colchicine 2) with colchicine, have shown that suppressing inflammation can improve outcomes in ASCV...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: N Mohammadnia T S J Opstal S El Messaoudi W A Bax J H Cornel Source Type: research

Unveiling the hidden landscape of arterial diseases at single cell resolution
Can J Cardiol. 2023 Sep 14:S0828-282X(23)01663-X. doi: 10.1016/j.cjca.2023.09.009. Online ahead of print.ABSTRACTHigh-resolution single cell technologies have shed light on the pathogenesis of cardiovascular diseases by enabling the discovery of novel cellular and transcriptomic signatures associated with various conditions, and uncovering new contributions of inflammatory processes, immunity, metabolic stress, and risk factors. We review the information obtained from studies using single cell technologies in tissues with atherosclerosis and aortic aneurysms. Insights are provided on the biology of endothelial, smooth musc...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Corey A Scipione Sharon J Hyduk Chanele K Polenz Myron I Cybulsky Source Type: research

Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research